AKAP6: A-kinase anchoring protein 6
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S197 TKEGRLDS LTEVDDS 1 26 - - - - - - 26 - - - - - - - - - - - - - T199 EGRLDSLT EVDDSGQ 1 8 - - - - - - - - - - - - 4 4 - - - - - - T368 PVPCENAT PKRTIRD 1 9 - - - - - - 9 - - - - - - - - - - - - - S383 CFNYNEDS PTQPTLP 3 46 - - - - - - 9 - 14 10 - - - - - - - - 13 - T385 NYNEDSPT QPTLPKR 1 9 - - - - - - - - 7 2 - - - - - - - - - - S424 LKPEMSRS TPSLVDP 1 46 - - - - - - 46 - - - - - - - - - - - - - S448 LQSSYPNS PSAASQS 1 8 - - - - - - - - 4 4 - - - - - - - - - - S453 PNSPSAAS QSYECLH 1 10 - - - - - - 10 - - - - - - - - - - - - - S455 SPSAASQS YECLHKV 2 62 - - - - - - 54 - 4 4 - - - - - - - - - - S481 HIKEISSS LGRLNDC 2 42 - - - - - - 36 - - - - - - - - - - - 6 -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S197 TKEGRLDS LTEVDDS - - - - - - - - - - - T199 EGRLDSLT EVDDSGQ - - - - - - - - - - - T368 PVPCENAT PKRTIRD - - - - - - - - - - - S383 CFNYNEDS PTQPTLP - - - - - - - - - - - T385 NYNEDSPT QPTLPKR - - - - - - - - - - - S424 LKPEMSRS TPSLVDP - - - - - - - - - - - S448 LQSSYPNS PSAASQS - - - - - - - - - - - S453 PNSPSAAS QSYECLH - - - - - - - - - - - S455 SPSAASQS YECLHKV - - - - - - - - - - - S481 HIKEISSS LGRLNDC - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S197
T199
T368
S383
T385
S424
S448
S453
S455
S481
S593
S610
S627
S672
S676
S697
T906
S908
T1059
S1066
S1067
S1073
S1325
S1329
S1332
S1335
S1431
S1566
S1567
S1593
S1595
S1644
S1653
S1655
S1717
S1941
T1978
S1999
T2135
S2296
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S197 T199 T368 S383 T385 S424 S448 S453 S455 S481 S593 S610 S627 S672 S676 S697 T906 S908 T1059 S1066 S1067 S1073 S1325 S1329 S1332 S1335 S1431 S1566 S1567 S1593 S1595 S1644 S1653 S1655 S1717 S1941 T1978 S1999 T2135 S2296 protein RNA SCNV methylation CCRCC S197 T199 T368 S383 T385 S424 S448 S453 S455 S481 S593 S610 S627 S672 S676 S697 T906 S908 T1059 S1066 S1067 S1073 S1325 S1329 S1332 S1335 S1431 S1566 S1567 S1593 S1595 S1644 S1653 S1655 S1717 S1941 T1978 S1999 T2135 S2296 protein RNA SCNV methylation COAD S197 T199 T368 S383 T385 S424 S448 S453 S455 S481 S593 S610 S627 S672 S676 S697 T906 S908 T1059 S1066 S1067 S1073 S1325 S1329 S1332 S1335 S1431 S1566 S1567 S1593 S1595 S1644 S1653 S1655 S1717 S1941 T1978 S1999 T2135 S2296 protein RNA SCNV methylation GBM S197 T199 T368 S383 T385 S424 S448 S453 S455 S481 S593 S610 S627 S672 S676 S697 T906 S908 T1059 S1066 S1067 S1073 S1325 S1329 S1332 S1335 S1431 S1566 S1567 S1593 S1595 S1644 S1653 S1655 S1717 S1941 T1978 S1999 T2135 S2296 protein RNA SCNV methylation HNSCC S197 T199 T368 S383 T385 S424 S448 S453 S455 S481 S593 S610 S627 S672 S676 S697 T906 S908 T1059 S1066 S1067 S1073 S1325 S1329 S1332 S1335 S1431 S1566 S1567 S1593 S1595 S1644 S1653 S1655 S1717 S1941 T1978 S1999 T2135 S2296 protein RNA SCNV methylation LSCC S197 T199 T368 S383 T385 S424 S448 S453 S455 S481 S593 S610 S627 S672 S676 S697 T906 S908 T1059 S1066 S1067 S1073 S1325 S1329 S1332 S1335 S1431 S1566 S1567 S1593 S1595 S1644 S1653 S1655 S1717 S1941 T1978 S1999 T2135 S2296 protein RNA SCNV methylation LUAD S197 T199 T368 S383 T385 S424 S448 S453 S455 S481 S593 S610 S627 S672 S676 S697 T906 S908 T1059 S1066 S1067 S1073 S1325 S1329 S1332 S1335 S1431 S1566 S1567 S1593 S1595 S1644 S1653 S1655 S1717 S1941 T1978 S1999 T2135 S2296 protein RNA SCNV methylation OV S197 T199 T368 S383 T385 S424 S448 S453 S455 S481 S593 S610 S627 S672 S676 S697 T906 S908 T1059 S1066 S1067 S1073 S1325 S1329 S1332 S1335 S1431 S1566 S1567 S1593 S1595 S1644 S1653 S1655 S1717 S1941 T1978 S1999 T2135 S2296 protein RNA SCNV methylation PDAC S197 T199 T368 S383 T385 S424 S448 S453 S455 S481 S593 S610 S627 S672 S676 S697 T906 S908 T1059 S1066 S1067 S1073 S1325 S1329 S1332 S1335 S1431 S1566 S1567 S1593 S1595 S1644 S1653 S1655 S1717 S1941 T1978 S1999 T2135 S2296 protein RNA SCNV methylation UCEC S197 T199 T368 S383 T385 S424 S448 S453 S455 S481 S593 S610 S627 S672 S676 S697 T906 S908 T1059 S1066 S1067 S1073 S1325 S1329 S1332 S1335 S1431 S1566 S1567 S1593 S1595 S1644 S1653 S1655 S1717 S1941 T1978 S1999 T2135 S2296 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S197
T199
T368
S383
T385
S424
S448
S453
S455
S481
S593
S610
S627
S672
S676
S697
T906
S908
T1059
S1066
S1067
S1073
S1325
S1329
S1332
S1335
S1431
S1566
S1567
S1593
S1595
S1644
S1653
S1655
S1717
S1941
T1978
S1999
T2135
S2296
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S197
T199
T368
S383
T385
S424
S448
S453
S455
S481
S593
S610
S627
S672
S676
S697
T906
S908
T1059
S1066
S1067
S1073
S1325
S1329
S1332
S1335
S1431
S1566
S1567
S1593
S1595
S1644
S1653
S1655
S1717
S1941
T1978
S1999
T2135
S2296
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.