MED13L: mediator complex subunit 13L
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T326 SNCGMPLT PPTSPEQ 2 18 - - - - - - 9 - 5 4 - - - - - - - - - - T329 GMPLTPPT SPEQAIL 1 6 - - - - - - - - - - - - - - - - 5 1 - - S330 MPLTPPTS PEQAILG 1 6 - - - - - - - - - - - - - - - - 5 1 - - T398 SKRSQMST PTLEEEP 5 137 - - - - 22 14 - - 12 5 - - 5 4 22 3 - - 34 16 T400 RSQMSTPT LEEEPAS 5 71 - - - - 11 7 - - 16 11 4 4 4 5 - - - - - 9 S407 TLEEEPAS NPATWDF 3 72 27 - - - - - - - - - 19 17 5 4 - - - - - - S550 NPMDSPHS PISPLPP 2 47 - - - - - - - - - - 5 5 - - - - - - 30 7 S553 DSPHSPIS PLPPTLS 2 47 - - - - - - - - - - 5 5 - - - - - - 30 7 S560 SPLPPTLS PQPRGQE 1 17 - - - - - - - - - - - - - - - - - - 12 5 S575 TESLDPPS VPVNPAL 8 223 8 - 16 15 9 9 - - 17 10 10 10 9 8 - - 51 21 19 11
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T326 SNCGMPLT PPTSPEQ - - - - - - - - - - - T329 GMPLTPPT SPEQAIL - - - - - - - - - - - S330 MPLTPPTS PEQAILG - - - - - - - - - - - T398 SKRSQMST PTLEEEP -0.051 - - -0.013 - - - - - - -0.78 T400 RSQMSTPT LEEEPAS - - - - - - - - - - - S407 TLEEEPAS NPATWDF - - - - - - - - - - - S550 NPMDSPHS PISPLPP - - - - - - - - - - - S553 DSPHSPIS PLPPTLS - - - - - - - - - - - S560 SPLPPTLS PQPRGQE - - - - - - - - - - - S575 TESLDPPS VPVNPAL -0.74 - - - - - - - - -0.74 -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T326
T329
S330
T398
T400
S407
S550
S553
S560
S575
Y583
S747
T758
S762
T763
S817
S826
S870
S878
S923
S1003
T1043
T1050
T1053
T1065
S1067
S1071
S1081
S2083
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T326 T329 S330 T398 T400 S407 S550 S553 S560 S575 Y583 S747 T758 S762 T763 S817 S826 S870 S878 S923 T1043 T1050 T1053 T1065 S1067 S1071 S1081 S2083 protein RNA SCNV methylation CCRCC T326 T329 S330 T398 T400 S407 S550 S553 S560 S575 Y583 S747 T758 S762 T763 S817 S826 S870 S878 S923 T1043 T1050 T1053 T1065 S1067 S1071 S1081 S2083 protein RNA SCNV methylation COAD T326 T329 S330 T398 T400 S407 S550 S553 S560 S575 Y583 S747 T758 S762 T763 S817 S826 S870 S878 S923 T1043 T1050 T1053 T1065 S1067 S1071 S1081 S2083 protein RNA SCNV methylation GBM T326 T329 S330 T398 T400 S407 S550 S553 S560 S575 Y583 S747 T758 S762 T763 S817 S826 S870 S878 S923 T1043 T1050 T1053 T1065 S1067 S1071 S1081 S2083 protein RNA SCNV methylation HNSCC T326 T329 S330 T398 T400 S407 S550 S553 S560 S575 Y583 S747 T758 S762 T763 S817 S826 S870 S878 S923 T1043 T1050 T1053 T1065 S1067 S1071 S1081 S2083 protein RNA SCNV methylation LSCC T326 T329 S330 T398 T400 S407 S550 S553 S560 S575 Y583 S747 T758 S762 T763 S817 S826 S870 S878 S923 T1043 T1050 T1053 T1065 S1067 S1071 S1081 S2083 protein RNA SCNV methylation LUAD T326 T329 S330 T398 T400 S407 S550 S553 S560 S575 Y583 S747 T758 S762 T763 S817 S826 S870 S878 S923 T1043 T1050 T1053 T1065 S1067 S1071 S1081 S2083 protein RNA SCNV methylation OV T326 T329 S330 T398 T400 S407 S550 S553 S560 S575 Y583 S747 T758 S762 T763 S817 S826 S870 S878 S923 T1043 T1050 T1053 T1065 S1067 S1071 S1081 S2083 protein RNA SCNV methylation PDAC T326 T329 S330 T398 T400 S407 S550 S553 S560 S575 Y583 S747 T758 S762 T763 S817 S826 S870 S878 S923 T1043 T1050 T1053 T1065 S1067 S1071 S1081 S2083 protein RNA SCNV methylation UCEC T326 T329 S330 T398 T400 S407 S550 S553 S560 S575 Y583 S747 T758 S762 T763 S817 S826 S870 S878 S923 T1043 T1050 T1053 T1065 S1067 S1071 S1081 S2083 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T326
T329
S330
T398
T400
S407
S550
S553
S560
S575
Y583
S747
T758
S762
T763
S817
S826
S870
S878
S923
S1003
T1043
T1050
T1053
T1065
S1067
S1071
S1081
S2083
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
T326
T329
S330
T398
T400
S407
S550
S553
S560
S575
Y583
S747
T758
S762
T763
S817
S826
S870
S878
S923
S1003
T1043
T1050
T1053
T1065
S1067
S1071
S1081
S2083
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.