GJA1: gap junction protein alpha 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2ll2 chain A
7f92 chain A
7f92 chain B
7f92 chain C
7f92 chain D
7f92 chain E
7f92 chain F
7f92 chain G
7f92 chain H
7f92 chain I
7f92 chain J
7f92 chain K
7f92 chain L
7f93 chain A
7f93 chain B
7f93 chain C
7f93 chain D
7f93 chain E
7f93 chain F
7f93 chain G
7f93 chain H
7f93 chain I
7f93 chain J
7f93 chain K
7f93 chain L
7f94 chain A
7f94 chain B
7f94 chain C
7f94 chain D
7f94 chain E
7f94 chain F
7f94 chain G
7f94 chain H
7f94 chain I
7f94 chain J
7f94 chain K
7f94 chain L
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S5 ___MGDWS ALGKLLD 3 147 - - - - - - 81 - - - 29 28 5 4 - - - - - - Y247 VKGKSDPY HATSGAL 1 9 - - - - - - 9 - - - - - - - - - - - - - T250 KSDPYHAT SGALSPA 3 58 6 - - - - - 44 - 4 4 - - - - - - - - - - S251 SDPYHATS GALSPAK 6 418 9 - - - - - 99 - 58 37 64 57 - - 58 11 - - 11 14 S255 HATSGALS PAKDCGS 8 631 30 - - - - - 90 - 102 59 98 89 8 8 70 16 9 4 37 11 S262 SPAKDCGS QKYAYFN 1 80 - - - - - - 80 - - - - - - - - - - - - - Y265 KDCGSQKY AYFNGCS 4 60 - - - - - - 18 - 5 3 10 8 - - - - - - 5 11 S272 YAYFNGCS SPTAPLS 3 62 - - - - - - 18 - 17 8 10 9 - - - - - - - - S273 AYFNGCSS PTAPLSP 5 193 24 - - - - - 89 - 16 11 - - 8 8 - - - - 30 7 T275 FNGCSSPT APLSPMS 9 751 55 - 40 23 - - 99 - 108 62 79 69 41 37 24 8 26 13 53 14
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S5 ___MGDWS ALGKLLD -1.3e-16 - - - - - -1.3e-16 - - - - Y247 VKGKSDPY HATSGAL - - - - - - - - - - - T250 KSDPYHAT SGALSPA - - - - - - - - - - - S251 SDPYHATS GALSPAK 0.077 - - - - 0.03 0.033 - -0.22 - - S255 HATSGALS PAKDCGS 0.011 - - - - 2.8e-8 0.62 - 0.78 - -0.21 S262 SPAKDCGS QKYAYFN - - - - - - - - - - - Y265 KDCGSQKY AYFNGCS - - - - - - - - - - - S272 YAYFNGCS SPTAPLS - - - - - - - - - - - S273 AYFNGCSS PTAPLSP - - - - - - - - - - - T275 FNGCSSPT APLSPMS 3.3e-8 - 1.6e-9 - - 1.1e-5 7.3e-9 -1.1e-3 - 2.4e-5 -2.8e-4
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S5
Y247
T250
S251
S255
S262
Y265
S272
S273
T275
S279
S282
T290
S296
S297
S306
Y313
S314
S325
T326
S328
S330
S344
S364
S365
S368
S369
S372
S373
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S5 Y247 T250 S251 S255 S262 Y265 S272 S273 T275 S279 S282 T290 S296 S297 S306 Y313 S314 S325 T326 S328 S330 S344 S364 S365 S368 S369 S372 S373 protein RNA SCNV methylation CCRCC S5 Y247 T250 S251 S255 S262 Y265 S272 S273 T275 S279 S282 T290 S296 S297 S306 Y313 S314 S325 T326 S328 S330 S344 S364 S365 S368 S369 S372 S373 protein RNA SCNV methylation COAD S5 Y247 T250 S251 S255 S262 Y265 S272 S273 T275 S279 S282 T290 S296 S297 S306 Y313 S314 S325 T326 S328 S330 S344 S364 S365 S368 S369 S372 S373 protein RNA SCNV methylation GBM S5 Y247 T250 S251 S255 S262 Y265 S272 S273 T275 S279 S282 T290 S296 S297 S306 Y313 S314 S325 T326 S328 S330 S344 S364 S365 S368 S369 S372 S373 protein RNA SCNV methylation HNSCC S5 Y247 T250 S251 S255 S262 Y265 S272 S273 T275 S279 S282 T290 S296 S297 S306 Y313 S314 S325 T326 S328 S330 S344 S364 S365 S368 S369 S372 S373 protein RNA SCNV methylation LSCC S5 Y247 T250 S251 S255 S262 Y265 S272 S273 T275 S279 S282 T290 S296 S297 S306 Y313 S314 S325 T326 S328 S330 S344 S364 S365 S368 S369 S372 S373 protein RNA SCNV methylation LUAD S5 Y247 T250 S251 S255 S262 Y265 S272 S273 T275 S279 S282 T290 S296 S297 S306 Y313 S314 S325 T326 S328 S330 S344 S364 S365 S368 S369 S372 S373 protein RNA SCNV methylation OV S5 Y247 T250 S251 S255 S262 Y265 S272 S273 T275 S279 S282 T290 S296 S297 S306 Y313 S314 S325 T326 S328 S330 S344 S364 S365 S368 S369 S372 S373 protein RNA SCNV methylation PDAC S5 Y247 T250 S251 S255 S262 Y265 S272 S273 T275 S279 S282 T290 S296 S297 S306 Y313 S314 S325 T326 S328 S330 S344 S364 S365 S368 S369 S372 S373 protein RNA SCNV methylation UCEC S5 Y247 T250 S251 S255 S262 Y265 S272 S273 T275 S279 S282 T290 S296 S297 S306 Y313 S314 S325 T326 S328 S330 S344 S364 S365 S368 S369 S372 S373 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S5
Y247
T250
S251
S255
S262
Y265
S272
S273
T275
S279
S282
T290
S296
S297
S306
Y313
S314
S325
T326
S328
S330
S344
S364
S365
S368
S369
S372
S373
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S5
Y247
T250
S251
S255
S262
Y265
S272
S273
T275
S279
S282
T290
S296
S297
S306
Y313
S314
S325
T326
S328
S330
S344
S364
S365
S368
S369
S372
S373
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.