DDAH1: dimethylarginine dimethylaminohydrolase 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2jai chain A
2jai chain B
2jaj chain A
2jaj chain B
3i2e chain A
3i2e chain B
3i4a chain A
3i4a chain B
3p8e chain A
3p8e chain B
3p8p chain A
3p8p chain B
6dge chain A
6szp chain A
6szq chain A
6szq chain B
6szq chain C
6szq chain D
6szq chain E
6szq chain F
7usz chain A
7usz chain B
7ut0 chain A
7ut0 chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S56 LYVGVLGS KLGLQVV 8 395 22 - 90 68 - - 90 - - - 5 5 27 24 7 1 31 17 8 - S193 IAIGSSES AQKALKI 2 17 - - 4 4 - - 9 - - - - - - - - - - - - - T238 GHVLLHRT PEEYPES 1 9 - - - - - - 9 - - - - - - - - - - - - - S261 DHMLIPVS MSELEKV 5 279 8 - 78 64 - - 99 - - - - - 8 8 - - 11 3 - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S56 LYVGVLGS KLGLQVV -1e-19 - -2.2e-21 - - - - -0.27 - -2.6e-7 - S193 IAIGSSES AQKALKI - - - - - - - - - - - T238 GHVLLHRT PEEYPES - - - - - - - - - - - S261 DHMLIPVS MSELEKV -4.7e-19 - -4.7e-19 - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S56
S193
T238
S261
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S56 S193 T238 S261 protein RNA SCNV methylation CCRCC S56 S193 T238 S261 protein RNA SCNV methylation COAD S56 S193 T238 S261 protein RNA SCNV methylation GBM S56 S193 T238 S261 protein RNA SCNV methylation HNSCC S56 S193 T238 S261 protein RNA SCNV methylation LSCC S56 S193 T238 S261 protein RNA SCNV methylation LUAD S56 S193 T238 S261 protein RNA SCNV methylation OV S56 S193 T238 S261 protein RNA SCNV methylation PDAC S56 S193 T238 S261 protein RNA SCNV methylation UCEC S56 S193 T238 S261 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S56
S193
T238
S261
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S56
S193
T238
S261
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.