XPC: XPC complex subunit, DNA damage recognition and repair factor
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2a4j chain B
2ggm chain C
2ggm chain D
2obh chain C
2obh chain D
2rvb chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
Loading, please wait
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S61 GKRKRGCS HPGGSAD 8 480 8 - - - 42 47 62 - 58 34 15 14 - - 33 10 88 35 21 13 S66 GCSHPGGS ADGPAKK 5 200 25 - 61 43 - - - - - - 25 23 10 7 - - - - 6 - S94 VIKDEALS DGDDLRD 10 1536 122 - 103 80 97 100 99 - 108 62 108 99 110 101 68 17 105 44 95 18 T117 HHLKRGAT MNEDSNE 2 14 6 - - - - - - - - - - - - - - - - - 5 3 S122 GATMNEDS NEEEEES 6 130 6 - 4 4 4 5 - - - - 29 27 8 8 - - - - 23 12 S129 SNEEEEES ENDWEEV 6 257 7 - 21 17 54 51 - - - - 29 27 8 8 - - - - 23 12 S140 WEEVEELS EPVLGDV 2 12 6 - - - - - - - - - - - - - - - - - 6 - T169 PVEIEIET PEQAKTR 5 166 61 - 20 20 - - - - 16 11 15 14 5 4 - - - - - - S346 LTADPGGS SETSSQV 3 41 9 - - - - - - - - - - - - - - - 6 2 13 11 S347 TADPGGSS ETSSQVL 10 936 72 - 58 46 28 34 90 - 29 18 63 59 101 93 29 5 91 39 74 7
Tumor and normal comparison
Loading, please wait
Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S61 GKRKRGCS HPGGSAD -9e-27 - - -6.4e-7 - -5.2e-11 - - -7.7e-3 -3.8e-9 -1.2e-4 S66 GCSHPGGS ADGPAKK -8.5e-3 - -1.1e-6 - - - 0.25 - - - - S94 VIKDEALS DGDDLRD -8.1e-60 - -1.1e-17 0.47 - -9.6e-19 -2.6e-26 -5.6e-16 0.58 -1.8e-10 -8.9e-7 T117 HHLKRGAT MNEDSNE - - - - - - - - - - - S122 GATMNEDS NEEEEES -7.5e-5 - - - - - -0.3 - - - -4.8e-6 S129 SNEEEEES ENDWEEV -6.2e-4 - -0.15 0.85 - - -0.3 - - - -4.8e-6 S140 WEEVEELS EPVLGDV - - - - - - - - - - - T169 PVEIEIET PEQAKTR -0.49 - -0.49 - - - - - - - - S346 LTADPGGS SETSSQV - - - - - - - - - - - S347 TADPGGSS ETSSQVL -7e-8 - -4.9e-8 0.22 - -4.7e-4 -1.6e-4 -6.3e-6 - 4.8e-3 -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
Loading, please wait
all sites
S61
S66
S94
T117
S122
S129
S140
T169
S346
S347
T349
S350
S351
S394
S397
S398
S399
S426
S429
S503
S504
S505
S506
S515
S883
S884
T890
S891
S892
S903
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S61 S66 S94 T117 S122 S129 S140 T169 S346 S347 T349 S350 S351 S394 S397 S398 S399 S426 S503 S504 S505 S506 S515 S883 S884 T890 S891 S892 S903 protein RNA SCNV methylation CCRCC S61 S66 S94 T117 S122 S129 S140 T169 S346 S347 T349 S350 S351 S394 S397 S398 S399 S426 S503 S504 S505 S506 S515 S883 S884 T890 S891 S892 S903 protein RNA SCNV methylation COAD S61 S66 S94 T117 S122 S129 S140 T169 S346 S347 T349 S350 S351 S394 S397 S398 S399 S426 S503 S504 S505 S506 S515 S883 S884 T890 S891 S892 S903 protein RNA SCNV methylation GBM S61 S66 S94 T117 S122 S129 S140 T169 S346 S347 T349 S350 S351 S394 S397 S398 S399 S426 S503 S504 S505 S506 S515 S883 S884 T890 S891 S892 S903 protein RNA SCNV methylation HNSCC S61 S66 S94 T117 S122 S129 S140 T169 S346 S347 T349 S350 S351 S394 S397 S398 S399 S426 S503 S504 S505 S506 S515 S883 S884 T890 S891 S892 S903 protein RNA SCNV methylation LSCC S61 S66 S94 T117 S122 S129 S140 T169 S346 S347 T349 S350 S351 S394 S397 S398 S399 S426 S503 S504 S505 S506 S515 S883 S884 T890 S891 S892 S903 protein RNA SCNV methylation LUAD S61 S66 S94 T117 S122 S129 S140 T169 S346 S347 T349 S350 S351 S394 S397 S398 S399 S426 S503 S504 S505 S506 S515 S883 S884 T890 S891 S892 S903 protein RNA SCNV methylation OV S61 S66 S94 T117 S122 S129 S140 T169 S346 S347 T349 S350 S351 S394 S397 S398 S399 S426 S503 S504 S505 S506 S515 S883 S884 T890 S891 S892 S903 protein RNA SCNV methylation PDAC S61 S66 S94 T117 S122 S129 S140 T169 S346 S347 T349 S350 S351 S394 S397 S398 S399 S426 S503 S504 S505 S506 S515 S883 S884 T890 S891 S892 S903 protein RNA SCNV methylation UCEC S61 S66 S94 T117 S122 S129 S140 T169 S346 S347 T349 S350 S351 S394 S397 S398 S399 S426 S503 S504 S505 S506 S515 S883 S884 T890 S891 S892 S903 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S61
S66
S94
T117
S122
S129
S140
T169
S346
S347
T349
S350
S351
S394
S397
S398
S399
S426
S429
S503
S504
S505
S506
S515
S883
S884
T890
S891
S892
S903
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S61
S66
S94
T117
S122
S129
S140
T169
S346
S347
T349
S350
S351
S394
S397
S398
S399
S426
S429
S503
S504
S505
S506
S515
S883
S884
T890
S891
S892
S903
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.