DEPTOR: DEP domain containing MTOR interacting protein
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
7dkl chain A
7owg chain O
7pe7 chain I
7pe7 chain J
7pe8 chain I
7pe9 chain I
7pea chain I
7pea chain J
7peb chain I
7pec chain I
7ped chain A
7ped chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T59 DRRHHLKT YPNCFVA 2 50 - - - - - - - - - - - - - - - - 7 2 41 - S145 RLYEKLMS PENTLLQ 1 35 - - - - - - - - - - - - - - - - - - 30 5 S235 MELLNEKS PSSQETH 5 92 - - - - 9 9 18 - 11 7 - - - - 7 2 - - 25 4 S237 LLNEKSPS SQETHDS 1 8 8 - - - - - - - - - - - - - - - - - - - S238 LNEKSPSS QETHDSP 1 14 14 - - - - - - - - - - - - - - - - - - - S244 SSQETHDS PFCLRKQ 5 439 - - - - 80 73 81 - - - - - - - 54 12 42 19 64 14 S252 PFCLRKQS HDNRKST 1 12 - - - - - - - - - - - - - - - - 8 4 - - S258 QSHDNRKS TSFMSVS 9 542 34 - 24 23 - - 44 - 39 25 49 44 34 33 30 5 53 25 64 16 S260 HDNRKSTS FMSVSPS 10 1134 95 - 46 44 57 59 72 - 58 33 73 67 92 85 83 19 98 40 95 18 S263 RKSTSFMS VSPSKEI 5 73 17 - 12 12 - - - - - - 10 8 - - 7 1 - - 6 -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T59 DRRHHLKT YPNCFVA - - - - - - - - - - - S145 RLYEKLMS PENTLLQ - - - - - - - - - - - S235 MELLNEKS PSSQETH - - - - - - - - - - - S237 LLNEKSPS SQETHDS - - - - - - - - - - - S238 LNEKSPSS QETHDSP - - - - - - - - - - - S244 SSQETHDS PFCLRKQ -0.042 - - -2.7e-8 - - - - 0.26 0.65 -0.93 S252 PFCLRKQS HDNRKST - - - - - - - - - - - S258 QSHDNRKS TSFMSVS -0.016 - 0.051 - - -9.7e-8 -5.7e-10 0.66 - 3.8e-3 0.71 S260 HDNRKSTS FMSVSPS -0.8 - 0.11 -1.1e-7 - -7.5e-12 -0.52 3.5e-12 -0.89 9.5e-5 -0.84 S263 RKSTSFMS VSPSKEI - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T59
S145
S235
S237
S238
S244
S252
S258
S260
S263
S265
S267
S279
S280
S282
S283
S286
S287
Y289
S291
S292
S293
T295
S297
S298
S299
T315
S316
T321
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T59 S145 S235 S237 S238 S244 S252 S258 S260 S263 S265 S279 S280 S282 S283 S286 S287 Y289 S291 S292 S293 T295 S297 S298 S299 T315 S316 T321 protein RNA SCNV methylation CCRCC T59 S145 S235 S237 S238 S244 S252 S258 S260 S263 S265 S279 S280 S282 S283 S286 S287 Y289 S291 S292 S293 T295 S297 S298 S299 T315 S316 T321 protein RNA SCNV methylation COAD T59 S145 S235 S237 S238 S244 S252 S258 S260 S263 S265 S279 S280 S282 S283 S286 S287 Y289 S291 S292 S293 T295 S297 S298 S299 T315 S316 T321 protein RNA SCNV methylation GBM T59 S145 S235 S237 S238 S244 S252 S258 S260 S263 S265 S279 S280 S282 S283 S286 S287 Y289 S291 S292 S293 T295 S297 S298 S299 T315 S316 T321 protein RNA SCNV methylation HNSCC T59 S145 S235 S237 S238 S244 S252 S258 S260 S263 S265 S279 S280 S282 S283 S286 S287 Y289 S291 S292 S293 T295 S297 S298 S299 T315 S316 T321 protein RNA SCNV methylation LSCC T59 S145 S235 S237 S238 S244 S252 S258 S260 S263 S265 S279 S280 S282 S283 S286 S287 Y289 S291 S292 S293 T295 S297 S298 S299 T315 S316 T321 protein RNA SCNV methylation LUAD T59 S145 S235 S237 S238 S244 S252 S258 S260 S263 S265 S279 S280 S282 S283 S286 S287 Y289 S291 S292 S293 T295 S297 S298 S299 T315 S316 T321 protein RNA SCNV methylation OV T59 S145 S235 S237 S238 S244 S252 S258 S260 S263 S265 S279 S280 S282 S283 S286 S287 Y289 S291 S292 S293 T295 S297 S298 S299 T315 S316 T321 protein RNA SCNV methylation PDAC T59 S145 S235 S237 S238 S244 S252 S258 S260 S263 S265 S279 S280 S282 S283 S286 S287 Y289 S291 S292 S293 T295 S297 S298 S299 T315 S316 T321 protein RNA SCNV methylation UCEC T59 S145 S235 S237 S238 S244 S252 S258 S260 S263 S265 S279 S280 S282 S283 S286 S287 Y289 S291 S292 S293 T295 S297 S298 S299 T315 S316 T321 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T59
S145
S235
S237
S238
S244
S252
S258
S260
S263
S265
S267
S279
S280
S282
S283
S286
S287
Y289
S291
S292
S293
T295
S297
S298
S299
T315
S316
T321
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
T59
S145
S235
S237
S238
S244
S252
S258
S260
S263
S265
S267
S279
S280
S282
S283
S286
S287
Y289
S291
S292
S293
T295
S297
S298
S299
T315
S316
T321
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.