CSF1R: colony stimulating factor 1 receptor
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2i0v chain A
2i0y chain A
2i1m chain A
2ogv chain A
3bea chain A
3dpk chain A
3krj chain A
3krl chain A
3lcd chain A
3lco chain A
4dkd chain C
4hw7 chain A
4liq chain E
4r7h chain A
4r7i chain A
4wrl chain A
4wrl chain C
4wrm chain A
6ig8 chain A
6n33 chain A
6t2w chain A
6wxj chain A
7mfc chain A
7tnh chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
Y699 DPEGGVDY KNIHLEK 3 34 - - - - - - - - - - 10 10 4 4 - - 5 1 - - S713 KKYVRRDS GFSSQGV 5 150 17 - - - - - 63 - - - 19 16 5 4 20 6 - - - - S736 VSTSSNDS FSEQDLD 1 10 - - - - - - - - - - 5 5 - - - - - - - - Y809 DIMNDSNY IVKGNAR 1 10 - - - - - - - - - - 5 5 - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Y699 DPEGGVDY KNIHLEK - - - - - - - - - - - S713 KKYVRRDS GFSSQGV - - - - - - - - - - - S736 VSTSSNDS FSEQDLD - - - - - - - - - - - Y809 DIMNDSNY IVKGNAR - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
Y699
S713
S736
Y809
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA Y699 S713 S736 Y809 protein RNA SCNV methylation CCRCC Y699 S713 S736 Y809 protein RNA SCNV methylation COAD Y699 S713 S736 Y809 protein RNA SCNV methylation GBM Y699 S713 S736 Y809 protein RNA SCNV methylation HNSCC Y699 S713 S736 Y809 protein RNA SCNV methylation LSCC Y699 S713 S736 Y809 protein RNA SCNV methylation LUAD Y699 S713 S736 Y809 protein RNA SCNV methylation OV Y699 S713 S736 Y809 protein RNA SCNV methylation PDAC Y699 S713 S736 Y809 protein RNA SCNV methylation UCEC Y699 S713 S736 Y809 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
Y699
S713
S736
Y809
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
Y699
S713
S736
Y809
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.