KCNMA1: potassium calcium-activated channel subfamily M alpha 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2k44 chain A
3mt5 chain A
3naf chain A
6nd0 chain A
6nd0 chain B
6nd0 chain C
6nd0 chain D
6v22 chain A
6v22 chain B
6v22 chain C
6v22 chain D
6v35 chain A
6v35 chain B
6v35 chain C
6v35 chain D
6v38 chain A
6v38 chain B
6v38 chain C
6v38 chain D
6v3g chain A
6v3g chain B
6v3g chain C
6v3g chain D
6v5a chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T763 FEDEQPST LSPKKKQ 1 8 - - - - - - 8 - - - - - - - - - - - - - S765 DEQPSTLS PKKKQRN 1 18 - - - - - - 18 - - - - - - - - - - - - - S778 RNGGMRNS PNTSPKL 8 371 48 - 45 33 - - 53 - 27 17 5 4 42 41 - - 14 6 30 6 T781 GMRNSPNT SPKLMRH 7 230 17 - 8 8 - - - - 6 4 78 71 5 4 - - 2 1 26 - S782 MRNSPNTS PKLMRHD 7 267 - - 7 7 - - 99 - 11 7 4 4 8 9 - - 29 13 63 6 S966 IGVLQANS QGFTPPG 1 9 - - - - - - 9 - - - - - - - - - - - - - T970 QANSQGFT PPGMDRS 1 46 - - - - - - 46 - - - - - - - - - - - - - S977 TPPGMDRS SPDNSPV 1 25 - - - - - - 25 - - - - - - - - - - - - - S978 PPGMDRSS PDNSPVH 2 158 - - - - - - 64 - - - - - - - 76 18 - - - - S982 DRSSPDNS PVHGMLR 1 63 - - - - - - 63 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T763 FEDEQPST LSPKKKQ - - - - - - - - - - - S765 DEQPSTLS PKKKQRN - - - - - - - - - - - S778 RNGGMRNS PNTSPKL 1.1e-8 - 1.9e-9 - - 0.98 - 1.1e-4 - - - T781 GMRNSPNT SPKLMRH 5.0e-5 - - - - - 5.0e-5 - - - - S782 MRNSPNTS PKLMRHD -0.092 - - - - - - - - -0.092 - S966 IGVLQANS QGFTPPG - - - - - - - - - - - T970 QANSQGFT PPGMDRS - - - - - - - - - - - S977 TPPGMDRS SPDNSPV - - - - - - - - - - - S978 PPGMDRSS PDNSPVH -4.1e-3 - - - - - - - -4.1e-3 - - S982 DRSSPDNS PVHGMLR - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T763
S765
S778
T781
S782
S966
T970
S977
S978
S982
Y1086
S1087
T1088
S1188
S1193
S1196
S1198
S1199
S1204
S1205
S1208
S1211
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T763 S765 S778 T781 S782 S966 T970 S977 S978 S982 Y1086 S1087 T1088 S1188 S1193 S1196 S1198 S1199 S1204 S1205 S1208 S1211 protein RNA SCNV methylation CCRCC T763 S765 S778 T781 S782 S966 T970 S977 S978 S982 Y1086 S1087 T1088 S1188 S1193 S1196 S1198 S1199 S1204 S1205 S1208 S1211 protein RNA SCNV methylation COAD T763 S765 S778 T781 S782 S966 T970 S977 S978 S982 Y1086 S1087 T1088 S1188 S1193 S1196 S1198 S1199 S1204 S1205 S1208 S1211 protein RNA SCNV methylation GBM T763 S765 S778 T781 S782 S966 T970 S977 S978 S982 Y1086 S1087 T1088 S1188 S1193 S1196 S1198 S1199 S1204 S1205 S1208 S1211 protein RNA SCNV methylation HNSCC T763 S765 S778 T781 S782 S966 T970 S977 S978 S982 Y1086 S1087 T1088 S1188 S1193 S1196 S1198 S1199 S1204 S1205 S1208 S1211 protein RNA SCNV methylation LSCC T763 S765 S778 T781 S782 S966 T970 S977 S978 S982 Y1086 S1087 T1088 S1188 S1193 S1196 S1198 S1199 S1204 S1205 S1208 S1211 protein RNA SCNV methylation LUAD T763 S765 S778 T781 S782 S966 T970 S977 S978 S982 Y1086 S1087 T1088 S1188 S1193 S1196 S1198 S1199 S1204 S1205 S1208 S1211 protein RNA SCNV methylation OV T763 S765 S778 T781 S782 S966 T970 S977 S978 S982 Y1086 S1087 T1088 S1188 S1193 S1196 S1198 S1199 S1204 S1205 S1208 S1211 protein RNA SCNV methylation PDAC T763 S765 S778 T781 S782 S966 T970 S977 S978 S982 Y1086 S1087 T1088 S1188 S1193 S1196 S1198 S1199 S1204 S1205 S1208 S1211 protein RNA SCNV methylation UCEC T763 S765 S778 T781 S782 S966 T970 S977 S978 S982 Y1086 S1087 T1088 S1188 S1193 S1196 S1198 S1199 S1204 S1205 S1208 S1211 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T763
S765
S778
T781
S782
S966
T970
S977
S978
S982
Y1086
S1087
T1088
S1188
S1193
S1196
S1198
S1199
S1204
S1205
S1208
S1211
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
T763
S765
S778
T781
S782
S966
T970
S977
S978
S982
Y1086
S1087
T1088
S1188
S1193
S1196
S1198
S1199
S1204
S1205
S1208
S1211
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.