- KIT:
- KIT proto-oncogene, receptor tyrosine kinase
Lollipop plot
Phosphosites location and occurrence
Structure
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Site
| Sequence | Cohorts | Total | T | N | T | N | T | N | T | N | T | N | T | N | T | N | T | N | T | N | T | N |
S688 | FLRRKRDSFICSKQE | 2 | 32 | - | - | 11 | 11 | - | - | - | - | - | - | 5 | 5 | - | - | - | - | - | - | - | - |
Y703 | DHAEAALYKNLLHSK | 2 | 15 | 9 | - | 3 | 3 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
S746 | RRSVRIGSYIERDVT | 8 | 715 | - | - | - | - | 65 | 70 | 53 | - | 52 | 29 | 73 | 68 | 18 | 15 | 62 | 15 | 105 | 44 | 35 | 11 |
S943 | YSNLANCSPNRQKPV | 3 | 126 | - | - | - | - | - | - | 90 | - | - | - | 5 | 4 | - | - | 22 | 5 | - | - | - | - |
S954 | QKPVVDHSVRINSVG | 5 | 149 | - | - | 3 | 3 | 16 | 28 | - | - | - | - | 20 | 19 | 21 | 20 | - | - | 13 | 6 | - | - |
S959 | DHSVRINSVGSTASS | 6 | 206 | - | - | - | - | 20 | 16 | 45 | - | - | - | 4 | 4 | 10 | 8 | - | - | 56 | 21 | 11 | 11 |
S967 | VGSTASSSQPLLVHD | 6 | 145 | 15 | - | 15 | 15 | 5 | 4 | 9 | - | - | - | 39 | 35 | 4 | 4 | - | - | - | - | - | - |
Tumor and normal comparison
Site
| Sequence | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
---|---|---|---|---|---|---|---|---|---|---|---|---|
S688 | FLRRKRDSFICSKQE | - | - | - | - | - | - | - | - | - | - | - |
Y703 | DHAEAALYKNLLHSK | - | - | - | - | - | - | - | - | - | - | - |
S746 | RRSVRIGSYIERDVT | -6.3e-48 | - | - | -2.9e-19 | - | -1.4e-6 | -1.3e-21 | - | -1.5e-7 | -1.4e-3 | -1.4e-4 |
S943 | YSNLANCSPNRQKPV | - | - | - | - | - | - | - | - | - | - | - |
S954 | QKPVVDHSVRINSVG | -1.9e-7 | - | - | - | - | - | -2.4e-3 | -1.5e-5 | - | - | - |
S959 | DHSVRINSVGSTASS | -3.6e-7 | - | - | -2.2e-3 | - | - | - | - | - | -3.6e-5 | - |
S967 | VGSTASSSQPLLVHD | 0.041 | - | - | - | - | - | 0.041 | - | - | - | - |
Phenotype and mutation association
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Phenotype | Site | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
No matching records found |
Cis-association
Kinase association
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Kinase | Site | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
No matching records found |
Phosphatase association
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphatase | Site | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
No matching records found |