ACE: angiotensin I converting enzyme
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1o86 chain A
1o8a chain A
1uze chain A
1uzf chain A
2c6f chain A
2c6f chain B
2c6n chain A
2c6n chain B
2iul chain A
2iux chain A
2oc2 chain A
2xy9 chain A
2xyd chain A
2xyd chain B
2ydm chain A
3bkk chain A
3bkl chain A
3l3n chain A
3nxq chain A
3nxq chain B
4aph chain A
4apj chain A
4bxk chain A
4bxk chain B
4bzr chain A
4bzs chain A
4bzs chain B
4c2n chain A
4c2o chain A
4c2p chain A
4c2q chain A
4c2r chain A
4ca5 chain A
4ca6 chain A
4ca6 chain B
4ufa chain A
4ufa chain B
4ufb chain A
4ufb chain B
4ufb chain C
4ufb chain D
5am8 chain A
5am8 chain B
5am8 chain C
5am8 chain D
5am9 chain A
5am9 chain B
5am9 chain C
5am9 chain D
5ama chain A
5ama chain B
5ama chain C
5ama chain D
5amb chain A
5amb chain B
5amc chain A
5amc chain B
6en5 chain A
6en5 chain B
6en5 chain C
6en5 chain D
6en6 chain A
6en6 chain B
6en6 chain C
6en6 chain D
6f9r chain A
6f9r chain B
6f9t chain A
6f9u chain A
6f9v chain A
6f9v chain B
6h5w chain A
6h5x chain A
6h5x chain B
6qs1 chain A
6qs1 chain B
6tt1 chain A
6tt1 chain B
6tt3 chain A
6tt3 chain B
6tt4 chain A
6tt4 chain B
6zpq chain A
6zpq chain B
6zpq chain C
6zpq chain D
6zpt chain A
6zpt chain B
6zpt chain C
6zpt chain D
6zpu chain A
7q24 chain A
7q24 chain B
7q25 chain A
7q25 chain B
7q26 chain A
7q26 chain B
7q27 chain A
7q28 chain A
7q29 chain A
7q3y chain A
7q49 chain A
7q4c chain A
7q4d chain A
7q4d chain B
7q4e chain A
7z6z chain A
7z6z chain B
7z70 chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S1299 SHGPQFGS EVELRHS 2 175 - - - - - - - - - - 55 51 37 32 - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S1299 SHGPQFGS EVELRHS -4e-11 - - - - - -8.8e-5 -6e-8 - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S1299
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S1299 protein RNA SCNV methylation CCRCC S1299 protein RNA SCNV methylation COAD S1299 protein RNA SCNV methylation GBM S1299 protein RNA SCNV methylation HNSCC S1299 protein RNA SCNV methylation LSCC S1299 protein RNA SCNV methylation LUAD S1299 protein RNA SCNV methylation OV S1299 protein RNA SCNV methylation PDAC S1299 protein RNA SCNV methylation UCEC S1299 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S1299
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S1299
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.