Protein: ENSP00000292807
Gene: AP2M1

LinkedOmicsKB © 2022-2023 Zhang Lab

AP2M1:
adaptor related protein complex 2 subunit mu 1

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S45HARQQVRSPVTNIAR8783--7759--99-61349385706533824124716
S54VTNIARTSFFHVKRS117------------------17-
S61SFFHVKRSNIWLAAV145------45-------------
S149HQTKEEQSQITSQVT117--98----------------
S153EEQSQITSQVTGQIG7182--3619--9-6419171212--249105
T156SQITSQVTGQIGWRR8383--44--90-11724234471152158416
T229IEKQGKGTADETSKS236------27------------9
S236TADETSKSGKQSIAI217--------------7154--
S240TSKSGKQSIAIDDCT223--44--------------132
S314IKSNFKPSLLAQKIE263--54--54-------------
Showing 1 to 10 of 11 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S45HARQQVRSPVTNIAR1.0e-5-7.5e-3--3.1e-51.1e-60.47--0.78-0.18
S54VTNIARTSFFHVKRS-----------
S61SFFHVKRSNIWLAAV-----------
S149HQTKEEQSQITSQVT-----------
S153EEQSQITSQVTGQIG0.72-0.72--------
T156SQITSQVTGQIGWRR-0.3------0.31--0.11-0.39
T229IEKQGKGTADETSKS-----------
S236TADETSKSGKQSIAI-----------
S240TSKSGKQSIAIDDCT-----------
S314IKSNFKPSLLAQKIE-----------
Showing 1 to 10 of 11 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS45S54S61S149S153T156T229S236S240S314S347proteinRNASCNVmethylationCCRCCS45S54S61S149S153T156T229S236S240S314S347proteinRNASCNVmethylationCOADS45S54S61S149S153T156T229S236S240S314S347proteinRNASCNVmethylationGBMS45S54S61S149S153T156T229S236S240S314S347proteinRNASCNVmethylationHNSCCS45S54S61S149S153T156T229S236S240S314S347proteinRNASCNVmethylationLSCCS45S54S61S149S153T156T229S236S240S314S347proteinRNASCNVmethylationLUADS45S54S61S149S153T156T229S236S240S314S347proteinRNASCNVmethylationOVS45S54S61S149S153T156T229S236S240S314S347proteinRNASCNVmethylationPDACS45S54S61S149S153T156T229S236S240S314S347proteinRNASCNVmethylationUCECS45S54S61S149S153T156T229S236S240S314S347proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.