ADCY9: adenylate cyclase 9
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S38 KINPKQLS SNSHPKH 5 199 - - - - 21 32 71 - 17 11 - - - - 36 6 4 1 - - S52 HCKYSISS SCSSSGD 1 10 - - - - - - - - - - 5 5 - - - - - - - - S53 CKYSISSS CSSSGDS 1 10 - - - - - - - - - - 5 5 - - - - - - - - S55 YSISSSCS SSGDSGG 1 10 - - - - - - - - - - 5 5 - - - - - - - - S56 SISSSCSS SGDSGGV 1 9 - - - - - - 9 - - - - - - - - - - - - - S354 MKQGDEES ENSVKRH 9 393 6 - 35 33 13 14 27 - 32 16 24 22 80 72 - - 9 3 5 2 S357 GDEESENS VKRHATS 8 193 9 - 24 16 12 15 35 - - - 10 10 10 8 - - 26 10 5 3 S582 RAKESRCS CAEALLS 3 143 - - - - - - - - - - 38 38 30 29 - - - - 5 3 S610 PRGQGTAS SGNVSDL 5 165 - - - - 15 20 36 - - - - - 5 4 - - 16 8 45 16 S611 RGQGTASS GNVSDLA 9 634 59 - 77 59 18 18 - - 37 22 68 64 55 47 12 4 51 23 18 2
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S38 KINPKQLS SNSHPKH -0.038 - - -0.038 - - - - - - - S52 HCKYSISS SCSSSGD - - - - - - - - - - - S53 CKYSISSS CSSSGDS - - - - - - - - - - - S55 YSISSSCS SSGDSGG - - - - - - - - - - - S56 SISSSCSS SGDSGGV - - - - - - - - - - - S354 MKQGDEES ENSVKRH -7.5e-11 - -7.3e-11 - - 0.67 -0.033 -1.6e-6 - - - S357 GDEESENS VKRHATS -0.45 - 0.095 - - - - - - -6.2e-3 - S582 RAKESRCS CAEALLS -6.3e-16 - - - - - -2.8e-10 -3e-7 - - - S610 PRGQGTAS SGNVSDL -1.2e-7 - - - - - - - - - -1.2e-7 S611 RGQGTASS GNVSDLA -0.073 - -5e-10 - - 4.8e-3 0.087 0.18 - -2.6e-4 -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S38
S52
S53
S55
S56
S354
S357
S582
S610
S611
S615
S632
S661
S688
T690
S691
S706
S710
S1257
S1259
S1269
S1273
T1275
S1292
S1295
S1307
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S38 S52 S53 S55 S56 S354 S357 S582 S610 S611 S615 S632 S661 S688 T690 S691 S706 S710 S1257 S1259 S1269 S1273 T1275 S1292 S1295 S1307 protein RNA SCNV methylation CCRCC S38 S52 S53 S55 S56 S354 S357 S582 S610 S611 S615 S632 S661 S688 T690 S691 S706 S710 S1257 S1259 S1269 S1273 T1275 S1292 S1295 S1307 protein RNA SCNV methylation COAD S38 S52 S53 S55 S56 S354 S357 S582 S610 S611 S615 S632 S661 S688 T690 S691 S706 S710 S1257 S1259 S1269 S1273 T1275 S1292 S1295 S1307 protein RNA SCNV methylation GBM S38 S52 S53 S55 S56 S354 S357 S582 S610 S611 S615 S632 S661 S688 T690 S691 S706 S710 S1257 S1259 S1269 S1273 T1275 S1292 S1295 S1307 protein RNA SCNV methylation HNSCC S38 S52 S53 S55 S56 S354 S357 S582 S610 S611 S615 S632 S661 S688 T690 S691 S706 S710 S1257 S1259 S1269 S1273 T1275 S1292 S1295 S1307 protein RNA SCNV methylation LSCC S38 S52 S53 S55 S56 S354 S357 S582 S610 S611 S615 S632 S661 S688 T690 S691 S706 S710 S1257 S1259 S1269 S1273 T1275 S1292 S1295 S1307 protein RNA SCNV methylation LUAD S38 S52 S53 S55 S56 S354 S357 S582 S610 S611 S615 S632 S661 S688 T690 S691 S706 S710 S1257 S1259 S1269 S1273 T1275 S1292 S1295 S1307 protein RNA SCNV methylation OV S38 S52 S53 S55 S56 S354 S357 S582 S610 S611 S615 S632 S661 S688 T690 S691 S706 S710 S1257 S1259 S1269 S1273 T1275 S1292 S1295 S1307 protein RNA SCNV methylation PDAC S38 S52 S53 S55 S56 S354 S357 S582 S610 S611 S615 S632 S661 S688 T690 S691 S706 S710 S1257 S1259 S1269 S1273 T1275 S1292 S1295 S1307 protein RNA SCNV methylation UCEC S38 S52 S53 S55 S56 S354 S357 S582 S610 S611 S615 S632 S661 S688 T690 S691 S706 S710 S1257 S1259 S1269 S1273 T1275 S1292 S1295 S1307 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S38
S52
S53
S55
S56
S354
S357
S582
S610
S611
S615
S632
S661
S688
T690
S691
S706
S710
S1257
S1259
S1269
S1273
T1275
S1292
S1295
S1307
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S38
S52
S53
S55
S56
S354
S357
S582
S610
S611
S615
S632
S661
S688
T690
S691
S706
S710
S1257
S1259
S1269
S1273
T1275
S1292
S1295
S1307
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.