Protein: ENSP00000295802
Gene: RETSAT

LinkedOmicsKB © 2022-2023 Zhang Lab

RETSAT:
retinol saturase

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S484ELKGKRGSDYETFKN5316----594927-53------68266811
Showing 1 to 1 of 1 rows

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S484ELKGKRGSDYETFKN-0.69---1.4e-5-----4.1e-50.35
Showing 1 to 1 of 1 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
cibersort: NeutrophilS4843.9e-9--1.5e-30.5----8e-72.8e-3
PROGENy: NFkBS4841.7e-6--0.11-0.84----3e-72.1e-3
PROGENy: TNFaS4842.5e-6--0.15-0.78----8.7e-78.3e-4
HALLMARK_CHOLESTEROL_HOMEOSTASISS4844.0e-6--0.0130.71----4.1e-34.7e-4
HALLMARK_INFLAMMATORY_RESPONSES4841.1e-5--0.180.97----4.0e-50.001
xcell: NeutrophilS4841.4e-5--0.0360.65----3.8e-50.045
HALLMARK_TNFA_SIGNALING_VIA_NFKBS4842.8e-5--0.16-0.93----2.4e-35.4e-5
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYS4843.6e-5--0.089-0.98----5.3e-31.5e-4
HALLMARK_IL6_JAK_STAT3_SIGNALINGS4848.1e-5--0.37-0.71----2.4e-51.8e-3
HALLMARK_XENOBIOTIC_METABOLISMS4849.6e-5--0.035-0.81----0.0193.4e-4
Showing 1 to 10 of 258 rows

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS484proteinRNASCNVmethylationCCRCCS484proteinRNASCNVmethylationCOADS484proteinRNASCNVmethylationGBMS484proteinRNASCNVmethylationHNSCCS484proteinRNASCNVmethylationLSCCS484proteinRNASCNVmethylationLUADS484proteinRNASCNVmethylationOVS484proteinRNASCNVmethylationPDACS484proteinRNASCNVmethylationUCECS484proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
LYNS4848.7e-10--0.0980.33----7.4e-72.7e-6
MARK2S4846.3e-8--2.8e-30.16----1.6e-40.008
FGRS4846.8e-8--0.0160.96----1.9e-86.8e-3
CSNK1G3S4842.1e-7--0.640.011----1.2e-44.6e-4
HCKS4842.7e-7--0.042-0.96----2.7e-63.0e-4
CSNK1A1S4843.9e-7--0.180.53----6.4e-53.0e-5
JAK1S4843.1e-6--0.530.05----1.3e-50.017
VRK2S4844.1e-6--0.29-----3.9e-47.6e-4
YES1S4842.0e-5--0.610.12----8.5e-41.8e-3
KITS4842.3e-5--0.160.54----4.2e-60.061
Showing 1 to 10 of 538 rows

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
TAB1S484-5.4e-6----0.69-----5.3e-6-3.5e-3
HDHD2S484-1.3e-5--0.960.23-----2.0e-6-1.9e-7
PDP1S484-1.7e-5---0.012-0.65-----0.016-1.3e-3
PPP1CBS484-3.6e-5---0.0820.28-----3.0e-4-6.3e-5
VPS29S484-3.8e-5--0.57-0.039-----0.001-5.3e-4
DUSP3S484-4.5e-5---5.6e-30.56-----9.1e-5-0.039
PNKPS484-7.7e-5---0.072-0.07-----0.057-0.017
LHPPS484-3.0e-4---0.410.38-----4.4e-7-0.026
ENOPH1S484-4.4e-4---0.250.66-----1.8e-4-9.8e-3
TNS3S484-1.2e-3---4.9e-30.11-----0.023-0.003
Showing 1 to 10 of 240 rows

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.