IFI16: interferon gamma inducible protein 16
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2oq0 chain A
2oq0 chain B
2oq0 chain C
2oq0 chain D
3b6y chain A
3b6y chain B
3rln chain A
3rlo chain A
3rnu chain A
3rnu chain B
3rnu chain C
3rnu chain D
4qgu chain A
4qgu chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S95 KVKGPALS RKRKKEV 4 105 34 - - - 15 12 9 - 23 12 - - - - - - - - - - S106 KKEVDATS PAPSTSS 10 1505 122 - 96 74 97 100 99 - 108 62 108 99 110 101 75 17 94 39 95 9 S110 DATSPAPS TSSTVKT 4 56 9 - - - - - - - - - 5 5 4 4 - - - - 25 4 T111 ATSPAPST SSTVKTE 2 23 - - - - - - - - - - - - 9 8 - - - - 6 - S113 SPAPSTSS TVKTEGA 1 9 - - - - - - 9 - - - - - - - - - - - - - T123 KTEGAEAT PGAQKRK 6 209 23 - - - - - - - 6 3 30 27 18 16 57 11 - - 18 - T149 SKVSEEQT QPPSPAG 1 10 - - - - - - - - - - 5 5 - - - - - - - - S153 EEQTQPPS PAGAGMS 10 1553 122 - 103 80 97 100 99 - 108 62 108 99 110 101 83 19 105 44 95 18 S160 SPAGAGMS TAMGRSP 4 49 17 - 12 2 - - - - 6 3 - - - - - - - - 7 2 T161 PAGAGMST AMGRSPS 6 181 33 - 20 10 4 5 - - 33 18 25 23 - - - - 7 3 - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S95 KVKGPALS RKRKKEV 0.017 - - - - 0.017 - - - - - S106 KKEVDATS PAPSTSS 2.1e-19 - 8e-20 3.2e-3 - 5.3e-4 7.9e-4 0.36 -0.77 1.5e-5 - S110 DATSPAPS TSSTVKT - - - - - - - - - - - T111 ATSPAPST SSTVKTE - - - - - - - - - - - S113 SPAPSTSS TVKTEGA - - - - - - - - - - - T123 KTEGAEAT PGAQKRK 6.3e-10 - - - - - 3.4e-9 - 4.6e-3 - - T149 SKVSEEQT QPPSPAG - - - - - - - - - - - S153 EEQTQPPS PAGAGMS 4.1e-35 - 9.3e-18 0.002 - 1.1e-11 7.9e-29 9.1e-13 -2.4e-4 2.5e-6 -4.9e-3 S160 SPAGAGMS TAMGRSP - - - - - - - - - - - T161 PAGAGMST AMGRSPS 0.24 - 0.013 - - -0.85 -0.77 - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S95
S106
S110
T111
S113
T123
T149
S153
S160
T161
S166
S168
T171
S172
S174
S180
S181
T182
S418
T420
S424
T428
T434
T435
S445
S480
T484
S536
T540
S546
T547
S549
S550
S568
S572
S575
S670
S685
S744
S776
T779
S780
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S95 S106 S110 T111 S113 T123 T149 S153 S160 T161 S166 S168 T171 S172 S174 S180 S181 T182 S418 T420 S424 T428 T434 T435 S445 S480 T484 S536 T540 S546 T547 S549 S550 S568 S572 S575 S670 S685 S744 S776 T779 S780 protein RNA SCNV methylation CCRCC S95 S106 S110 T111 S113 T123 T149 S153 S160 T161 S166 S168 T171 S172 S174 S180 S181 T182 S418 T420 S424 T428 T434 T435 S445 S480 T484 S536 T540 S546 T547 S549 S550 S568 S572 S575 S670 S685 S744 S776 T779 S780 protein RNA SCNV methylation COAD S95 S106 S110 T111 S113 T123 T149 S153 S160 T161 S166 S168 T171 S172 S174 S180 S181 T182 S418 T420 S424 T428 T434 T435 S445 S480 T484 S536 T540 S546 T547 S549 S550 S568 S572 S575 S670 S685 S744 S776 T779 S780 protein RNA SCNV methylation GBM S95 S106 S110 T111 S113 T123 T149 S153 S160 T161 S166 S168 T171 S172 S174 S180 S181 T182 S418 T420 S424 T428 T434 T435 S445 S480 T484 S536 T540 S546 T547 S549 S550 S568 S572 S575 S670 S685 S744 S776 T779 S780 protein RNA SCNV methylation HNSCC S95 S106 S110 T111 S113 T123 T149 S153 S160 T161 S166 S168 T171 S172 S174 S180 S181 T182 S418 T420 S424 T428 T434 T435 S445 S480 T484 S536 T540 S546 T547 S549 S550 S568 S572 S575 S670 S685 S744 S776 T779 S780 protein RNA SCNV methylation LSCC S95 S106 S110 T111 S113 T123 T149 S153 S160 T161 S166 S168 T171 S172 S174 S180 S181 T182 S418 T420 S424 T428 T434 T435 S445 S480 T484 S536 T540 S546 T547 S549 S550 S568 S572 S575 S670 S685 S744 S776 T779 S780 protein RNA SCNV methylation LUAD S95 S106 S110 T111 S113 T123 T149 S153 S160 T161 S166 S168 T171 S172 S174 S180 S181 T182 S418 T420 S424 T428 T434 T435 S445 S480 T484 S536 T540 S546 T547 S549 S550 S568 S572 S575 S670 S685 S744 S776 T779 S780 protein RNA SCNV methylation OV S95 S106 S110 T111 S113 T123 T149 S153 S160 T161 S166 S168 T171 S172 S174 S180 S181 T182 S418 T420 S424 T428 T434 T435 S445 S480 T484 S536 T540 S546 T547 S549 S550 S568 S572 S575 S670 S685 S744 S776 T779 S780 protein RNA SCNV methylation PDAC S95 S106 S110 T111 S113 T123 T149 S153 S160 T161 S166 S168 T171 S172 S174 S180 S181 T182 S418 T420 S424 T428 T434 T435 S445 S480 T484 S536 T540 S546 T547 S549 S550 S568 S572 S575 S670 S685 S744 S776 T779 S780 protein RNA SCNV methylation UCEC S95 S106 S110 T111 S113 T123 T149 S153 S160 T161 S166 S168 T171 S172 S174 S180 S181 T182 S418 T420 S424 T428 T434 T435 S445 S480 T484 S536 T540 S546 T547 S549 S550 S568 S572 S575 S670 S685 S744 S776 T779 S780 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S95
S106
S110
T111
S113
T123
T149
S153
S160
T161
S166
S168
T171
S172
S174
S180
S181
T182
S418
T420
S424
T428
T434
T435
S445
S480
T484
S536
T540
S546
T547
S549
S550
S568
S572
S575
S670
S685
S744
S776
T779
S780
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S95
S106
S110
T111
S113
T123
T149
S153
S160
T161
S166
S168
T171
S172
S174
S180
S181
T182
S418
T420
S424
T428
T434
T435
S445
S480
T484
S536
T540
S546
T547
S549
S550
S568
S572
S575
S670
S685
S744
S776
T779
S780
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.