APBB2: amyloid beta precursor protein binding family B member 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T34 TNRNSPAT PPNTLNL 10 919 80 - 65 54 4 5 26 - 26 17 93 84 83 76 77 17 88 37 69 18 S43 PNTLNLRS SHNELLN 1 6 - - - - - - - - - - - - - - - - 5 1 - - S44 NTLNLRSS HNELLNA 6 108 17 - 13 12 - - - - 21 14 - - 4 4 15 3 4 1 - - T62 HTETKNST PPKCRKK 2 49 - - - - 4 5 - - - - - - - - 34 6 - - - - S123 QDPNKNLS PTAVINI 9 637 9 - - - 58 50 99 - 64 38 10 9 5 4 70 16 65 27 95 18 T125 PNKNLSPT AVINITS 2 23 18 - - - - - - - - - - - - - - - 3 2 - - S160 SQPRRTKS FLNYYAD 10 732 43 - 31 31 60 48 80 - 23 15 24 22 35 32 48 12 87 38 85 18 S216 QKPNRPQS SPEDGQV 1 8 - - 8 - - - - - - - - - - - - - - - - - S217 KPNRPQSS PEDGQVA 7 401 27 - 22 19 - - 45 - - - 25 24 52 49 - - 33 13 77 15 T225 PEDGQVAT VSSSPET 2 26 9 - - - - - - - - - 9 8 - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T34 TNRNSPAT PPNTLNL -0.018 - 3.5e-7 - - 0.004 -2.2e-13 -4.3e-17 -0.34 5.8e-4 -0.32 S43 PNTLNLRS SHNELLN - - - - - - - - - - - S44 NTLNLRSS HNELLNA 9.4e-4 - - - - 9.4e-4 - - - - - T62 HTETKNST PPKCRKK - - - - - - - - - - - S123 QDPNKNLS PTAVINI -3.2e-11 - - -2.3e-5 - 0.07 - - -5.3e-3 -1.3e-6 -1.8e-6 T125 PNKNLSPT AVINITS - - - - - - - - - - - S160 SQPRRTKS FLNYYAD -0.097 - -0.93 0.17 - 0.055 -4.5e-4 -4.3e-10 -0.82 4.1e-9 -1.6e-4 S216 QKPNRPQS SPEDGQV - - - - - - - - - - - S217 KPNRPQSS PEDGQVA -1.7e-16 - -1.3e-3 - - - -1.6e-8 -1.9e-13 - 0.13 -1.8e-4 T225 PEDGQVAT VSSSPET - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T34
S43
S44
T62
S123
T125
S160
S216
S217
T225
S227
S228
S229
S300
T305
Y306
Y307
T312
S322
S330
S334
S336
S337
T339
S341
T343
S364
S380
S407
S409
S412
S561
S562
T581
S716
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T34 S43 S44 T62 S123 T125 S160 S216 S217 T225 S227 S228 S229 S300 T305 Y306 Y307 T312 S322 S330 S334 S336 S337 T339 S341 T343 S364 S380 S407 S409 S412 S561 S562 T581 S716 protein RNA SCNV methylation CCRCC T34 S43 S44 T62 S123 T125 S160 S216 S217 T225 S227 S228 S229 S300 T305 Y306 Y307 T312 S322 S330 S334 S336 S337 T339 S341 T343 S364 S380 S407 S409 S412 S561 S562 T581 S716 protein RNA SCNV methylation COAD T34 S43 S44 T62 S123 T125 S160 S216 S217 T225 S227 S228 S229 S300 T305 Y306 Y307 T312 S322 S330 S334 S336 S337 T339 S341 T343 S364 S380 S407 S409 S412 S561 S562 T581 S716 protein RNA SCNV methylation GBM T34 S43 S44 T62 S123 T125 S160 S216 S217 T225 S227 S228 S229 S300 T305 Y306 Y307 T312 S322 S330 S334 S336 S337 T339 S341 T343 S364 S380 S407 S409 S412 S561 S562 T581 S716 protein RNA SCNV methylation HNSCC T34 S43 S44 T62 S123 T125 S160 S216 S217 T225 S227 S228 S229 S300 T305 Y306 Y307 T312 S322 S330 S334 S336 S337 T339 S341 T343 S364 S380 S407 S409 S412 S561 S562 T581 S716 protein RNA SCNV methylation LSCC T34 S43 S44 T62 S123 T125 S160 S216 S217 T225 S227 S228 S229 S300 T305 Y306 Y307 T312 S322 S330 S334 S336 S337 T339 S341 T343 S364 S380 S407 S409 S412 S561 S562 T581 S716 protein RNA SCNV methylation LUAD T34 S43 S44 T62 S123 T125 S160 S216 S217 T225 S227 S228 S229 S300 T305 Y306 Y307 T312 S322 S330 S334 S336 S337 T339 S341 T343 S364 S380 S407 S409 S412 S561 S562 T581 S716 protein RNA SCNV methylation OV T34 S43 S44 T62 S123 T125 S160 S216 S217 T225 S227 S228 S229 S300 T305 Y306 Y307 T312 S322 S330 S334 S336 S337 T339 S341 T343 S364 S380 S407 S409 S412 S561 S562 T581 S716 protein RNA SCNV methylation PDAC T34 S43 S44 T62 S123 T125 S160 S216 S217 T225 S227 S228 S229 S300 T305 Y306 Y307 T312 S322 S330 S334 S336 S337 T339 S341 T343 S364 S380 S407 S409 S412 S561 S562 T581 S716 protein RNA SCNV methylation UCEC T34 S43 S44 T62 S123 T125 S160 S216 S217 T225 S227 S228 S229 S300 T305 Y306 Y307 T312 S322 S330 S334 S336 S337 T339 S341 T343 S364 S380 S407 S409 S412 S561 S562 T581 S716 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T34
S43
S44
T62
S123
T125
S160
S216
S217
T225
S227
S228
S229
S300
T305
Y306
Y307
T312
S322
S330
S334
S336
S337
T339
S341
T343
S364
S380
S407
S409
S412
S561
S562
T581
S716
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
T34
S43
S44
T62
S123
T125
S160
S216
S217
T225
S227
S228
S229
S300
T305
Y306
Y307
T312
S322
S330
S334
S336
S337
T339
S341
T343
S364
S380
S407
S409
S412
S561
S562
T581
S716
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.