DTX3L: deltex E3 ubiquitin ligase 3L
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
3pg6 chain A
3pg6 chain B
3pg6 chain C
3pg6 chain D
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
Loading, please wait
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S32 KLESYFQS SKSSGGG 2 16 - - 4 4 - - - - - - - - 4 4 - - - - - - S33 LESYFQSS KSSGGGE 1 9 - - - - - - 9 - - - - - - - - - - - - - S35 SYFQSSKS SGGGECT 3 98 - - - - - - 71 - - - 5 5 9 8 - - - - - - T89 VPIFLVPT ENSIKKN 1 8 - - 4 4 - - - - - - - - - - - - - - - - S92 FLVPTENS IKKNTRP 3 29 - - - - - - 8 - - - - - 4 4 - - - - 10 3 S202 SEQKQQFS PSMTERK 10 984 105 - 74 52 83 87 90 - 80 46 25 25 13 12 68 17 66 28 95 18 S204 QKQQFSPS MTERKPL 9 758 82 - 12 4 8 10 45 - 42 21 93 85 88 81 - - 77 33 64 13 S212 MTERKPLS QQERDSC 6 137 17 - - - - - - - 12 6 10 10 - - 21 5 24 8 18 6 S218 LSQQERDS CISPSEP 5 110 - - - - - - 35 - - - 5 4 4 4 - - 35 15 5 3 S221 QERDSCIS PSEPETK 10 1086 64 - 21 19 97 100 90 - 75 42 65 60 52 49 83 19 101 42 89 18
Tumor and normal comparison
Loading, please wait
Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S32 KLESYFQS SKSSGGG - - - - - - - - - - - S33 LESYFQSS KSSGGGE - - - - - - - - - - - S35 SYFQSSKS SGGGECT - - - - - - - - - - - T89 VPIFLVPT ENSIKKN - - - - - - - - - - - S92 FLVPTENS IKKNTRP - - - - - - - - - - - S202 SEQKQQFS PSMTERK 4e-36 - 8e-16 1.7e-20 - 2.1e-13 0.043 - 0.84 0.042 1.9e-5 S204 QKQQFSPS MTERKPL 5.2e-27 - - - - 2.3e-10 3.4e-7 8.2e-10 - 7.6e-3 1.4e-4 S212 MTERKPLS QQERDSC - - - - - - - - - - - S218 LSQQERDS CISPSEP 2.4e-6 - - - - - - - - 2.4e-6 - S221 QERDSCIS PSEPETK 3.4e-31 - 1e-9 2.9e-13 - 3.3e-8 0.007 4.2e-6 -0.097 1.1e-3 5e-7
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
Loading, please wait
all sites
S32
S33
S35
T89
S92
S202
S204
S212
S218
S221
S233
S256
S282
S284
S293
S311
S315
S351
S514
T526
S532
S535
S539
S545
S547
S548
S551
S591
T598
S602
S614
S698
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S32 S33 S35 T89 S92 S202 S204 S212 S218 S221 S233 S256 S282 S284 S293 S311 S315 S351 S514 T526 S532 S535 S539 S545 S547 S548 S551 S591 T598 S602 S614 S698 protein RNA SCNV methylation CCRCC S32 S33 S35 T89 S92 S202 S204 S212 S218 S221 S233 S256 S282 S284 S293 S311 S315 S351 S514 T526 S532 S535 S539 S545 S547 S548 S551 S591 T598 S602 S614 S698 protein RNA SCNV methylation COAD S32 S33 S35 T89 S92 S202 S204 S212 S218 S221 S233 S256 S282 S284 S293 S311 S315 S351 S514 T526 S532 S535 S539 S545 S547 S548 S551 S591 T598 S602 S614 S698 protein RNA SCNV methylation GBM S32 S33 S35 T89 S92 S202 S204 S212 S218 S221 S233 S256 S282 S284 S293 S311 S315 S351 S514 T526 S532 S535 S539 S545 S547 S548 S551 S591 T598 S602 S614 S698 protein RNA SCNV methylation HNSCC S32 S33 S35 T89 S92 S202 S204 S212 S218 S221 S233 S256 S282 S284 S293 S311 S315 S351 S514 T526 S532 S535 S539 S545 S547 S548 S551 S591 T598 S602 S614 S698 protein RNA SCNV methylation LSCC S32 S33 S35 T89 S92 S202 S204 S212 S218 S221 S233 S256 S282 S284 S293 S311 S315 S351 S514 T526 S532 S535 S539 S545 S547 S548 S551 S591 T598 S602 S614 S698 protein RNA SCNV methylation LUAD S32 S33 S35 T89 S92 S202 S204 S212 S218 S221 S233 S256 S282 S284 S293 S311 S315 S351 S514 T526 S532 S535 S539 S545 S547 S548 S551 S591 T598 S602 S614 S698 protein RNA SCNV methylation OV S32 S33 S35 T89 S92 S202 S204 S212 S218 S221 S233 S256 S282 S284 S293 S311 S315 S351 S514 T526 S532 S535 S539 S545 S547 S548 S551 S591 T598 S602 S614 S698 protein RNA SCNV methylation PDAC S32 S33 S35 T89 S92 S202 S204 S212 S218 S221 S233 S256 S282 S284 S293 S311 S315 S351 S514 T526 S532 S535 S539 S545 S547 S548 S551 S591 T598 S602 S614 S698 protein RNA SCNV methylation UCEC S32 S33 S35 T89 S92 S202 S204 S212 S218 S221 S233 S256 S282 S284 S293 S311 S315 S351 S514 T526 S532 S535 S539 S545 S547 S548 S551 S591 T598 S602 S614 S698 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S32
S33
S35
T89
S92
S202
S204
S212
S218
S221
S233
S256
S282
S284
S293
S311
S315
S351
S514
T526
S532
S535
S539
S545
S547
S548
S551
S591
T598
S602
S614
S698
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S32
S33
S35
T89
S92
S202
S204
S212
S218
S221
S233
S256
S282
S284
S293
S311
S315
S351
S514
T526
S532
S535
S539
S545
S547
S548
S551
S591
T598
S602
S614
S698
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.