METAP1: methionyl aminopeptidase 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2b3h chain A
2b3k chain A
2b3l chain A
2g6p chain A
2gz5 chain A
2nq6 chain A
2nq7 chain A
4fli chain A
4flj chain A
4flk chain A
4fll chain A
4hxx chain A
4ikr chain A
4iks chain A
4ikt chain A
4iku chain A
4iu6 chain A
4u1b chain A
4u69 chain A
4u6c chain A
4u6e chain A
4u6j chain A
4u6w chain A
4u6z chain A
4u70 chain A
4u71 chain A
4u73 chain A
4u75 chain A
4u76 chain A
5ykp chain A
5yr4 chain A
5yr5 chain A
5yr6 chain A
5yr7 chain A
6lzb chain A
6lzc chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S290 NGFSVVRS YCGHGIH 2 17 - - 4 4 - - - - - - - - 5 4 - - - - - - Y291 GFSVVRSY CGHGIHK 1 10 - - - - - - - - 7 3 - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S290 NGFSVVRS YCGHGIH - - - - - - - - - - - Y291 GFSVVRSY CGHGIHK - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S290
Y291
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S290 Y291 protein RNA SCNV methylation CCRCC S290 Y291 protein RNA SCNV methylation COAD S290 Y291 protein RNA SCNV methylation GBM S290 Y291 protein RNA SCNV methylation HNSCC S290 Y291 protein RNA SCNV methylation LSCC S290 Y291 protein RNA SCNV methylation LUAD S290 Y291 protein RNA SCNV methylation OV S290 Y291 protein RNA SCNV methylation PDAC S290 Y291 protein RNA SCNV methylation UCEC S290 Y291 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S290
Y291
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S290
Y291
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.