Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2llh chain A
2p1b chain A
2p1b chain B
2p1b chain C
2p1b chain D
2p1b chain E
2p1b chain F
2p1b chain G
2p1b chain H
2p1b chain I
2p1b chain J
2vxd chain A
5ehd chain A
5ehd chain B
5ehd chain C
5ehd chain D
5ehd chain E
5ehd chain F
5ehd chain G
5ehd chain H
5ehd chain I
5ehd chain J
5ehd chain a
5ehd chain b
5ehd chain c
5ehd chain d
5ehd chain e
5ehd chain f
5ehd chain g
5ehd chain h
5ehd chain i
5ehd chain j
7obg chain B
7obh chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S4 ____MEDS MDMDMSP 10 529 9 - 67 55 6 3 37 - 61 36 25 24 40 37 14 1 44 18 36 16 S10 DSMDMDMS PLRPQNY 5 77 13 - - - - - - - 6 4 - - 4 5 24 5 - - 5 11 S43 DENEHQLS LRTVSLG 4 74 - - 4 4 - - - - - - 5 5 - - 28 7 - - 21 - S48 QLSLRTVS LGAGAKD 6 145 - - 11 11 - - - - 5 4 5 4 5 4 - - 16 6 67 7 Y67 VEAEAMNY EGSPIKV 10 903 122 - 95 72 6 3 9 - 71 43 94 80 96 88 47 12 21 8 25 11 S70 EAMNYEGS PIKVTLA 10 1343 113 - 30 30 91 89 99 - 72 45 108 98 110 100 83 19 101 42 95 18 S82 TLATLKMS VQPTVSL 2 25 - - - - - - - - - - - - 9 9 - - - - 5 2 S88 MSVQPTVS LGGFEIT 10 1110 83 - 103 80 63 62 28 - 86 50 83 77 110 101 59 12 41 16 47 9 T95 SLGGFEIT PPVVLRL 5 141 - - - - - - - - 28 18 5 4 26 24 23 5 - - 6 2 S106 VLRLKCGS GPVHISG 6 123 9 - - - - - - - 6 3 5 4 - - 62 10 10 5 7 2
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S4 ____MEDS MDMDMSP 4.8e-8 - 3.1e-8 - - 0.88 0.24 0.7 - 8.2e-5 0.029 S10 DSMDMDMS PLRPQNY - - - - - - - - - - - S43 DENEHQLS LRTVSLG - - - - - - - - - - - S48 QLSLRTVS LGAGAKD - - - - - - - - - - - Y67 VEAEAMNY EGSPIKV 9e-22 - 1.4e-7 - - 0.2 4.6e-23 3.5e-16 -0.62 - -0.54 S70 EAMNYEGS PIKVTLA 3.1e-28 - 0.033 1.2e-5 - 0.53 6.6e-29 4.2e-19 0.95 0.26 0.006 S82 TLATLKMS VQPTVSL - - - - - - - - - - - S88 MSVQPTVS LGGFEIT -1.6e-10 - -1.4e-13 -0.49 - -2.0e-5 -0.62 -1.7e-3 -0.66 -0.6 - T95 SLGGFEIT PPVVLRL -0.1 - - - - -0.031 - -0.89 - - - S106 VLRLKCGS GPVHISG 0.13 - - - - - - - 0.13 - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S4
S10
S43
S48
Y67
S70
S82
S88
T95
S106
S112
S125
S137
S139
S143
S149
S195
T199
S207
S214
S217
S218
T219
S222
S227
T234
T237
S242
S243
S254
S260
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S4 S10 S43 S48 Y67 S70 S82 S88 T95 S106 S112 S125 S137 S139 S143 S149 S195 T199 S207 S214 S217 S218 T219 S222 S227 T234 T237 S242 S243 S254 S260 protein RNA SCNV methylation CCRCC S4 S10 S43 S48 Y67 S70 S82 S88 T95 S106 S112 S125 S137 S139 S143 S149 S195 T199 S207 S214 S217 S218 T219 S222 S227 T234 T237 S242 S243 S254 S260 protein RNA SCNV methylation COAD S4 S10 S43 S48 Y67 S70 S82 S88 T95 S106 S112 S125 S137 S139 S143 S149 S195 T199 S207 S214 S217 S218 T219 S222 S227 T234 T237 S242 S243 S254 S260 protein RNA SCNV methylation GBM S4 S10 S43 S48 Y67 S70 S82 S88 T95 S106 S112 S125 S137 S139 S143 S149 S195 T199 S207 S214 S217 S218 T219 S222 S227 T234 T237 S242 S243 S254 S260 protein RNA SCNV methylation HNSCC S4 S10 S43 S48 Y67 S70 S82 S88 T95 S106 S112 S125 S137 S139 S143 S149 S195 T199 S207 S214 S217 S218 T219 S222 S227 T234 T237 S242 S243 S254 S260 protein RNA SCNV methylation LSCC S4 S10 S43 S48 Y67 S70 S82 S88 T95 S106 S112 S125 S137 S139 S143 S149 S195 T199 S207 S214 S217 S218 T219 S222 S227 T234 T237 S242 S243 S254 S260 protein RNA SCNV methylation LUAD S4 S10 S43 S48 Y67 S70 S82 S88 T95 S106 S112 S125 S137 S139 S143 S149 S195 T199 S207 S214 S217 S218 T219 S222 S227 T234 T237 S242 S243 S254 S260 protein RNA SCNV methylation OV S4 S10 S43 S48 Y67 S70 S82 S88 T95 S106 S112 S125 S137 S139 S143 S149 S195 T199 S207 S214 S217 S218 T219 S222 S227 T234 T237 S242 S243 S254 S260 protein RNA SCNV methylation PDAC S4 S10 S43 S48 Y67 S70 S82 S88 T95 S106 S112 S125 S137 S139 S143 S149 S195 T199 S207 S214 S217 S218 T219 S222 S227 T234 T237 S242 S243 S254 S260 protein RNA SCNV methylation UCEC S4 S10 S43 S48 Y67 S70 S82 S88 T95 S106 S112 S125 S137 S139 S143 S149 S195 T199 S207 S214 S217 S218 T219 S222 S227 T234 T237 S242 S243 S254 S260 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S4
S10
S43
S48
Y67
S70
S82
S88
T95
S106
S112
S125
S137
S139
S143
S149
S195
T199
S207
S214
S217
S218
T219
S222
S227
T234
T237
S242
S243
S254
S260
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S4
S10
S43
S48
Y67
S70
S82
S88
T95
S106
S112
S125
S137
S139
S143
S149
S195
T199
S207
S214
S217
S218
T219
S222
S227
T234
T237
S242
S243
S254
S260
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.