LMTK2: lemur tyrosine kinase 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S136 KSQVARHS LNYIQEI 3 50 - - 4 4 - - - - - - 5 5 17 15 - - - - - - S393 VLQFCWLS PEKRPAA 1 9 - - - - - - 9 - - - - - - - - - - - - - S418 RLQSQRDS EVDFEQQ 7 473 - - 70 59 16 10 9 - 11 6 55 48 93 84 - - - - 12 - S439 NTNSRDSS NNAAFPI 1 9 - - - - - - - - - - - - - - - - - - 7 2 S525 GPGKQDDS GQDVPLR 1 9 - - - - - - 9 - - - - - - - - - - - - - S546 VFDAHNLS VGSDYYI 1 8 - - - - - - - - - - - - 4 4 - - - - - - S549 AHNLSVGS DYYIQLE 1 8 - - - - - - - - - - - - 4 4 - - - - - - S559 YIQLEEKS GSNLELD 1 9 - - - - - - - - - - - - - - - - - - 7 2 S561 QLEEKSGS NLELDYP 6 371 - - 58 47 - - - - 12 6 55 49 45 40 - - 7 3 42 7 S600 RSVELEES STDEDFF 2 18 - - - - - - - - 5 4 - - - - - - - - 7 2
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S136 KSQVARHS LNYIQEI - - - - - - - - - - - S393 VLQFCWLS PEKRPAA - - - - - - - - - - - S418 RLQSQRDS EVDFEQQ 1.7e-8 - -4.3e-4 - - - 1.6e-11 5.7e-11 - - - S439 NTNSRDSS NNAAFPI - - - - - - - - - - - S525 GPGKQDDS GQDVPLR - - - - - - - - - - - S546 VFDAHNLS VGSDYYI - - - - - - - - - - - S549 AHNLSVGS DYYIQLE - - - - - - - - - - - S559 YIQLEEKS GSNLELD - - - - - - - - - - - S561 QLEEKSGS NLELDYP 0.091 - 1.1e-4 - - - 0.17 -0.021 - - - S600 RSVELEES STDEDFF - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S136
S393
S418
S439
S525
S546
S549
S559
S561
S600
S601
T602
S609
S610
S617
S626
S630
S647
S735
S766
S788
T799
T802
S883
S886
S899
S901
S917
S1107
S1111
S1124
S1172
S1246
S1307
S1308
S1310
T1314
S1389
S1395
S1397
S1442
S1450
S1496
S1497
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S136 S393 S418 S439 S525 S546 S549 S559 S561 S600 S601 T602 S609 S610 S617 S626 S630 S647 S735 S766 S788 T799 T802 S883 S886 S899 S901 S917 S1107 S1111 S1124 S1172 S1246 S1307 S1308 S1310 T1314 S1389 S1395 S1397 S1442 S1450 S1496 S1497 protein RNA SCNV methylation CCRCC S136 S393 S418 S439 S525 S546 S549 S559 S561 S600 S601 T602 S609 S610 S617 S626 S630 S647 S735 S766 S788 T799 T802 S883 S886 S899 S901 S917 S1107 S1111 S1124 S1172 S1246 S1307 S1308 S1310 T1314 S1389 S1395 S1397 S1442 S1450 S1496 S1497 protein RNA SCNV methylation COAD S136 S393 S418 S439 S525 S546 S549 S559 S561 S600 S601 T602 S609 S610 S617 S626 S630 S647 S735 S766 S788 T799 T802 S883 S886 S899 S901 S917 S1107 S1111 S1124 S1172 S1246 S1307 S1308 S1310 T1314 S1389 S1395 S1397 S1442 S1450 S1496 S1497 protein RNA SCNV methylation GBM S136 S393 S418 S439 S525 S546 S549 S559 S561 S600 S601 T602 S609 S610 S617 S626 S630 S647 S735 S766 S788 T799 T802 S883 S886 S899 S901 S917 S1107 S1111 S1124 S1172 S1246 S1307 S1308 S1310 T1314 S1389 S1395 S1397 S1442 S1450 S1496 S1497 protein RNA SCNV methylation HNSCC S136 S393 S418 S439 S525 S546 S549 S559 S561 S600 S601 T602 S609 S610 S617 S626 S630 S647 S735 S766 S788 T799 T802 S883 S886 S899 S901 S917 S1107 S1111 S1124 S1172 S1246 S1307 S1308 S1310 T1314 S1389 S1395 S1397 S1442 S1450 S1496 S1497 protein RNA SCNV methylation LSCC S136 S393 S418 S439 S525 S546 S549 S559 S561 S600 S601 T602 S609 S610 S617 S626 S630 S647 S735 S766 S788 T799 T802 S883 S886 S899 S901 S917 S1107 S1111 S1124 S1172 S1246 S1307 S1308 S1310 T1314 S1389 S1395 S1397 S1442 S1450 S1496 S1497 protein RNA SCNV methylation LUAD S136 S393 S418 S439 S525 S546 S549 S559 S561 S600 S601 T602 S609 S610 S617 S626 S630 S647 S735 S766 S788 T799 T802 S883 S886 S899 S901 S917 S1107 S1111 S1124 S1172 S1246 S1307 S1308 S1310 T1314 S1389 S1395 S1397 S1442 S1450 S1496 S1497 protein RNA SCNV methylation OV S136 S393 S418 S439 S525 S546 S549 S559 S561 S600 S601 T602 S609 S610 S617 S626 S630 S647 S735 S766 S788 T799 T802 S883 S886 S899 S901 S917 S1107 S1111 S1124 S1172 S1246 S1307 S1308 S1310 T1314 S1389 S1395 S1397 S1442 S1450 S1496 S1497 protein RNA SCNV methylation PDAC S136 S393 S418 S439 S525 S546 S549 S559 S561 S600 S601 T602 S609 S610 S617 S626 S630 S647 S735 S766 S788 T799 T802 S883 S886 S899 S901 S917 S1107 S1111 S1124 S1172 S1246 S1307 S1308 S1310 T1314 S1389 S1395 S1397 S1442 S1450 S1496 S1497 protein RNA SCNV methylation UCEC S136 S393 S418 S439 S525 S546 S549 S559 S561 S600 S601 T602 S609 S610 S617 S626 S630 S647 S735 S766 S788 T799 T802 S883 S886 S899 S901 S917 S1107 S1111 S1124 S1172 S1246 S1307 S1308 S1310 T1314 S1389 S1395 S1397 S1442 S1450 S1496 S1497 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S136
S393
S418
S439
S525
S546
S549
S559
S561
S600
S601
T602
S609
S610
S617
S626
S630
S647
S735
S766
S788
T799
T802
S883
S886
S899
S901
S917
S1107
S1111
S1124
S1172
S1246
S1307
S1308
S1310
T1314
S1389
S1395
S1397
S1442
S1450
S1496
S1497
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S136
S393
S418
S439
S525
S546
S549
S559
S561
S600
S601
T602
S609
S610
S617
S626
S630
S647
S735
S766
S788
T799
T802
S883
S886
S899
S901
S917
S1107
S1111
S1124
S1172
S1246
S1307
S1308
S1310
T1314
S1389
S1395
S1397
S1442
S1450
S1496
S1497
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.