INPPL1: inositol polyphosphate phosphatase like 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2k4p chain A
2kso chain B
2mk2 chain A
3nr8 chain A
3nr8 chain B
4a9c chain A
4a9c chain B
5okm chain A
5okm chain B
5okm chain C
5okm chain D
5okm chain E
5okm chain F
5okm chain G
5okm chain H
5okn chain A
5okn chain B
5okn chain C
5okn chain D
5okn chain E
5okn chain F
5okn chain G
5okn chain H
5oko chain A
5oko chain B
5okp chain A
6squ chain A
6squ chain B
6srr chain A
6srr chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
Loading, please wait
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S132 PPDDRDAS DGEDEKP 10 967 54 - 53 33 86 93 90 - 33 18 69 64 37 31 83 19 82 34 70 18 S145 KPPLPPRS GSTSISA 5 98 18 - - - - - 54 - - - 5 5 - - 7 1 - - 5 3 S147 PLPPRSGS TSISAPT 6 113 - - 5 4 - - 52 - - - 5 4 14 12 7 1 - - - 9 T148 LPPRSGST SISAPTG 3 27 9 - - - - - 9 - - - - - 5 4 - - - - - - S149 PPRSGSTS ISAPTGP 3 28 - - - - 4 5 - - 7 3 5 4 - - - - - - - - S151 RSGSTSIS APTGPSS 1 8 - - - - - - - - - - - - - - 6 2 - - - - S157 ISAPTGPS SPLPAPE 9 400 31 - 25 24 - - 35 - 27 16 44 40 40 36 20 5 18 9 17 13 S158 SAPTGPSS PLPAPET 10 356 16 - 12 11 10 8 80 - 41 23 5 5 9 8 44 12 7 3 53 9 T165 SPLPAPET PTAPAAE 7 80 8 - 8 8 - - 9 - - - 5 5 8 8 7 1 - - 11 2 T167 LPAPETPT APAAESA 5 42 - - 8 - 3 6 9 - - - - - 5 4 7 - - - - -
Tumor and normal comparison
Loading, please wait
Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S132 PPDDRDAS DGEDEKP 0.013 - 0.56 7.3e-5 - 0.024 -0.12 -0.55 2.7e-5 -5.4e-3 0.34 S145 KPPLPPRS GSTSISA - - - - - - - - - - - S147 PLPPRSGS TSISAPT - - - - - - - - - - - T148 LPPRSGST SISAPTG - - - - - - - - - - - S149 PPRSGSTS ISAPTGP - - - - - - - - - - - S151 RSGSTSIS APTGPSS - - - - - - - - - - - S157 ISAPTGPS SPLPAPE -0.034 - 2.1e-3 - - -0.22 -9.1e-7 -0.25 - - - S158 SAPTGPSS PLPAPET -0.62 - - - - -0.43 - - 0.93 - - T165 SPLPAPET PTAPAAE - - - - - - - - - - - T167 LPAPETPT APAAESA - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
Loading, please wait
all sites
S132
S145
S147
T148
S149
S151
S157
S158
T165
T167
S173
S214
S220
S240
S241
T256
S263
S300
T306
Y886
S890
S916
T958
Y986
S1003
S1011
T1013
S1038
S1039
S1040
S1131
S1167
S1176
S1194
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S132 S145 S147 T148 S149 S151 S157 S158 T165 T167 S173 S214 S220 S240 S241 T256 S263 S300 T306 Y886 S890 S916 T958 Y986 S1003 S1011 T1013 S1038 S1039 S1040 S1131 S1167 S1176 S1194 protein RNA SCNV methylation CCRCC S132 S145 S147 T148 S149 S151 S157 S158 T165 T167 S173 S214 S220 S240 S241 T256 S263 S300 T306 Y886 S890 S916 T958 Y986 S1003 S1011 T1013 S1038 S1039 S1040 S1131 S1167 S1176 S1194 protein RNA SCNV methylation COAD S132 S145 S147 T148 S149 S151 S157 S158 T165 T167 S173 S214 S220 S240 S241 T256 S263 S300 T306 Y886 S890 S916 T958 Y986 S1003 S1011 T1013 S1038 S1039 S1040 S1131 S1167 S1176 S1194 protein RNA SCNV methylation GBM S132 S145 S147 T148 S149 S151 S157 S158 T165 T167 S173 S214 S220 S240 S241 T256 S263 S300 T306 Y886 S890 S916 T958 Y986 S1003 S1011 T1013 S1038 S1039 S1040 S1131 S1167 S1176 S1194 protein RNA SCNV methylation HNSCC S132 S145 S147 T148 S149 S151 S157 S158 T165 T167 S173 S214 S220 S240 S241 T256 S263 S300 T306 Y886 S890 S916 T958 Y986 S1003 S1011 T1013 S1038 S1039 S1040 S1131 S1167 S1176 S1194 protein RNA SCNV methylation LSCC S132 S145 S147 T148 S149 S151 S157 S158 T165 T167 S173 S214 S220 S240 S241 T256 S263 S300 T306 Y886 S890 S916 T958 Y986 S1003 S1011 T1013 S1038 S1039 S1040 S1131 S1167 S1176 S1194 protein RNA SCNV methylation LUAD S132 S145 S147 T148 S149 S151 S157 S158 T165 T167 S173 S214 S220 S240 S241 T256 S263 S300 T306 Y886 S890 S916 T958 Y986 S1003 S1011 T1013 S1038 S1039 S1040 S1131 S1167 S1176 S1194 protein RNA SCNV methylation OV S132 S145 S147 T148 S149 S151 S157 S158 T165 T167 S173 S214 S220 S240 S241 T256 S263 S300 T306 Y886 S890 S916 T958 Y986 S1003 S1011 T1013 S1038 S1039 S1040 S1131 S1167 S1176 S1194 protein RNA SCNV methylation PDAC S132 S145 S147 T148 S149 S151 S157 S158 T165 T167 S173 S214 S220 S240 S241 T256 S263 S300 T306 Y886 S890 S916 T958 Y986 S1003 S1011 T1013 S1038 S1039 S1040 S1131 S1167 S1176 S1194 protein RNA SCNV methylation UCEC S132 S145 S147 T148 S149 S151 S157 S158 T165 T167 S173 S214 S220 S240 S241 T256 S263 S300 T306 Y886 S890 S916 T958 Y986 S1003 S1011 T1013 S1038 S1039 S1040 S1131 S1167 S1176 S1194 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S132
S145
S147
T148
S149
S151
S157
S158
T165
T167
S173
S214
S220
S240
S241
T256
S263
S300
T306
Y886
S890
S916
T958
Y986
S1003
S1011
T1013
S1038
S1039
S1040
S1131
S1167
S1176
S1194
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S132
S145
S147
T148
S149
S151
S157
S158
T165
T167
S173
S214
S220
S240
S241
T256
S263
S300
T306
Y886
S890
S916
T958
Y986
S1003
S1011
T1013
S1038
S1039
S1040
S1131
S1167
S1176
S1194
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.