ARF6: ADP ribosylation factor 6
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1e0s chain A
2a5d chain A
2a5f chain A
2a5g chain A
2bao chain A
2bau chain A
2j5x chain A
2j5x chain B
2w83 chain A
2w83 chain B
2w83 chain E
3lvq chain E
3lvr chain E
3n5c chain A
3n5c chain B
3pcr chain B
4fme chain C
4fme chain F
4kax chain A
6bbp chain A
6bbq chain A
6pau chain C
6pav chain C
6pav chain D
7rk3 chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S38 YKLKLGQS VTTIPTV 7 278 6 - - - 4 5 - - 22 15 49 44 31 28 7 2 45 20 - - T40 LKLGQSVT TIPTVGF 1 9 9 - - - - - - - - - - - - - - - - - - - T41 KLGQSVTT IPTVGFN 4 102 - - - - - - - - 17 10 - - 13 12 - - 26 13 11 - T44 QSVTTIPT VGFNVET 3 43 17 - 9 8 - - - - - - - - 5 4 - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S38 YKLKLGQS VTTIPTV 0.12 - - - - -4.0e-4 2.2e-3 0.91 - 5.9e-4 - T40 LKLGQSVT TIPTVGF - - - - - - - - - - - T41 KLGQSVTT IPTVGFN 0.16 - - - - - - - - 0.16 - T44 QSVTTIPT VGFNVET - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S38
T40
T41
T44
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S38 T40 T41 T44 protein RNA SCNV methylation CCRCC S38 T40 T41 T44 protein RNA SCNV methylation COAD S38 T40 T41 T44 protein RNA SCNV methylation GBM S38 T40 T41 T44 protein RNA SCNV methylation HNSCC S38 T40 T41 T44 protein RNA SCNV methylation LSCC S38 T40 T41 T44 protein RNA SCNV methylation LUAD S38 T40 T41 T44 protein RNA SCNV methylation OV S38 T40 T41 T44 protein RNA SCNV methylation PDAC S38 T40 T41 T44 protein RNA SCNV methylation UCEC S38 T40 T41 T44 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S38
T40
T41
T44
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S38
T40
T41
T44
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.