ABRAXAS2:
abraxas 2, BRISC complex subunit

Lollipop plot

Phosphosites location and occurrence

Loading...
Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

Loading, please wait
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S79ASKVNEESLDRILKD455----45------161571--52
S159RRYNQRISLAIPNLG105438-51326319-549485978971841911
S274SRQMPSESLDPAFSP3206---------------32-9
S280ESLDPAFSPRMPSSG1066015-124202581-281858526961321070276414
S285AFSPRMPSSGFAAEG328------9---55------72
S346SSNYASTSAGLKYPG16------------------6-
S368PQRAAGDSGEDSDDS1069280-2524111688-45259380716462633914
S372AGDSGEDSDDSDYEN931932---4527-2016201543401113614332
S375SGEDSDDSDYENLID1041322-87504827-21114439141116345171911
Y377EDSDDSDYENLIDPT953751-4525352773-231329247667--185233
Showing 1 to 10 of 11 rows
rows per page

Tumor and normal comparison

Loading, please wait
Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S79ASKVNEESLDRILKD-----------
S159RRYNQRISLAIPNLG-9.1e-30-0.45----2.6e-24-1.7e-24---
S274SRQMPSESLDPAFSP-----------
S280ESLDPAFSPRMPSSG-1.3e-4---3.7e-5--0.17-1.3e-4-0.62-0.76-2.6e-42.6e-4
S285AFSPRMPSSGFAAEG-----------
S346SSNYASTSAGLKYPG-----------
S368PQRAAGDSGEDSDDS5.8e-5--6.7e-7--2.4e-31.1e-101.4e-3--0.2
S372AGDSGEDSDDSDYEN1.5e-8-----0.991.8e-32.6e-9-0.023-
S375SGEDSDDSDYENLID2.6e-5--0.44-0.562.0e-6--0.021-
Y377EDSDDSDYENLIDPT2.1e-3--5.5e-50.45-0.112.7e-47.8e-7---
Showing 1 to 10 of 11 rows
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

Loading, please wait
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS79S159S274S280S285S346S368S372S375Y377T384proteinRNASCNVmethylationCCRCCS79S159S274S280S285S346S368S372S375Y377T384proteinRNASCNVmethylationCOADS79S159S274S280S285S346S368S372S375Y377T384proteinRNASCNVmethylationGBMS79S159S274S280S285S346S368S372S375Y377T384proteinRNASCNVmethylationHNSCCS79S159S274S280S285S346S368S372S375Y377T384proteinRNASCNVmethylationLSCCS79S159S274S280S285S346S368S372S375Y377T384proteinRNASCNVmethylationLUADS79S159S274S280S285S346S368S372S375Y377T384proteinRNASCNVmethylationOVS79S159S274S280S285S346S368S372S375Y377T384proteinRNASCNVmethylationPDACS79S159S274S280S285S346S368S372S375Y377T384proteinRNASCNVmethylationUCECS79S159S274S280S285S346S368S372S375Y377T384proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

Loading, please wait
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

Loading, please wait
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.