HSP90B1: heat shock protein 90 beta family member 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S42 LGKSREGS RTDDEVV 2 34 - - - - - - 9 - - - - - - - 20 5 - - - - T44 KSREGSRT DDEVVQR 6 201 8 - 19 9 - - 37 - 21 12 - - 18 16 51 10 - - - - S64 QLDGLNAS QIRELRE 4 107 13 - - - - - - - 40 22 - - 8 8 12 4 - - - - S92 MMKLIINS LYKNKEI 2 61 - - 4 2 - - - - - - - - - - - - - - 49 6 S127 LTDENALS GNEELTV 1 9 - - - - - - 9 - - - - - - - - - - - - - S169 NLGTIAKS GTSEFLN 7 303 8 - 4 2 - - - - 47 27 39 35 21 20 - - 54 21 23 2 T171 GTIAKSGT SEFLNKM 4 31 - - 4 4 - - - - - - 5 4 5 4 - - 4 1 - - S172 TIAKSGTS EFLNKMT 10 477 24 - 7 7 19 25 46 - 6 3 49 46 67 59 7 1 31 13 49 18 T212 VADKVIVT SKHNNDT 1 9 - - - - - - 9 - - - - - - - - - - - - - S213 ADKVIVTS KHNNDTQ 1 9 - - - - - - 9 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S42 LGKSREGS RTDDEVV - - - - - - - - - - - T44 KSREGSRT DDEVVQR 0.86 - - - - -0.27 - - 0.18 - - S64 QLDGLNAS QIRELRE 0.16 - - - - 0.16 - - - - - S92 MMKLIINS LYKNKEI - - - - - - - - - - - S127 LTDENALS GNEELTV - - - - - - - - - - - S169 NLGTIAKS GTSEFLN -2.3e-4 - - - - -8.0e-4 0.91 -0.19 - -5.1e-3 - T171 GTIAKSGT SEFLNKM - - - - - - - - - - - S172 TIAKSGTS EFLNKMT -0.78 - - - - - 0.039 -0.41 - -1.6e-3 0.17 T212 VADKVIVT SKHNNDT - - - - - - - - - - - S213 ADKVIVTS KHNNDTQ - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S42
T44
S64
S92
S127
S169
T171
S172
T212
S213
T219
T286
T288
S306
S347
S385
S392
Y401
S403
S447
T450
S501
T504
S607
S650
T669
S674
T675
Y678
S680
S746
T766
T771
T774
T786
T797
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S42 T44 S64 S92 S127 S169 T171 S172 T212 S213 T219 T286 T288 S306 S347 S385 S392 Y401 S403 S447 T450 S501 T504 S607 S650 T669 S674 T675 Y678 S680 S746 T766 T771 T774 T786 T797 protein RNA SCNV methylation CCRCC S42 T44 S64 S92 S127 S169 T171 S172 T212 S213 T219 T286 T288 S306 S347 S385 S392 Y401 S403 S447 T450 S501 T504 S607 S650 T669 S674 T675 Y678 S680 S746 T766 T771 T774 T786 T797 protein RNA SCNV methylation COAD S42 T44 S64 S92 S127 S169 T171 S172 T212 S213 T219 T286 T288 S306 S347 S385 S392 Y401 S403 S447 T450 S501 T504 S607 S650 T669 S674 T675 Y678 S680 S746 T766 T771 T774 T786 T797 protein RNA SCNV methylation GBM S42 T44 S64 S92 S127 S169 T171 S172 T212 S213 T219 T286 T288 S306 S347 S385 S392 Y401 S403 S447 T450 S501 T504 S607 S650 T669 S674 T675 Y678 S680 S746 T766 T771 T774 T786 T797 protein RNA SCNV methylation HNSCC S42 T44 S64 S92 S127 S169 T171 S172 T212 S213 T219 T286 T288 S306 S347 S385 S392 Y401 S403 S447 T450 S501 T504 S607 S650 T669 S674 T675 Y678 S680 S746 T766 T771 T774 T786 T797 protein RNA SCNV methylation LSCC S42 T44 S64 S92 S127 S169 T171 S172 T212 S213 T219 T286 T288 S306 S347 S385 S392 Y401 S403 S447 T450 S501 T504 S607 S650 T669 S674 T675 Y678 S680 S746 T766 T771 T774 T786 T797 protein RNA SCNV methylation LUAD S42 T44 S64 S92 S127 S169 T171 S172 T212 S213 T219 T286 T288 S306 S347 S385 S392 Y401 S403 S447 T450 S501 T504 S607 S650 T669 S674 T675 Y678 S680 S746 T766 T771 T774 T786 T797 protein RNA SCNV methylation OV S42 T44 S64 S92 S127 S169 T171 S172 T212 S213 T219 T286 T288 S306 S347 S385 S392 Y401 S403 S447 T450 S501 T504 S607 S650 T669 S674 T675 Y678 S680 S746 T766 T771 T774 T786 T797 protein RNA SCNV methylation PDAC S42 T44 S64 S92 S127 S169 T171 S172 T212 S213 T219 T286 T288 S306 S347 S385 S392 Y401 S403 S447 T450 S501 T504 S607 S650 T669 S674 T675 Y678 S680 S746 T766 T771 T774 T786 T797 protein RNA SCNV methylation UCEC S42 T44 S64 S92 S127 S169 T171 S172 T212 S213 T219 T286 T288 S306 S347 S385 S392 Y401 S403 S447 T450 S501 T504 S607 S650 T669 S674 T675 Y678 S680 S746 T766 T771 T774 T786 T797 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S42
T44
S64
S92
S127
S169
T171
S172
T212
S213
T219
T286
T288
S306
S347
S385
S392
Y401
S403
S447
T450
S501
T504
S607
S650
T669
S674
T675
Y678
S680
S746
T766
T771
T774
T786
T797
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S42
T44
S64
S92
S127
S169
T171
S172
T212
S213
T219
T286
T288
S306
S347
S385
S392
Y401
S403
S447
T450
S501
T504
S607
S650
T669
S674
T675
Y678
S680
S746
T766
T771
T774
T786
T797
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.