STIM1: stromal interaction molecule 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2k60 chain A
2maj chain A
2maj chain C
2mak chain A
2mak chain C
3teq chain A
3teq chain B
3teq chain C
3teq chain D
4o9b chain A
4o9b chain B
4o9b chain C
4o9b chain D
6yel chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S40 GTSSGANS EESTAAE 4 73 - - - - 3 6 37 - 11 8 - - - - 7 1 - - - - S257 GLHRAEQS LHDLQER 10 1534 122 - 98 77 97 100 99 - 108 62 108 96 110 101 83 19 100 41 95 18 S340 KELESHSS WYAPEAL 6 169 - - 9 8 - - - - 37 19 25 22 17 17 7 1 5 2 - - S400 TFHVAHSS SLDDVDH 1 28 - - - - - - 28 - - - - - - - - - - - - - S401 FHVAHSSS LDDVDHK 3 54 - - - - - - 27 - 12 7 - - 4 4 - - - - - - S512 EPQHGLGS QRDLTHS 10 1519 104 - 103 80 97 100 99 - 103 59 108 97 110 100 83 19 101 43 95 18 S519 SQRDLTHS DSESSLH 8 330 8 - - - 38 34 45 - 16 10 15 14 31 29 70 14 - - 6 - S521 RDLTHSDS ESSLHMS 9 664 55 - - - 56 60 99 - 70 41 38 38 32 27 83 19 8 4 23 11 S523 LTHSDSES SLHMSDR 10 355 53 - 16 14 18 18 9 - 44 24 10 10 4 4 6 2 41 17 47 18 S524 THSDSESS LHMSDRQ 10 641 36 - 17 16 5 12 63 - 74 40 69 61 84 74 13 3 42 18 12 2
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S40 GTSSGANS EESTAAE - - - - - - - - - - - S257 GLHRAEQS LHDLQER 3.1e-17 - -3.5e-8 7.5e-18 - 2e-18 1.1e-14 5.9e-6 2.8e-3 -1.8e-4 0.59 S340 KELESHSS WYAPEAL 0.57 - - - - -0.028 2.8e-3 - - - - S400 TFHVAHSS SLDDVDH - - - - - - - - - - - S401 FHVAHSSS LDDVDHK - - - - - - - - - - - S512 EPQHGLGS QRDLTHS 7.7e-5 - -5.8e-3 -0.013 - 4.6e-5 4.1e-22 4e-15 0.28 -0.14 -8.7e-4 S519 SQRDLTHS DSESSLH 0.31 - - -0.38 - - - 2.8e-4 -0.32 - - S521 RDLTHSDS ESSLHMS 4.8e-8 - - 1.3e-3 - 3.7e-4 2.5e-3 0.004 0.049 - -0.2 S523 LTHSDSES SLHMSDR -0.012 - - - - 0.19 - - - -7.8e-5 -0.085 S524 THSDSESS LHMSDRQ 5.5e-14 - - - - 8.0e-5 1.8e-12 1.3e-15 - -7.9e-5 -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S40
S257
S340
S400
S401
S512
S519
S521
S523
S524
S528
S556
S567
S575
S595
S600
S602
S608
S613
S618
S620
S621
T626
S628
S660
T665
S667
S668
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S40 S257 S340 S400 S401 S512 S519 S521 S523 S524 S528 S556 S567 S575 S595 S600 S602 S608 S613 S618 S620 S621 T626 S628 S660 T665 S667 S668 protein RNA SCNV methylation CCRCC S40 S257 S340 S400 S401 S512 S519 S521 S523 S524 S528 S556 S567 S575 S595 S600 S602 S608 S613 S618 S620 S621 T626 S628 S660 T665 S667 S668 protein RNA SCNV methylation COAD S40 S257 S340 S400 S401 S512 S519 S521 S523 S524 S528 S556 S567 S575 S595 S600 S602 S608 S613 S618 S620 S621 T626 S628 S660 T665 S667 S668 protein RNA SCNV methylation GBM S40 S257 S340 S400 S401 S512 S519 S521 S523 S524 S528 S556 S567 S575 S595 S600 S602 S608 S613 S618 S620 S621 T626 S628 S660 T665 S667 S668 protein RNA SCNV methylation HNSCC S40 S257 S340 S400 S401 S512 S519 S521 S523 S524 S528 S556 S567 S575 S595 S600 S602 S608 S613 S618 S620 S621 T626 S628 S660 T665 S667 S668 protein RNA SCNV methylation LSCC S40 S257 S340 S400 S401 S512 S519 S521 S523 S524 S528 S556 S567 S575 S595 S600 S602 S608 S613 S618 S620 S621 T626 S628 S660 T665 S667 S668 protein RNA SCNV methylation LUAD S40 S257 S340 S400 S401 S512 S519 S521 S523 S524 S528 S556 S567 S575 S595 S600 S602 S608 S613 S618 S620 S621 T626 S628 S660 T665 S667 S668 protein RNA SCNV methylation OV S40 S257 S340 S400 S401 S512 S519 S521 S523 S524 S528 S556 S567 S575 S595 S600 S602 S608 S613 S618 S620 S621 T626 S628 S660 T665 S667 S668 protein RNA SCNV methylation PDAC S40 S257 S340 S400 S401 S512 S519 S521 S523 S524 S528 S556 S567 S575 S595 S600 S602 S608 S613 S618 S620 S621 T626 S628 S660 T665 S667 S668 protein RNA SCNV methylation UCEC S40 S257 S340 S400 S401 S512 S519 S521 S523 S524 S528 S556 S567 S575 S595 S600 S602 S608 S613 S618 S620 S621 T626 S628 S660 T665 S667 S668 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S40
S257
S340
S400
S401
S512
S519
S521
S523
S524
S528
S556
S567
S575
S595
S600
S602
S608
S613
S618
S620
S621
T626
S628
S660
T665
S667
S668
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S40
S257
S340
S400
S401
S512
S519
S521
S523
S524
S528
S556
S567
S575
S595
S600
S602
S608
S613
S618
S620
S621
T626
S628
S660
T665
S667
S668
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.