RRM1: ribonucleotide reductase catalytic subunit M1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2wgh chain A
2wgh chain B
3hnc chain A
3hnc chain B
3hnd chain A
3hnd chain B
3hne chain A
3hne chain B
3hnf chain A
3hnf chain B
4x3v chain A
4x3v chain B
5d1y chain A
5d1y chain B
5tus chain A
5tus chain B
6aui chain A
6aui chain B
6aui chain C
6aui chain D
6aui chain E
6aui chain F
6l3r chain A
6l3r chain E
6l7l chain A
6l7l chain E
6lkm chain A
6lkm chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S119 HSPMVAKS TLDIVLA 2 18 9 - - - - - 9 - - - - - - - - - - - - - S631 IYTRRVLS GEFQIVN 1 10 - - - - - - - - - - 5 5 - - - - - - - - S780 NTAAMVCS LENRDEC 1 7 - - - - - - - - - - - - - - - - - - 5 2
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S119 HSPMVAKS TLDIVLA - - - - - - - - - - - S631 IYTRRVLS GEFQIVN - - - - - - - - - - - S780 NTAAMVCS LENRDEC - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S119
S631
S780
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S119 S631 S780 protein RNA SCNV methylation CCRCC S119 S631 S780 protein RNA SCNV methylation COAD S119 S631 S780 protein RNA SCNV methylation GBM S119 S631 S780 protein RNA SCNV methylation HNSCC S119 S631 S780 protein RNA SCNV methylation LSCC S119 S631 S780 protein RNA SCNV methylation LUAD S119 S631 S780 protein RNA SCNV methylation OV S119 S631 S780 protein RNA SCNV methylation PDAC S119 S631 S780 protein RNA SCNV methylation UCEC S119 S631 S780 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S119
S631
S780
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S119
S631
S780
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.