DDB1: damage specific DNA binding protein 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2b5l chain A
2b5l chain B
2b5m chain A
2b5n chain A
2b5n chain B
2b5n chain C
2b5n chain D
2hye chain A
3e0c chain A
3ei1 chain A
3ei2 chain A
3ei3 chain A
3ei4 chain A
3ei4 chain C
3ei4 chain E
3i7h chain A
3i7k chain A
3i7l chain A
3i7n chain A
3i7o chain A
3i7p chain A
3i89 chain A
3i8c chain A
3i8e chain A
3i8e chain B
4a08 chain A
4a09 chain A
4a0a chain A
4a0b chain A
4a0b chain C
4a0k chain C
4a0l chain A
4a0l chain C
4a11 chain A
4ci1 chain A
4ci2 chain A
4ci3 chain A
4e54 chain A
4e5z chain A
4tz4 chain A
5fqd chain A
5fqd chain D
5hxb chain B
5hxb chain Y
5jk7 chain A
5jk7 chain B
5v3o chain A
6bn7 chain A
6bn8 chain A
6bn9 chain A
6bnb chain A
6boy chain A
6dsz chain A
6dsz chain B
6fcv chain A
6h0f chain A
6h0f chain D
6h0f chain G
6h0f chain J
6h0g chain A
6h0g chain D
6pai chain A
6q0r chain A
6q0v chain A
6q0w chain A
6r8y chain K
6r8z chain K
6r90 chain K
6r91 chain K
6r92 chain K
6sj7 chain B
6td3 chain A
6td3 chain D
6td3 chain G
6ud7 chain B
6ue5 chain B
6uml chain A
6xk9 chain B
6xk9 chain Y
6zue chain A
6zx9 chain A
7lps chain A
7lps chain D
7lps chain G
7lps chain J
7okq chain A
7okq chain E
7okq chain I
7okq chain M
7oo3 chain d
7oob chain d
7oop chain d
7opc chain d
7opd chain d
7ukn chain A
8cvp chain A
8d7u chain A
8d7v chain A
8d7w chain A
8d7x chain A
8d7y chain A
8d7z chain A
8d80 chain A
8d81 chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S116 QDRIGRPS ETGIIGI 1 9 - - - - - - - - - - - - - - - - - - 7 2 S645 LRTFRSLS TTNVFAC 2 53 - - - - - - 45 - - - - - - - 7 1 - - - - S720 RTVPLYES PRKICYQ 1 7 - - - - - - - - 5 2 - - - - - - - - - - S757 TALRPSAS TQALSSS 1 15 - - - - - - - - - - - - - - - - - - 10 5 T758 ALRPSAST QALSSSV 1 19 - - - - - - - - - - - - - - - - - - 10 9 S766 QALSSSVS SSKLFSS 7 330 31 - 13 12 - - 55 - - - 45 42 13 12 - - 45 21 41 - T1125 SGMKREAT ADDLIKV 5 121 7 - - - 5 4 18 - - - 9 8 - - - - - - 52 18
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S116 QDRIGRPS ETGIIGI - - - - - - - - - - - S645 LRTFRSLS TTNVFAC - - - - - - - - - - - S720 RTVPLYES PRKICYQ - - - - - - - - - - - S757 TALRPSAS TQALSSS - - - - - - - - - - - T758 ALRPSAST QALSSSV - - - - - - - - - - - S766 QALSSSVS SSKLFSS -0.91 - - - - - 1e-7 - - -4.3e-8 - T1125 SGMKREAT ADDLIKV 0.21 - - - - - - - - - 0.21
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S116
S645
S720
S757
T758
S766
T1125
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S116 S645 S720 S757 T758 S766 T1125 protein RNA SCNV methylation CCRCC S116 S645 S720 S757 T758 S766 T1125 protein RNA SCNV methylation COAD S116 S645 S720 S757 T758 S766 T1125 protein RNA SCNV methylation GBM S116 S645 S720 S757 T758 S766 T1125 protein RNA SCNV methylation HNSCC S116 S645 S720 S757 T758 S766 T1125 protein RNA SCNV methylation LSCC S116 S645 S720 S757 T758 S766 T1125 protein RNA SCNV methylation LUAD S116 S645 S720 S757 T758 S766 T1125 protein RNA SCNV methylation OV S116 S645 S720 S757 T758 S766 T1125 protein RNA SCNV methylation PDAC S116 S645 S720 S757 T758 S766 T1125 protein RNA SCNV methylation UCEC S116 S645 S720 S757 T758 S766 T1125 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S116
S645
S720
S757
T758
S766
T1125
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S116
S645
S720
S757
T758
S766
T1125
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.