FADD: Fas associated via death domain
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1a1w chain A
1a1z chain A
1e3y chain A
1e41 chain A
2gf5 chain A
3ezq chain B
3ezq chain D
3ezq chain F
3ezq chain H
3ezq chain J
3ezq chain L
3ezq chain N
3ezq chain P
3oq9 chain H
3oq9 chain I
3oq9 chain J
3oq9 chain K
3oq9 chain L
6aci chain H
7lxc chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S41 RKLERVQS GLDLFSM 9 990 61 - 102 80 65 61 62 - 108 62 84 72 110 99 - - 4 1 19 - S122 LARQLKVS DTKIDSI 1 9 9 - - - - - - - - - - - - - - - - - - - S194 QNRSGAMS PMSWNSD 7 431 18 - - - 57 59 81 - - - 30 26 12 13 - - 16 6 95 18
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S41 RKLERVQS GLDLFSM 3.9e-4 - -0.31 0.19 - 0.27 0.032 1.1e-5 - - - S122 LARQLKVS DTKIDSI - - - - - - - - - - - S194 QNRSGAMS PMSWNSD -1.3e-7 - - -6.4e-5 - - -1.3e-3 - - - -0.052
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S41
S122
S194
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S41 S122 S194 protein RNA SCNV methylation CCRCC S41 S122 S194 protein RNA SCNV methylation COAD S41 S122 S194 protein RNA SCNV methylation GBM S41 S122 S194 protein RNA SCNV methylation HNSCC S41 S122 S194 protein RNA SCNV methylation LSCC S41 S122 S194 protein RNA SCNV methylation LUAD S41 S122 S194 protein RNA SCNV methylation OV S41 S122 S194 protein RNA SCNV methylation PDAC S41 S122 S194 protein RNA SCNV methylation UCEC S41 S122 S194 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S41
S122
S194
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S41
S122
S194
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.