Protein: ENSP00000302886
Gene: PA2G4

LinkedOmicsKB © 2022-2023 Zhang Lab

PA2G4:
proliferation-associated 2G4

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S2______MSGEDEQQE61596-----17---191798328--394
T180VAHSFNCTPIEGMLS110--------73----------
S335NGPMRITSGPFEPDL469----------55121271--27-
S360ELKALLQSSASRKTQ17----------------52--
S361LKALLQSSASRKTQK968197---243081-221483753936481136135913
S363ALLQSSASRKTQKKK1039118-1212459-4124353127241434817616
T377KKKKASKTAENATSG110----------55--------
S383KTAENATSGETLEEN81888---11772-531089961--336
T386ENATSGETLEENEAG1098962-7552666863-87467970806830732147218
Showing 1 to 9 of 9 rows

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S2______MSGEDEQQE-----------
T180VAHSFNCTPIEGMLS-----------
S335NGPMRITSGPFEPDL-----------
S360ELKALLQSSASRKTQ-----------
S361LKALLQSSASRKTQK7.1e-28--0.011-1.3e-45.3e-201.6e-80.0330.0295.2e-4
S363ALLQSSASRKTQKKK-1.5e-4----0.067-3.3e-8-0.11--0.022-
T377KKKKASKTAENATSG-----------
S383KTAENATSGETLEEN-----------
T386ENATSGETLEENEAG3.1e-14-0.0034.9e-3-1.7e-52.8e-103.3e-8--4.9e-30.32
Showing 1 to 9 of 9 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS2T180S335S360S361S363T377S383T386proteinRNASCNVmethylationCCRCCS2T180S335S360S361S363T377S383T386proteinRNASCNVmethylationCOADS2T180S335S360S361S363T377S383T386proteinRNASCNVmethylationGBMS2T180S335S360S361S363T377S383T386proteinRNASCNVmethylationHNSCCS2T180S335S360S361S363T377S383T386proteinRNASCNVmethylationLSCCS2T180S335S360S361S363T377S383T386proteinRNASCNVmethylationLUADS2T180S335S360S361S363T377S383T386proteinRNASCNVmethylationOVS2T180S335S360S361S363T377S383T386proteinRNASCNVmethylationPDACS2T180S335S360S361S363T377S383T386proteinRNASCNVmethylationUCECS2T180S335S360S361S363T377S383T386proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.