AFAP1L2: actin filament associated protein 1 like 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S28 LDQENLSS TALVKKS 1 14 - - - - - - - - - - - - - - - - - - 11 3 S48 LRLYTKSS SSDEEYI 1 8 - - - - - - - - - - - - - - - - - - 6 2 S49 RLYTKSSS SDEEYIY 1 6 - - - - - - - - - - - - - - - - - - 6 - S50 LYTKSSSS DEEYIYM 5 121 - - 4 4 - - 8 - 5 3 14 13 - - - - - - 56 14 Y54 SSSSDEEY IYMNKVT 2 68 - - - - - - 18 - - - - - - - - - - - 41 9 Y56 SSDEEYIY MNKVTIN 1 28 - - - - - - - - - - - - - - - - - - 17 11 S96 HSSAPQKS LPDLPPP 1 23 - - - - - - - - - - - - - - - - - - 12 11 S119 LAIPKTES PEGYYEE 2 22 - - - - - - - - - - 5 4 - - - - - - 13 - Y130 YYEEAEPY DTSLNED 5 74 14 - 4 4 - - - - 18 10 9 9 - - - - - - 6 - T132 EEAEPYDT SLNEDGE 1 8 - - - - - - - - - - - - - - - - - - 5 3
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S28 LDQENLSS TALVKKS - - - - - - - - - - - S48 LRLYTKSS SSDEEYI - - - - - - - - - - - S49 RLYTKSSS SDEEYIY - - - - - - - - - - - S50 LYTKSSSS DEEYIYM -0.012 - - - - - - - - - -0.012 Y54 SSSSDEEY IYMNKVT - - - - - - - - - - - Y56 SSDEEYIY MNKVTIN - - - - - - - - - - - S96 HSSAPQKS LPDLPPP - - - - - - - - - - - S119 LAIPKTES PEGYYEE - - - - - - - - - - - Y130 YYEEAEPY DTSLNED - - - - - - - - - - - T132 EEAEPYDT SLNEDGE - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S28
S48
S49
S50
Y54
Y56
S96
S119
Y130
T132
S133
S147
S165
S274
S278
T284
S310
S328
S334
S344
T345
S346
S358
Y359
S374
Y383
S408
Y413
S414
S475
S484
T541
S559
T561
S563
T569
S600
S627
T635
S640
S651
T761
S767
T774
T782
S796
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S28 S48 S49 S50 Y54 Y56 S96 S119 Y130 T132 S133 S147 S165 S274 S278 T284 S310 S328 S334 S344 T345 S346 S358 Y359 S374 Y383 S408 Y413 S414 S475 S484 T541 S559 T561 S563 T569 S600 S627 T635 S640 S651 T761 S767 T774 T782 S796 protein RNA SCNV methylation CCRCC S28 S48 S49 S50 Y54 Y56 S96 S119 Y130 T132 S133 S147 S165 S274 S278 T284 S310 S328 S334 S344 T345 S346 S358 Y359 S374 Y383 S408 Y413 S414 S475 S484 T541 S559 T561 S563 T569 S600 S627 T635 S640 S651 T761 S767 T774 T782 S796 protein RNA SCNV methylation COAD S28 S48 S49 S50 Y54 Y56 S96 S119 Y130 T132 S133 S147 S165 S274 S278 T284 S310 S328 S334 S344 T345 S346 S358 Y359 S374 Y383 S408 Y413 S414 S475 S484 T541 S559 T561 S563 T569 S600 S627 T635 S640 S651 T761 S767 T774 T782 S796 protein RNA SCNV methylation GBM S28 S48 S49 S50 Y54 Y56 S96 S119 Y130 T132 S133 S147 S165 S274 S278 T284 S310 S328 S334 S344 T345 S346 S358 Y359 S374 Y383 S408 Y413 S414 S475 S484 T541 S559 T561 S563 T569 S600 S627 T635 S640 S651 T761 S767 T774 T782 S796 protein RNA SCNV methylation HNSCC S28 S48 S49 S50 Y54 Y56 S96 S119 Y130 T132 S133 S147 S165 S274 S278 T284 S310 S328 S334 S344 T345 S346 S358 Y359 S374 Y383 S408 Y413 S414 S475 S484 T541 S559 T561 S563 T569 S600 S627 T635 S640 S651 T761 S767 T774 T782 S796 protein RNA SCNV methylation LSCC S28 S48 S49 S50 Y54 Y56 S96 S119 Y130 T132 S133 S147 S165 S274 S278 T284 S310 S328 S334 S344 T345 S346 S358 Y359 S374 Y383 S408 Y413 S414 S475 S484 T541 S559 T561 S563 T569 S600 S627 T635 S640 S651 T761 S767 T774 T782 S796 protein RNA SCNV methylation LUAD S28 S48 S49 S50 Y54 Y56 S96 S119 Y130 T132 S133 S147 S165 S274 S278 T284 S310 S328 S334 S344 T345 S346 S358 Y359 S374 Y383 S408 Y413 S414 S475 S484 T541 S559 T561 S563 T569 S600 S627 T635 S640 S651 T761 S767 T774 T782 S796 protein RNA SCNV methylation OV S28 S48 S49 S50 Y54 Y56 S96 S119 Y130 T132 S133 S147 S165 S274 S278 T284 S310 S328 S334 S344 T345 S346 S358 Y359 S374 Y383 S408 Y413 S414 S475 S484 T541 S559 T561 S563 T569 S600 S627 T635 S640 S651 T761 S767 T774 T782 S796 protein RNA SCNV methylation PDAC S28 S48 S49 S50 Y54 Y56 S96 S119 Y130 T132 S133 S147 S165 S274 S278 T284 S310 S328 S334 S344 T345 S346 S358 Y359 S374 Y383 S408 Y413 S414 S475 S484 T541 S559 T561 S563 T569 S600 S627 T635 S640 S651 T761 S767 T774 T782 S796 protein RNA SCNV methylation UCEC S28 S48 S49 S50 Y54 Y56 S96 S119 Y130 T132 S133 S147 S165 S274 S278 T284 S310 S328 S334 S344 T345 S346 S358 Y359 S374 Y383 S408 Y413 S414 S475 S484 T541 S559 T561 S563 T569 S600 S627 T635 S640 S651 T761 S767 T774 T782 S796 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S28
S48
S49
S50
Y54
Y56
S96
S119
Y130
T132
S133
S147
S165
S274
S278
T284
S310
S328
S334
S344
T345
S346
S358
Y359
S374
Y383
S408
Y413
S414
S475
S484
T541
S559
T561
S563
T569
S600
S627
T635
S640
S651
T761
S767
T774
T782
S796
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S28
S48
S49
S50
Y54
Y56
S96
S119
Y130
T132
S133
S147
S165
S274
S278
T284
S310
S328
S334
S344
T345
S346
S358
Y359
S374
Y383
S408
Y413
S414
S475
S484
T541
S559
T561
S563
T569
S600
S627
T635
S640
S651
T761
S767
T774
T782
S796
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.