LUZP1: leucine zipper protein 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S57 KVIQAEGS NSSMLAE 10 919 41 - 45 42 50 48 61 - 65 37 88 81 84 77 46 11 65 29 33 16 S59 IQAEGSNS SMLAEIE 6 84 6 - 14 12 - - - - 6 4 10 9 8 9 - - - - 6 - S60 QAEGSNSS MLAEIEV 2 39 - - 11 11 - - - - - - - - 8 9 - - - - - - S233 RDYTRNAS NLERNDL 10 872 34 - 83 60 27 27 18 - 103 58 73 66 59 51 68 16 84 36 - 9 S381 TKFRGHGS EASVSKH 2 62 - - - - - - - - - - 10 8 - - - - 33 11 - - S384 RGHGSEAS VSKHTAR 3 39 6 - - - - - 9 - - - - - - - 20 4 - - - - S394 KHTARELS PQHKRER 10 1246 113 - 48 36 97 100 99 - 90 54 64 58 72 63 83 19 97 40 95 18 S422 SLSNRQVS SPSFTNR 4 91 - - - - - - 36 - 10 7 - - - - 7 1 - - 18 12 S423 LSNRQVSS PSFTNRR 10 1165 100 - 49 32 35 28 72 - 103 59 104 95 106 95 57 11 76 30 95 18 S425 NRQVSSPS FTNRRAA 4 109 - - - - - - - - 25 13 - - 18 16 - - 6 2 29 -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S57 KVIQAEGS NSSMLAE -1.3e-11 - 0.3 -3.7e-6 - -0.68 -4.3e-15 -2.3e-17 -0.24 0.18 0.3 S59 IQAEGSNS SMLAEIE - - - - - - - - - - - S60 QAEGSNSS MLAEIEV - - - - - - - - - - - S233 RDYTRNAS NLERNDL 3.6e-7 - 0.012 -0.64 - 5.6e-9 -5.3e-3 1.9e-6 0.91 4.3e-4 - S381 TKFRGHGS EASVSKH 2.4e-4 - - - - - - - - 2.4e-4 - S384 RGHGSEAS VSKHTAR - - - - - - - - - - - S394 KHTARELS PQHKRER 2.5e-15 - -0.13 8.3e-9 - 4.6e-11 6.2e-5 0.32 4.6e-6 1.7e-10 -1.0e-5 S422 SLSNRQVS SPSFTNR - - - - - - - - - - - S423 LSNRQVSS PSFTNRR 7.3e-44 - 2.6e-5 0.038 - 2.9e-17 1.2e-13 4.6e-13 0.067 2.4e-6 8.2e-4 S425 NRQVSSPS FTNRRAA 2.1e-3 - - - - 2.1e-3 - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S57
S59
S60
S233
S381
S384
S394
S422
S423
S425
T427
S440
T441
S443
T510
S512
S531
S569
S570
S573
S574
S575
Y607
S611
S638
S659
T679
S690
S703
S745
S772
S794
S795
S801
S803
S804
S805
S820
S878
S905
S932
S957
T958
S982
T993
S995
S996
S1021
S1023
S1042
S1046
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S57 S59 S60 S233 S381 S384 S394 S422 S423 S425 T427 S440 T441 S443 T510 S512 S531 S569 S570 S573 S574 S575 Y607 S611 S638 S659 T679 S690 S703 S745 S772 S794 S795 S801 S803 S804 S805 S820 S878 S905 S932 S957 T958 S982 T993 S995 S996 S1021 S1023 S1042 S1046 protein RNA SCNV methylation CCRCC S57 S59 S60 S233 S381 S384 S394 S422 S423 S425 T427 S440 T441 S443 T510 S512 S531 S569 S570 S573 S574 S575 Y607 S611 S638 S659 T679 S690 S703 S745 S772 S794 S795 S801 S803 S804 S805 S820 S878 S905 S932 S957 T958 S982 T993 S995 S996 S1021 S1023 S1042 S1046 protein RNA SCNV methylation COAD S57 S59 S60 S233 S381 S384 S394 S422 S423 S425 T427 S440 T441 S443 T510 S512 S531 S569 S570 S573 S574 S575 Y607 S611 S638 S659 T679 S690 S703 S745 S772 S794 S795 S801 S803 S804 S805 S820 S878 S905 S932 S957 T958 S982 T993 S995 S996 S1021 S1023 S1042 S1046 protein RNA SCNV methylation GBM S57 S59 S60 S233 S381 S384 S394 S422 S423 S425 T427 S440 T441 S443 T510 S512 S531 S569 S570 S573 S574 S575 Y607 S611 S638 S659 T679 S690 S703 S745 S772 S794 S795 S801 S803 S804 S805 S820 S878 S905 S932 S957 T958 S982 T993 S995 S996 S1021 S1023 S1042 S1046 protein RNA SCNV methylation HNSCC S57 S59 S60 S233 S381 S384 S394 S422 S423 S425 T427 S440 T441 S443 T510 S512 S531 S569 S570 S573 S574 S575 Y607 S611 S638 S659 T679 S690 S703 S745 S772 S794 S795 S801 S803 S804 S805 S820 S878 S905 S932 S957 T958 S982 T993 S995 S996 S1021 S1023 S1042 S1046 protein RNA SCNV methylation LSCC S57 S59 S60 S233 S381 S384 S394 S422 S423 S425 T427 S440 T441 S443 T510 S512 S531 S569 S570 S573 S574 S575 Y607 S611 S638 S659 T679 S690 S703 S745 S772 S794 S795 S801 S803 S804 S805 S820 S878 S905 S932 S957 T958 S982 T993 S995 S996 S1021 S1023 S1042 S1046 protein RNA SCNV methylation LUAD S57 S59 S60 S233 S381 S384 S394 S422 S423 S425 T427 S440 T441 S443 T510 S512 S531 S569 S570 S573 S574 S575 Y607 S611 S638 S659 T679 S690 S703 S745 S772 S794 S795 S801 S803 S804 S805 S820 S878 S905 S932 S957 T958 S982 T993 S995 S996 S1021 S1023 S1042 S1046 protein RNA SCNV methylation OV S57 S59 S60 S233 S381 S384 S394 S422 S423 S425 T427 S440 T441 S443 T510 S512 S531 S569 S570 S573 S574 S575 Y607 S611 S638 S659 T679 S690 S703 S745 S772 S794 S795 S801 S803 S804 S805 S820 S878 S905 S932 S957 T958 S982 T993 S995 S996 S1021 S1023 S1042 S1046 protein RNA SCNV methylation PDAC S57 S59 S60 S233 S381 S384 S394 S422 S423 S425 T427 S440 T441 S443 T510 S512 S531 S569 S570 S573 S574 S575 Y607 S611 S638 S659 T679 S690 S703 S745 S772 S794 S795 S801 S803 S804 S805 S820 S878 S905 S932 S957 T958 S982 T993 S995 S996 S1021 S1023 S1042 S1046 protein RNA SCNV methylation UCEC S57 S59 S60 S233 S381 S384 S394 S422 S423 S425 T427 S440 T441 S443 T510 S512 S531 S569 S570 S573 S574 S575 Y607 S611 S638 S659 T679 S690 S703 S745 S772 S794 S795 S801 S803 S804 S805 S820 S878 S905 S932 S957 T958 S982 T993 S995 S996 S1021 S1023 S1042 S1046 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S57
S59
S60
S233
S381
S384
S394
S422
S423
S425
T427
S440
T441
S443
T510
S512
S531
S569
S570
S573
S574
S575
Y607
S611
S638
S659
T679
S690
S703
S745
S772
S794
S795
S801
S803
S804
S805
S820
S878
S905
S932
S957
T958
S982
T993
S995
S996
S1021
S1023
S1042
S1046
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S57
S59
S60
S233
S381
S384
S394
S422
S423
S425
T427
S440
T441
S443
T510
S512
S531
S569
S570
S573
S574
S575
Y607
S611
S638
S659
T679
S690
S703
S745
S772
S794
S795
S801
S803
S804
S805
S820
S878
S905
S932
S957
T958
S982
T993
S995
S996
S1021
S1023
S1042
S1046
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.