PRPF8: pre-mRNA processing factor 8
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
3e9l chain A
3enb chain A
3enb chain B
3jcr chain A
3lru chain A
3lru chain B
4jk7 chain A
4jk7 chain B
4jk8 chain A
4jk8 chain B
4jk9 chain A
4jk9 chain B
4jka chain A
4jka chain B
4jkb chain A
4jkb chain B
4jkc chain A
4jkc chain B
4jkd chain A
4jkd chain B
4jke chain A
4jke chain B
4jkf chain A
4jkf chain B
4jkg chain A
4jkg chain B
4jkh chain A
4jkh chain B
4kit chain C
5mqf chain A
5o9z chain A
5xjc chain A
5yzg chain A
5z56 chain A
5z57 chain A
5z58 chain A
6ah0 chain A
6ahd chain A
6ff4 chain A
6ff7 chain A
6icz chain A
6id0 chain A
6id1 chain A
6qdv chain A
6qw6 chain 5A
6qx9 chain 5A
6s8q chain J
6s9i chain J
6zym chain A
7a5p chain A
7aav chain A
7abf chain A
7abg chain A
7abi chain A
7bdi chain J
7bdj chain J
7bdk chain J
7bdl chain J
7dvq chain A
7os2 chain J
7px3 chain J
7w59 chain A
7w5a chain A
7w5b chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
Loading, please wait
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S1358 THFRSGMS HEEDQLI 6 84 13 - - - - - 9 - 10 7 5 5 - - 7 1 - - 22 5 T1404 IAQNRRLT LEDLEDS 3 33 - - 4 4 - - - - - - 10 9 - - - - - - 6 - S1512 KASGFEES MKWKKLT 2 158 - - - - - - - - 64 36 30 28 - - - - - - - - T2042 EQSQLTAT QTRTVNK 1 18 - - - - 10 8 - - - - - - - - - - - - - - S2060 EIITSTTS NYETQTF 3 45 - - - - - - 9 - - - - - 5 4 - - - - 22 5 S2079 EWRVRAIS AANLHLR 3 34 13 - - - - - - - - - - - - - 7 1 - - 11 2 S2093 RTNHIYVS SDDIKET 2 17 - - - - - - 9 - - - - - - - - - - - 6 2
Tumor and normal comparison
Loading, please wait
Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S1358 THFRSGMS HEEDQLI - - - - - - - - - - - T1404 IAQNRRLT LEDLEDS - - - - - - - - - - - S1512 KASGFEES MKWKKLT 2.6e-8 - - - - 3.2e-7 5.7e-3 - - - - T2042 EQSQLTAT QTRTVNK - - - - - - - - - - - S2060 EIITSTTS NYETQTF - - - - - - - - - - - S2079 EWRVRAIS AANLHLR - - - - - - - - - - - S2093 RTNHIYVS SDDIKET - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
Loading, please wait
all sites
S1358
T1404
S1512
T2042
S2060
S2079
S2093
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S1358 T1404 S1512 T2042 S2060 S2079 S2093 protein RNA SCNV methylation CCRCC S1358 T1404 S1512 T2042 S2060 S2079 S2093 protein RNA SCNV methylation COAD S1358 T1404 S1512 T2042 S2060 S2079 S2093 protein RNA SCNV methylation GBM S1358 T1404 S1512 T2042 S2060 S2079 S2093 protein RNA SCNV methylation HNSCC S1358 T1404 S1512 T2042 S2060 S2079 S2093 protein RNA SCNV methylation LSCC S1358 T1404 S1512 T2042 S2060 S2079 S2093 protein RNA SCNV methylation LUAD S1358 T1404 S1512 T2042 S2060 S2079 S2093 protein RNA SCNV methylation OV S1358 T1404 S1512 T2042 S2060 S2079 S2093 protein RNA SCNV methylation PDAC S1358 T1404 S1512 T2042 S2060 S2079 S2093 protein RNA SCNV methylation UCEC S1358 T1404 S1512 T2042 S2060 S2079 S2093 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S1358
T1404
S1512
T2042
S2060
S2079
S2093
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S1358
T1404
S1512
T2042
S2060
S2079
S2093
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.