Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1xkt chain A
1xkt chain B
2cg5 chain B
2jfd chain A
2jfd chain B
2jfd chain C
2jfd chain D
2jfk chain A
2jfk chain B
2jfk chain C
2jfk chain D
2px6 chain A
2px6 chain B
3hhd chain A
3hhd chain B
3hhd chain C
3hhd chain D
3tjm chain A
4piv chain A
4piv chain B
4w82 chain A
4w82 chain B
4w9n chain A
4w9n chain B
4w9n chain C
4w9n chain D
4z49 chain A
4z49 chain B
5c37 chain A
5c37 chain C
6nna chain A
6nna chain B
7mhd chain A
7mhe chain AAA
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S63 DLSRFDAS FFGVHPK 1 9 - - - - - - 9 - - - - - - - - - - - - - S207 FLRLGMLS PEGTCKA 10 1384 122 - 62 50 66 59 99 - 108 62 108 99 110 101 75 18 94 38 95 18 S265 EQGVTFPS GDIQEQL 6 275 73 - - - - - 9 - 6 4 45 42 35 32 - - - - 22 7 S286 SAGVAPES FEYIEAH 3 21 6 - - - - - - - 5 2 - - - - 6 2 - - - - T430 LLRASGRT PEAVQKL 1 9 9 - - - - - - - - - - - - - - - - - - - S724 IPEAQWHS SLARTSS 2 44 26 - - - - - - - - - 10 8 - - - - - - - - S725 PEAQWHSS LARTSSA 8 346 6 - - - 43 29 99 - 20 16 10 9 30 29 - - 9 3 30 13 T827 EFPAPRGT PLISPLI 1 6 6 - - - - - - - - - - - - - - - - - - - S831 PRGTPLIS PLIKWDH 8 380 73 - 4 4 - - 36 - 23 12 29 28 43 40 13 3 - - 57 15 S974 RLFDHPES PTPNPTE 9 187 25 - 4 4 11 16 - - 17 11 5 5 22 20 5 1 21 8 12 -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S63 DLSRFDAS FFGVHPK - - - - - - - - - - - S207 FLRLGMLS PEGTCKA 9.8e-37 - -2.8e-3 1.1e-11 - 2.7e-4 1.4e-25 7.9e-10 -0.54 9.9e-12 2.7e-8 S265 EQGVTFPS GDIQEQL -0.019 - - - - - -3.5e-3 -0.69 - - - S286 SAGVAPES FEYIEAH - - - - - - - - - - - T430 LLRASGRT PEAVQKL - - - - - - - - - - - S724 IPEAQWHS SLARTSS - - - - - - - - - - - S725 PEAQWHSS LARTSSA -0.097 - - 0.62 - -6.7e-3 - 0.93 - - -0.23 T827 EFPAPRGT PLISPLI - - - - - - - - - - - S831 PRGTPLIS PLIKWDH 0.022 - - - - -0.092 0.82 0.089 - - 1.5e-5 S974 RLFDHPES PTPNPTE 1.1e-3 - - - - - - 1.1e-3 - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S63
S207
S265
S286
T430
S724
S725
T827
S831
S974
T976
T980
T1120
S1174
S1221
S1261
S1411
T1420
S1550
S1584
T1593
S1594
S1597
S1727
S1877
S1942
T1943
S2123
S2198
T2204
S2236
S2239
T2434
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S63 S207 S265 S286 T430 S724 S725 T827 S831 S974 T976 T980 T1120 S1174 S1221 S1261 S1411 T1420 S1550 S1584 T1593 S1594 S1597 S1727 S1877 S1942 T1943 S2123 S2198 T2204 S2236 S2239 T2434 protein RNA SCNV methylation CCRCC S63 S207 S265 S286 T430 S724 S725 T827 S831 S974 T976 T980 T1120 S1174 S1221 S1261 S1411 T1420 S1550 S1584 T1593 S1594 S1597 S1727 S1877 S1942 T1943 S2123 S2198 T2204 S2236 S2239 T2434 protein RNA SCNV methylation COAD S63 S207 S265 S286 T430 S724 S725 T827 S831 S974 T976 T980 T1120 S1174 S1221 S1261 S1411 T1420 S1550 S1584 T1593 S1594 S1597 S1727 S1877 S1942 T1943 S2123 S2198 T2204 S2236 S2239 T2434 protein RNA SCNV methylation GBM S63 S207 S265 S286 T430 S724 S725 T827 S831 S974 T976 T980 T1120 S1174 S1221 S1261 S1411 T1420 S1550 S1584 T1593 S1594 S1597 S1727 S1877 S1942 T1943 S2123 S2198 T2204 S2236 S2239 T2434 protein RNA SCNV methylation HNSCC S63 S207 S265 S286 T430 S724 S725 T827 S831 S974 T976 T980 T1120 S1174 S1221 S1261 S1411 T1420 S1550 S1584 T1593 S1594 S1597 S1727 S1877 S1942 T1943 S2123 S2198 T2204 S2236 S2239 T2434 protein RNA SCNV methylation LSCC S63 S207 S265 S286 T430 S724 S725 T827 S831 S974 T976 T980 T1120 S1174 S1221 S1261 S1411 T1420 S1550 S1584 T1593 S1594 S1597 S1727 S1877 S1942 T1943 S2123 S2198 T2204 S2236 S2239 T2434 protein RNA SCNV methylation LUAD S63 S207 S265 S286 T430 S724 S725 T827 S831 S974 T976 T980 T1120 S1174 S1221 S1261 S1411 T1420 S1550 S1584 T1593 S1594 S1597 S1727 S1877 S1942 T1943 S2123 S2198 T2204 S2236 S2239 T2434 protein RNA SCNV methylation OV S63 S207 S265 S286 T430 S724 S725 T827 S831 S974 T976 T980 T1120 S1174 S1221 S1261 S1411 T1420 S1550 S1584 T1593 S1594 S1597 S1727 S1877 S1942 T1943 S2123 S2198 T2204 S2236 S2239 T2434 protein RNA SCNV methylation PDAC S63 S207 S265 S286 T430 S724 S725 T827 S831 S974 T976 T980 T1120 S1174 S1221 S1261 S1411 T1420 S1550 S1584 T1593 S1594 S1597 S1727 S1877 S1942 T1943 S2123 S2198 T2204 S2236 S2239 T2434 protein RNA SCNV methylation UCEC S63 S207 S265 S286 T430 S724 S725 T827 S831 S974 T976 T980 T1120 S1174 S1221 S1261 S1411 T1420 S1550 S1584 T1593 S1594 S1597 S1727 S1877 S1942 T1943 S2123 S2198 T2204 S2236 S2239 T2434 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S63
S207
S265
S286
T430
S724
S725
T827
S831
S974
T976
T980
T1120
S1174
S1221
S1261
S1411
T1420
S1550
S1584
T1593
S1594
S1597
S1727
S1877
S1942
T1943
S2123
S2198
T2204
S2236
S2239
T2434
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S63
S207
S265
S286
T430
S724
S725
T827
S831
S974
T976
T980
T1120
S1174
S1221
S1261
S1411
T1420
S1550
S1584
T1593
S1594
S1597
S1727
S1877
S1942
T1943
S2123
S2198
T2204
S2236
S2239
T2434
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.