Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1h6g chain A
1h6g chain B
4ehp chain B
4igg chain A
4igg chain B
6upv chain L
6upv chain M
6v2o chain C
6v2p chain C
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T42 QVTTLVNT NSKGPSN 5 123 - - 5 4 35 28 27 - - - - - 8 8 - - 5 3 - - S44 TTLVNTNS KGPSNKK 7 246 - - - - 21 24 81 - 11 7 - - 4 4 7 - 52 23 12 - S117 EFADDPCS SVKRGNM 1 16 - - 12 4 - - - - - - - - - - - - - - - - S118 FADDPCSS VKRGNMV 7 193 - - - - 4 5 46 - - - 10 10 8 8 15 2 10 3 66 6 Y177 EQDLGIQY KALKPEV 3 42 17 - - - - - - - - - 5 5 - - - - - - 6 9 T262 ISNAAQAT ASDDASQ 2 33 - - 13 11 - - 9 - - - - - - - - - - - - - S268 ATASDDAS QHQGGGG 6 169 15 - 45 35 5 12 - - 12 7 10 10 10 8 - - - - - - Y280 GGGGELAY ALNNFDK 3 25 - - - - - - 9 - - - 5 3 4 4 - - - - - - S295 QIIVDPLS FSEERFR 10 891 79 - 59 40 18 18 36 - 58 35 64 58 106 97 29 5 74 32 65 18 S297 IVDPLSFS EERFRPS 9 794 22 - 84 61 28 26 54 - 68 39 54 50 63 57 - - 70 31 71 16
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T42 QVTTLVNT NSKGPSN -1.3e-3 - - -1.3e-3 - - - - - - - S44 TTLVNTNS KGPSNKK -0.04 - - -7.0e-4 - - - - - 0.63 - S117 EFADDPCS SVKRGNM - - - - - - - - - - - S118 FADDPCSS VKRGNMV - - - - - - - - - - - Y177 EQDLGIQY KALKPEV - - - - - - - - - - - T262 ISNAAQAT ASDDASQ - - - - - - - - - - - S268 ATASDDAS QHQGGGG 0.65 - 0.65 - - - - - - - - Y280 GGGGELAY ALNNFDK - - - - - - - - - - - S295 QIIVDPLS FSEERFR -0.23 - -3.2e-3 - - -0.18 -0.1 0.051 - -0.68 0.14 S297 IVDPLSFS EERFRPS -9.5e-4 - 0.64 -0.085 - -4.2e-3 -1.8e-7 -0.33 - -0.011 4.1e-5
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T42
S44
S117
S118
Y177
T262
S268
Y280
S295
S297
S361
S366
S439
S453
S455
S477
S558
Y619
T634
S641
T645
S652
T654
S655
T658
S690
S696
S740
S770
S817
S846
S851
S858
S898
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T42 S44 S117 S118 Y177 T262 S268 Y280 S295 S297 S361 S366 S439 S453 S455 S477 S558 Y619 T634 S641 T645 S652 T654 S655 T658 S690 S696 S740 S770 S817 S846 S851 S858 S898 protein RNA SCNV methylation CCRCC T42 S44 S117 S118 Y177 T262 S268 Y280 S295 S297 S361 S366 S439 S453 S455 S477 S558 Y619 T634 S641 T645 S652 T654 S655 T658 S690 S696 S740 S770 S817 S846 S851 S858 S898 protein RNA SCNV methylation COAD T42 S44 S117 S118 Y177 T262 S268 Y280 S295 S297 S361 S366 S439 S453 S455 S477 S558 Y619 T634 S641 T645 S652 T654 S655 T658 S690 S696 S740 S770 S817 S846 S851 S858 S898 protein RNA SCNV methylation GBM T42 S44 S117 S118 Y177 T262 S268 Y280 S295 S297 S361 S366 S439 S453 S455 S477 S558 Y619 T634 S641 T645 S652 T654 S655 T658 S690 S696 S740 S770 S817 S846 S851 S858 S898 protein RNA SCNV methylation HNSCC T42 S44 S117 S118 Y177 T262 S268 Y280 S295 S297 S361 S366 S439 S453 S455 S477 S558 Y619 T634 S641 T645 S652 T654 S655 T658 S690 S696 S740 S770 S817 S846 S851 S858 S898 protein RNA SCNV methylation LSCC T42 S44 S117 S118 Y177 T262 S268 Y280 S295 S297 S361 S366 S439 S453 S455 S477 S558 Y619 T634 S641 T645 S652 T654 S655 T658 S690 S696 S740 S770 S817 S846 S851 S858 S898 protein RNA SCNV methylation LUAD T42 S44 S117 S118 Y177 T262 S268 Y280 S295 S297 S361 S366 S439 S453 S455 S477 S558 Y619 T634 S641 T645 S652 T654 S655 T658 S690 S696 S740 S770 S817 S846 S851 S858 S898 protein RNA SCNV methylation OV T42 S44 S117 S118 Y177 T262 S268 Y280 S295 S297 S361 S366 S439 S453 S455 S477 S558 Y619 T634 S641 T645 S652 T654 S655 T658 S690 S696 S740 S770 S817 S846 S851 S858 S898 protein RNA SCNV methylation PDAC T42 S44 S117 S118 Y177 T262 S268 Y280 S295 S297 S361 S366 S439 S453 S455 S477 S558 Y619 T634 S641 T645 S652 T654 S655 T658 S690 S696 S740 S770 S817 S846 S851 S858 S898 protein RNA SCNV methylation UCEC T42 S44 S117 S118 Y177 T262 S268 Y280 S295 S297 S361 S366 S439 S453 S455 S477 S558 Y619 T634 S641 T645 S652 T654 S655 T658 S690 S696 S740 S770 S817 S846 S851 S858 S898 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T42
S44
S117
S118
Y177
T262
S268
Y280
S295
S297
S361
S366
S439
S453
S455
S477
S558
Y619
T634
S641
T645
S652
T654
S655
T658
S690
S696
S740
S770
S817
S846
S851
S858
S898
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
T42
S44
S117
S118
Y177
T262
S268
Y280
S295
S297
S361
S366
S439
S453
S455
S477
S558
Y619
T634
S641
T645
S652
T654
S655
T658
S690
S696
S740
S770
S817
S846
S851
S858
S898
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.