Protein: ENSP00000305560
Gene: RREB1

LinkedOmicsKB © 2022-2023 Zhang Lab

RREB1:
ras responsive element binding protein 1

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S36KVTENGGSPQGIKSP91415122-10380898190-1086210899110101--105449518
S42GSPQGIKSPSKPPGP895254-785899--10862746810192--105447218
S111KSLSSASSLDRHMLV342--------6355------194
T155EKDPNSATATAPPSP17------------------7-
S161ATATAPPSPLKRRRL91372113-82719710090-108621089910697--88389518
S175LSSKRKLSHDAESER981050-2416868499-704544412624--82356618
S180KLSHDAESEREDPAP718116-1212----6435321412--5231-
T229GLETHMETHSDNPLR512243-1210----159131244------
S231ETHMETHSDNPLRCD5103----11718-53------52466
T351GQEKPQATPLPGDAL257----------54------435
Showing 1 to 10 of 57 rows
102550100
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S36KVTENGGSPQGIKSP8e-10--5.7e-253.1e-4-0.264.1e-321.5e-29--5.3e-124.0e-4
S42GSPQGIKSPSKPPGP2.6e-19-0.07---0.0718.2e-172.7e-16-0.0742.2e-4
S111KSLSSASSLDRHMLV-----------
T155EKDPNSATATAPPSP-----------
S161ATATAPPSPLKRRRL5.7e-33-3.4e-142e-18-0.31.9e-198.1e-4--0.0471.0e-4
S175LSSKRKLSHDAESER0.035--0.0361.8e-6--0.22.2e-70.36--3.1e-65.7e-3
S180KLSHDAESEREDPAP2.3e-7-----2.3e-7----
T229GLETHMETHSDNPLR-----------
S231ETHMETHSDNPLRCD-----------
T351GQEKPQATPLPGDAL-----------
Showing 1 to 10 of 57 rows
102550100
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS36S42S111T155S161S175S180T229S231T351S411S413S522T523S534S539S541S578S669S694S848S903S921T952T1114T1120T1121S1122S1134S1135S1140T1142S1167S1174S1175S1180T1199T1204S1219S1225S1238S1271S1273T1315T1318S1320S1356S1357S1360T1448S1455T1471S1475S1479S1575S1642S1653proteinRNASCNVmethylationCCRCCS36S42S111T155S161S175S180T229S231T351S411S413S522T523S534S539S541S578S669S694S848S903S921T952T1114T1120T1121S1122S1134S1135S1140T1142S1167S1174S1175S1180T1199T1204S1219S1225S1238S1271S1273T1315T1318S1320S1356S1357S1360T1448S1455T1471S1475S1479S1575S1642S1653proteinRNASCNVmethylationCOADS36S42S111T155S161S175S180T229S231T351S411S413S522T523S534S539S541S578S669S694S848S903S921T952T1114T1120T1121S1122S1134S1135S1140T1142S1167S1174S1175S1180T1199T1204S1219S1225S1238S1271S1273T1315T1318S1320S1356S1357S1360T1448S1455T1471S1475S1479S1575S1642S1653proteinRNASCNVmethylationGBMS36S42S111T155S161S175S180T229S231T351S411S413S522T523S534S539S541S578S669S694S848S903S921T952T1114T1120T1121S1122S1134S1135S1140T1142S1167S1174S1175S1180T1199T1204S1219S1225S1238S1271S1273T1315T1318S1320S1356S1357S1360T1448S1455T1471S1475S1479S1575S1642S1653proteinRNASCNVmethylationHNSCCS36S42S111T155S161S175S180T229S231T351S411S413S522T523S534S539S541S578S669S694S848S903S921T952T1114T1120T1121S1122S1134S1135S1140T1142S1167S1174S1175S1180T1199T1204S1219S1225S1238S1271S1273T1315T1318S1320S1356S1357S1360T1448S1455T1471S1475S1479S1575S1642S1653proteinRNASCNVmethylationLSCCS36S42S111T155S161S175S180T229S231T351S411S413S522T523S534S539S541S578S669S694S848S903S921T952T1114T1120T1121S1122S1134S1135S1140T1142S1167S1174S1175S1180T1199T1204S1219S1225S1238S1271S1273T1315T1318S1320S1356S1357S1360T1448S1455T1471S1475S1479S1575S1642S1653proteinRNASCNVmethylationLUADS36S42S111T155S161S175S180T229S231T351S411S413S522T523S534S539S541S578S669S694S848S903S921T952T1114T1120T1121S1122S1134S1135S1140T1142S1167S1174S1175S1180T1199T1204S1219S1225S1238S1271S1273T1315T1318S1320S1356S1357S1360T1448S1455T1471S1475S1479S1575S1642S1653proteinRNASCNVmethylationOVS36S42S111T155S161S175S180T229S231T351S411S413S522T523S534S539S541S578S669S694S848S903S921T952T1114T1120T1121S1122S1134S1135S1140T1142S1167S1174S1175S1180T1199T1204S1219S1225S1238S1271S1273T1315T1318S1320S1356S1357S1360T1448S1455T1471S1475S1479S1575S1642S1653proteinRNASCNVmethylationPDACS36S42S111T155S161S175S180T229S231T351S411S413S522T523S534S539S541S578S669S694S848S903S921T952T1114T1120T1121S1122S1134S1135S1140T1142S1167S1174S1175S1180T1199T1204S1219S1225S1238S1271S1273T1315T1318S1320S1356S1357S1360T1448S1455T1471S1475S1479S1575S1642S1653proteinRNASCNVmethylationUCECS36S42S111T155S161S175S180T229S231T351S411S413S522T523S534S539S541S578S669S694S848S903S921T952T1114T1120T1121S1122S1134S1135S1140T1142S1167S1174S1175S1180T1199T1204S1219S1225S1238S1271S1273T1315T1318S1320S1356S1357S1360T1448S1455T1471S1475S1479S1575S1642S1653proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

Loading, please wait
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.