SF3B3: splicing factor 3b subunit 3
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
5ife chain A
5o9z chain w
5z56 chain 3
5z57 chain 3
5z58 chain 3
5zya chain A
6ah0 chain 3
6ahd chain 3
6en4 chain A
6ff4 chain v
6ff7 chain v
6qx9 chain B3
6y50 chain v
6y5q chain v
7abg chain E
7abh chain E
7abi chain E
7b0i chain A
7b91 chain A
7b92 chain A
7b9c chain A
7dvq chain 3
7evn chain A
7evo chain 3
7kts chain S
7omf chain A
7onb chain A
7opi chain A
7q3l chain C
7q4o chain C
7q4p chain C
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S156 AARLTISS PLEAHKA 9 198 48 - 4 4 - - 9 - 27 17 20 19 4 3 6 2 5 2 23 5 S1086 RGLLNGAS QKAEVIM 2 24 9 - - - - - - - - - - - - - - - 10 5 - - T1200 VSEELDRT PPEVSKK 10 929 100 - 44 35 46 43 18 - 90 53 98 90 75 67 64 13 20 6 60 7
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S156 AARLTISS PLEAHKA 3.1e-6 - - - - 6.7e-5 0.009 - - - - S1086 RGLLNGAS QKAEVIM - - - - - - - - - - - T1200 VSEELDRT PPEVSKK 1.2e-40 - -0.53 1.3e-4 - 4.5e-15 1.4e-25 3.3e-21 0.081 - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S156
S1086
T1200
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S156 S1086 T1200 protein RNA SCNV methylation CCRCC S156 S1086 T1200 protein RNA SCNV methylation COAD S156 S1086 T1200 protein RNA SCNV methylation GBM S156 S1086 T1200 protein RNA SCNV methylation HNSCC S156 S1086 T1200 protein RNA SCNV methylation LSCC S156 S1086 T1200 protein RNA SCNV methylation LUAD S156 S1086 T1200 protein RNA SCNV methylation OV S156 S1086 T1200 protein RNA SCNV methylation PDAC S156 S1086 T1200 protein RNA SCNV methylation UCEC S156 S1086 T1200 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S156
S1086
T1200
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S156
S1086
T1200
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.