YWHAG: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2b05 chain A
2b05 chain B
2b05 chain C
2b05 chain D
2b05 chain E
2b05 chain F
3uzd chain A
4e2e chain A
4j6s chain A
4j6s chain B
4j6s chain C
4j6s chain D
4o46 chain A
4o46 chain B
4o46 chain C
4o46 chain D
4o46 chain E
4o46 chain F
5d3e chain A
5d3e chain B
5d3e chain E
5d3e chain F
5d3e chain I
5d3e chain J
6a5s chain A
6a5s chain B
6a5s chain D
6a5s chain G
6byj chain A
6byj chain B
6byj chain C
6byj chain D
6byj chain E
6byj chain F
6byl chain A
6byl chain B
6byl chain C
6byl chain D
6byl chain E
6byl chain F
6bzd chain A
6bzd chain B
6bzd chain C
6bzd chain D
6fel chain A
6fel chain B
6fel chain C
6fel chain D
6gkf chain A
6gkf chain B
6gkf chain C
6gkf chain D
6gkf chain E
6gkf chain F
6gkf chain G
6gkf chain H
6gkg chain A
6gkg chain B
6gkg chain C
6gkg chain D
6gkg chain E
6gkg chain F
6gkg chain G
6gkg chain H
6s9k chain A
6sad chain A
6sad chain B
6y4k chain A
6y4k chain B
6y6b chain A
6y6b chain B
6zbt chain A
6zbt chain B
6zbt chain C
6zbt chain D
6zc9 chain A
6zc9 chain B
6zc9 chain C
6zc9 chain D
7a6r chain A
7a6r chain B
7a6r chain C
7a6r chain D
7a6y chain A
7a6y chain B
7a6y chain C
7a6y chain D
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S38 TELNEPLS NEERNLL 1 6 - - - - - - - - - - - - - - - - - - 6 - T70 ISSIEQKT SADGNEK 3 26 7 - - - - - - - - - - - 5 4 - - 7 3 - - S71 SSIEQKTS ADGNEKK 8 601 82 - 15 14 - - 90 - 22 14 60 56 51 44 - - 52 23 65 13 S102 AVCQDVLS LLDNYLI 1 8 - - - - - - 8 - - - - - - - - - - - - - S113 NYLIKNCS ETQYESK 2 54 - - - - 11 7 36 - - - - - - - - - - - - - Y117 KNCSETQY ESKVFYL 3 86 - - - - - - 54 - 15 12 - - - - - - 3 2 - - S119 CSETQYES KVFYLKM 3 54 - - - - 3 6 36 - 6 3 - - - - - - - - - - Y133 MKGDYYRY LAEVATG 2 190 - - - - - - 99 - 56 35 - - - - - - - - - - T139 RYLAEVAT GEKRATV 3 71 8 - - - - - 45 - 11 7 - - - - - - - - - - T145 ATGEKRAT VVESSEK 1 9 - - - - - - - - - - - - - - 7 2 - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S38 TELNEPLS NEERNLL - - - - - - - - - - - T70 ISSIEQKT SADGNEK - - - - - - - - - - - S71 SSIEQKTS ADGNEKK 9.3e-3 - - - - -0.43 2.1e-10 5.2e-10 - -6.9e-5 -0.047 S102 AVCQDVLS LLDNYLI - - - - - - - - - - - S113 NYLIKNCS ETQYESK - - - - - - - - - - - Y117 KNCSETQY ESKVFYL - - - - - - - - - - - S119 CSETQYES KVFYLKM - - - - - - - - - - - Y133 MKGDYYRY LAEVATG -3.8e-4 - - - - -3.8e-4 - - - - - T139 RYLAEVAT GEKRATV - - - - - - - - - - - T145 ATGEKRAT VVESSEK - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S38
T70
S71
S102
S113
Y117
S119
Y133
T139
T145
S149
S155
T210
S215
S235
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S38 T70 S71 S102 S113 Y117 S119 Y133 T139 T145 S149 S155 T210 S215 S235 protein RNA SCNV methylation CCRCC S38 T70 S71 S102 S113 Y117 S119 Y133 T139 T145 S149 S155 T210 S215 S235 protein RNA SCNV methylation COAD S38 T70 S71 S102 S113 Y117 S119 Y133 T139 T145 S149 S155 T210 S215 S235 protein RNA SCNV methylation GBM S38 T70 S71 S102 S113 Y117 S119 Y133 T139 T145 S149 S155 T210 S215 S235 protein RNA SCNV methylation HNSCC S38 T70 S71 S102 S113 Y117 S119 Y133 T139 T145 S149 S155 T210 S215 S235 protein RNA SCNV methylation LSCC S38 T70 S71 S102 S113 Y117 S119 Y133 T139 T145 S149 S155 T210 S215 S235 protein RNA SCNV methylation LUAD S38 T70 S71 S102 S113 Y117 S119 Y133 T139 T145 S149 S155 T210 S215 S235 protein RNA SCNV methylation OV S38 T70 S71 S102 S113 Y117 S119 Y133 T139 T145 S149 S155 T210 S215 S235 protein RNA SCNV methylation PDAC S38 T70 S71 S102 S113 Y117 S119 Y133 T139 T145 S149 S155 T210 S215 S235 protein RNA SCNV methylation UCEC S38 T70 S71 S102 S113 Y117 S119 Y133 T139 T145 S149 S155 T210 S215 S235 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S38
T70
S71
S102
S113
Y117
S119
Y133
T139
T145
S149
S155
T210
S215
S235
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S38
T70
S71
S102
S113
Y117
S119
Y133
T139
T145
S149
S155
T210
S215
S235
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.