YEATS2: YEATS domain containing 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
5iql chain A
5xnv chain A
6lsd chain A
6lsd chain B
7eie chain A
7eie chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S118 AIKKFLES PSRSSSP 10 1239 88 - 85 64 68 75 81 - 81 43 98 90 97 89 25 8 100 41 88 18 S120 KKFLESPS RSSSPAN 9 727 73 - 65 44 4 5 36 - 48 31 98 90 74 68 - - 57 26 5 3 S122 FLESPSRS SSPANQR 7 129 25 - 9 8 - - - - 5 4 14 12 17 16 - - 9 3 7 - S123 LESPSRSS SPANQRA 7 172 9 - 8 8 - - 9 - - - 25 23 9 8 - - 8 5 53 7 S124 ESPSRSSS PANQRAE 8 370 17 - 5 4 25 29 64 - - - 30 27 43 37 54 9 - - 24 2 T132 PANQRAET PSANHSE 2 54 - - - - - - 37 - - - - - - - 12 5 - - - - S144 HSESDSLS QHNDFLS 1 18 - - - - - - 18 - - - - - - - - - - - - - S157 LSDKDNNS NMDIEER 7 459 31 - 12 10 - - 9 - - - 98 90 88 80 - - 3 2 34 2 S367 PAPVKASS PIKQSHE 2 215 - - - - 89 82 - - - - - - - - 37 7 - - - - S388 VEKGFPAS TEAERHT 1 9 - - - - - - 9 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S118 AIKKFLES PSRSSSP 1.4e-6 - -4.3e-4 1.1e-12 - 2.9e-10 1.8e-17 -0.16 - -0.3 -3.6e-3 S120 KKFLESPS RSSSPAN -4.7e-3 - 0.029 - - -0.35 -0.1 -6e-9 - -0.9 - S122 FLESPSRS SSPANQR - - - - - - - - - - - S123 LESPSRSS SPANQRA 0.052 - - - - - 0.052 - - - - S124 ESPSRSSS PANQRAE 2.5e-3 - - 0.43 - - 0.18 1.9e-3 - - - T132 PANQRAET PSANHSE - - - - - - - - - - - S144 HSESDSLS QHNDFLS - - - - - - - - - - - S157 LSDKDNNS NMDIEER 1.3e-27 - - - - - 5.5e-18 1.4e-11 - - - S367 PAPVKASS PIKQSHE 2.2e-14 - - 2.3e-14 - - - - - - - S388 VEKGFPAS TEAERHT - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S118
S120
S122
S123
S124
T132
S144
S157
S367
S388
T395
S403
T407
S447
S465
S468
T469
S471
S473
T478
T482
T514
S516
S519
S531
T534
S536
S575
S610
S627
T634
S868
T1009
S1043
T1219
T1255
S1259
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S118 S120 S122 S123 S124 T132 S144 S157 S367 S388 T395 S403 T407 S447 S465 S468 T469 S471 S473 T478 T482 T514 S516 S519 S531 T534 S536 S575 S610 S627 T634 S868 T1009 S1043 T1219 T1255 S1259 protein RNA SCNV methylation CCRCC S118 S120 S122 S123 S124 T132 S144 S157 S367 S388 T395 S403 T407 S447 S465 S468 T469 S471 S473 T478 T482 T514 S516 S519 S531 T534 S536 S575 S610 S627 T634 S868 T1009 S1043 T1219 T1255 S1259 protein RNA SCNV methylation COAD S118 S120 S122 S123 S124 T132 S144 S157 S367 S388 T395 S403 T407 S447 S465 S468 T469 S471 S473 T478 T482 T514 S516 S519 S531 T534 S536 S575 S610 S627 T634 S868 T1009 S1043 T1219 T1255 S1259 protein RNA SCNV methylation GBM S118 S120 S122 S123 S124 T132 S144 S157 S367 S388 T395 S403 T407 S447 S465 S468 T469 S471 S473 T478 T482 T514 S516 S519 S531 T534 S536 S575 S610 S627 T634 S868 T1009 S1043 T1219 T1255 S1259 protein RNA SCNV methylation HNSCC S118 S120 S122 S123 S124 T132 S144 S157 S367 S388 T395 S403 T407 S447 S465 S468 T469 S471 S473 T478 T482 T514 S516 S519 S531 T534 S536 S575 S610 S627 T634 S868 T1009 S1043 T1219 T1255 S1259 protein RNA SCNV methylation LSCC S118 S120 S122 S123 S124 T132 S144 S157 S367 S388 T395 S403 T407 S447 S465 S468 T469 S471 S473 T478 T482 T514 S516 S519 S531 T534 S536 S575 S610 S627 T634 S868 T1009 S1043 T1219 T1255 S1259 protein RNA SCNV methylation LUAD S118 S120 S122 S123 S124 T132 S144 S157 S367 S388 T395 S403 T407 S447 S465 S468 T469 S471 S473 T478 T482 T514 S516 S519 S531 T534 S536 S575 S610 S627 T634 S868 T1009 S1043 T1219 T1255 S1259 protein RNA SCNV methylation OV S118 S120 S122 S123 S124 T132 S144 S157 S367 S388 T395 S403 T407 S447 S465 S468 T469 S471 S473 T478 T482 T514 S516 S519 S531 T534 S536 S575 S610 S627 T634 S868 T1009 S1043 T1219 T1255 S1259 protein RNA SCNV methylation PDAC S118 S120 S122 S123 S124 T132 S144 S157 S367 S388 T395 S403 T407 S447 S465 S468 T469 S471 S473 T478 T482 T514 S516 S519 S531 T534 S536 S575 S610 S627 T634 S868 T1009 S1043 T1219 T1255 S1259 protein RNA SCNV methylation UCEC S118 S120 S122 S123 S124 T132 S144 S157 S367 S388 T395 S403 T407 S447 S465 S468 T469 S471 S473 T478 T482 T514 S516 S519 S531 T534 S536 S575 S610 S627 T634 S868 T1009 S1043 T1219 T1255 S1259 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S118
S120
S122
S123
S124
T132
S144
S157
S367
S388
T395
S403
T407
S447
S465
S468
T469
S471
S473
T478
T482
T514
S516
S519
S531
T534
S536
S575
S610
S627
T634
S868
T1009
S1043
T1219
T1255
S1259
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S118
S120
S122
S123
S124
T132
S144
S157
S367
S388
T395
S403
T407
S447
S465
S468
T469
S471
S473
T478
T482
T514
S516
S519
S531
T534
S536
S575
S610
S627
T634
S868
T1009
S1043
T1219
T1255
S1259
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.