ASL: argininosuccinate lyase
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1aos chain A
1aos chain B
1k62 chain A
1k62 chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S83 QGTFKLNS NDEDIHT 1 8 - - 4 4 - - - - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S83 QGTFKLNS NDEDIHT - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S83 protein RNA SCNV methylation CCRCC S83 protein RNA SCNV methylation COAD S83 protein RNA SCNV methylation GBM S83 protein RNA SCNV methylation HNSCC S83 protein RNA SCNV methylation LSCC S83 protein RNA SCNV methylation LUAD S83 protein RNA SCNV methylation OV S83 protein RNA SCNV methylation PDAC S83 protein RNA SCNV methylation UCEC S83 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S83
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
EPHA7 S83 - - - - - - - - - - - EPHA8 S83 - - - - - - - - - - - EPHA3 S83 - - - - - - - - - - - EPHA6 S83 - - - - - - - - - - - EPHA4 S83 - - - - - - - - - - - EPHA2 S83 - - - - - - - - - - - EPHA1 S83 - - - - - - - - - - - EIF2AK4 S83 - - - - - - - - - - - EPHA10 S83 - - - - - - - - - - - EPHA5 S83 - - - - - - - - - - -
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S83
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
ALPI S83 - - - - - - - - - - - ALPL S83 - - - - - - - - - - - ACP5 S83 - - - - - - - - - - - ALPG S83 - - - - - - - - - - - ACP6 S83 - - - - - - - - - - - ACP4 S83 - - - - - - - - - - - ACP2 S83 - - - - - - - - - - - ACP1 S83 - - - - - - - - - - - ACP3 S83 - - - - - - - - - - - ACP7 S83 - - - - - - - - - - -
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.