Protein: ENSP00000307265
Gene: IRF2BP1

LinkedOmicsKB © 2022-2023 Zhang Lab

IRF2BP1:
interferon regulatory factor 2 binding protein 1

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S66HVLPEGRSPGPPALK101553122-103809710099-10862108991101018319105449518
S117DRYDRATSSGRLPLP16------------------6-
S125SGRLPLPSPALEYTL10118880-3835756981-7036103959689781592378316
S186LTLAPGLSPARPLFG101220104-10380221454-10259108991101013110105446113
S311PGKALASSGFKYLEY331------------9871--6-
Y354AEALPQQYPEPAPAA510732-1816------141344--42--
S371GPPPRAPSRNLAPTP101309122-6848706494-98609889109100367101428518
T377PSRNLAPTPRRRKAS101133114-7452241289-6942103959384541279308918
S384TPRRRKASPEPEGEA101553122-103809710099-10862108991101018319105449518
Y412WVAPGGPYSAETPGV18--------------53----
Showing 1 to 10 of 22 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S66HVLPEGRSPGPPALK-2.3e-10-0.002-0.64--4.3e-10-8.1e-3-1.1e-13-0.280.018-3.7e-8
S117DRYDRATSSGRLPLP-----------
S125SGRLPLPSPALEYTL-9e-16-0.29-1.1e-6--9.0e-6-0.041-7.4e-22-0.0140.15-0.07
S186LTLAPGLSPARPLFG-1.2e-16-2.2e-4-0.012--1.4e-13-7.9e-5-1.3e-100.43-8.7e-12-0.43
S311PGKALASSGFKYLEY-----------
Y354AEALPQQYPEPAPAA-----------
S371GPPPRAPSRNLAPTP-8.8e-18-3.9e-8-0.091--2.3e-3-1.3e-5-4.6e-22--6e-8-5.3e-5
T377PSRNLAPTPRRRKAS4.7e-6-0.0210.078-0.0113.2e-11-0.70.02-0.0130.81
S384TPRRRKASPEPEGEA6.6e-5--6e-218.1e-28--0.471.5e-275.1e-120.13-7.5e-15-0.025
Y412WVAPGGPYSAETPGV-----------
Showing 1 to 10 of 22 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS66S117S125S186S311Y354S371T377S384Y412T416S421S436S453S457S478T480S487S491T493T496T570proteinRNASCNVmethylationCCRCCS66S117S125S186S311Y354S371T377S384Y412T416S421S436S453S457S478T480S487S491T493T496T570proteinRNASCNVmethylationCOADS66S117S125S186S311Y354S371T377S384Y412T416S421S436S453S457S478T480S487S491T493T496T570proteinRNASCNVmethylationGBMS66S117S125S186S311Y354S371T377S384Y412T416S421S436S453S457S478T480S487S491T493T496T570proteinRNASCNVmethylationHNSCCS66S117S125S186S311Y354S371T377S384Y412T416S421S436S453S457S478T480S487S491T493T496T570proteinRNASCNVmethylationLSCCS66S117S125S186S311Y354S371T377S384Y412T416S421S436S453S457S478T480S487S491T493T496T570proteinRNASCNVmethylationLUADS66S117S125S186S311Y354S371T377S384Y412T416S421S436S453S457S478T480S487S491T493T496T570proteinRNASCNVmethylationOVS66S117S125S186S311Y354S371T377S384Y412T416S421S436S453S457S478T480S487S491T493T496T570proteinRNASCNVmethylationPDACS66S117S125S186S311Y354S371T377S384Y412T416S421S436S453S457S478T480S487S491T493T496T570proteinRNASCNVmethylationUCECS66S117S125S186S311Y354S371T377S384Y412T416S421S436S453S457S478T480S487S491T493T496T570proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.