ZNF608: zinc finger protein 608
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S248 KSNGGGAS PFHCGGT 3 61 - - - - - - 45 - - - - - - - 6 2 - - 6 2 T255 SPFHCGGT GSGSVAA 1 8 8 - - - - - - - - - - - - - - - - - - - S421 APPRFCES PTSDLEM 10 616 22 - 17 16 25 20 97 - 17 10 29 26 43 39 71 15 41 15 95 18 T423 PRFCESPT SDLEMRG 8 384 13 - 5 4 - - 9 - 5 4 93 85 65 61 - - 7 3 24 6 S424 RFCESPTS DLEMRGG 8 135 17 - 5 4 - - 9 - 5 4 10 10 14 12 - - 7 3 31 4 S440 GRGKRARS AAAAPGS 3 73 - - - - - - 36 - - - - - 4 4 - - - - 24 5 S473 NGKGRRGS LNASGRR 10 1244 76 - 66 44 80 90 99 - 18 10 108 99 110 101 76 17 97 40 95 18 T481 LNASGRRT PPNCAAE 10 1291 69 - 95 72 69 57 99 - 65 39 98 91 110 101 77 17 87 38 89 18 S493 AAEDIKAS PSSTNKR 1 10 - - - - - - - - - - 5 5 - - - - - - - - S527 GKRVRTNS RSTPTTP 1 8 - - - - - - - - - - - - - - - - - - 5 3
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S248 KSNGGGAS PFHCGGT - - - - - - - - - - - T255 SPFHCGGT GSGSVAA - - - - - - - - - - - S421 APPRFCES PTSDLEM 4.9e-11 - - 0.008 - - 0.83 9.1e-4 0.036 8.6e-5 9.5e-5 T423 PRFCESPT SDLEMRG -4e-15 - - - - - -3.7e-14 -4.0e-4 - - - S424 RFCESPTS DLEMRGG - - - - - - - - - - - S440 GRGKRARS AAAAPGS - - - - - - - - - - - S473 NGKGRRGS LNASGRR -0.93 - 5.2e-8 0.13 - - -1.8e-14 0.69 7.9e-4 -6.4e-10 3.9e-3 T481 LNASGRRT PPNCAAE -0.56 - -0.29 6.7e-3 - -0.04 -9.4e-5 -0.85 0.023 -2.2e-5 1.4e-6 S493 AAEDIKAS PSSTNKR - - - - - - - - - - - S527 GKRVRTNS RSTPTTP - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S248
T255
S421
T423
S424
S440
S473
T481
S493
S527
S529
T530
T533
S548
S549
S591
S596
S603
S627
T636
S782
S829
S895
S936
S943
S951
S963
S964
S1098
T1159
S1270
T1274
T1318
S1366
S1402
S1430
S1453
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S248 T255 S421 T423 S424 S440 S473 T481 S493 S527 S529 T530 T533 S548 S549 S591 S596 S603 S627 T636 S782 S829 S895 S943 S951 S963 S964 S1098 T1159 S1270 T1274 T1318 S1366 S1402 S1430 S1453 protein RNA SCNV methylation CCRCC S248 T255 S421 T423 S424 S440 S473 T481 S493 S527 S529 T530 T533 S548 S549 S591 S596 S603 S627 T636 S782 S829 S895 S943 S951 S963 S964 S1098 T1159 S1270 T1274 T1318 S1366 S1402 S1430 S1453 protein RNA SCNV methylation COAD S248 T255 S421 T423 S424 S440 S473 T481 S493 S527 S529 T530 T533 S548 S549 S591 S596 S603 S627 T636 S782 S829 S895 S943 S951 S963 S964 S1098 T1159 S1270 T1274 T1318 S1366 S1402 S1430 S1453 protein RNA SCNV methylation GBM S248 T255 S421 T423 S424 S440 S473 T481 S493 S527 S529 T530 T533 S548 S549 S591 S596 S603 S627 T636 S782 S829 S895 S943 S951 S963 S964 S1098 T1159 S1270 T1274 T1318 S1366 S1402 S1430 S1453 protein RNA SCNV methylation HNSCC S248 T255 S421 T423 S424 S440 S473 T481 S493 S527 S529 T530 T533 S548 S549 S591 S596 S603 S627 T636 S782 S829 S895 S943 S951 S963 S964 S1098 T1159 S1270 T1274 T1318 S1366 S1402 S1430 S1453 protein RNA SCNV methylation LSCC S248 T255 S421 T423 S424 S440 S473 T481 S493 S527 S529 T530 T533 S548 S549 S591 S596 S603 S627 T636 S782 S829 S895 S943 S951 S963 S964 S1098 T1159 S1270 T1274 T1318 S1366 S1402 S1430 S1453 protein RNA SCNV methylation LUAD S248 T255 S421 T423 S424 S440 S473 T481 S493 S527 S529 T530 T533 S548 S549 S591 S596 S603 S627 T636 S782 S829 S895 S943 S951 S963 S964 S1098 T1159 S1270 T1274 T1318 S1366 S1402 S1430 S1453 protein RNA SCNV methylation OV S248 T255 S421 T423 S424 S440 S473 T481 S493 S527 S529 T530 T533 S548 S549 S591 S596 S603 S627 T636 S782 S829 S895 S943 S951 S963 S964 S1098 T1159 S1270 T1274 T1318 S1366 S1402 S1430 S1453 protein RNA SCNV methylation PDAC S248 T255 S421 T423 S424 S440 S473 T481 S493 S527 S529 T530 T533 S548 S549 S591 S596 S603 S627 T636 S782 S829 S895 S943 S951 S963 S964 S1098 T1159 S1270 T1274 T1318 S1366 S1402 S1430 S1453 protein RNA SCNV methylation UCEC S248 T255 S421 T423 S424 S440 S473 T481 S493 S527 S529 T530 T533 S548 S549 S591 S596 S603 S627 T636 S782 S829 S895 S943 S951 S963 S964 S1098 T1159 S1270 T1274 T1318 S1366 S1402 S1430 S1453 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S248
T255
S421
T423
S424
S440
S473
T481
S493
S527
S529
T530
T533
S548
S549
S591
S596
S603
S627
T636
S782
S829
S895
S936
S943
S951
S963
S964
S1098
T1159
S1270
T1274
T1318
S1366
S1402
S1430
S1453
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S248
T255
S421
T423
S424
S440
S473
T481
S493
S527
S529
T530
T533
S548
S549
S591
S596
S603
S627
T636
S782
S829
S895
S936
S943
S951
S963
S964
S1098
T1159
S1270
T1274
T1318
S1366
S1402
S1430
S1453
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.