Protein: ENSP00000308227
Gene: HMGA1

LinkedOmicsKB © 2022-2023 Zhang Lab

HMGA1:
high mobility group AT-hook 1

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S8MSESSSKSSQPLASK9115082-8262--90-103599889110101153100439518
S9SESSSKSSQPLASKQ101276113-8765474353-1086210896888075169641899
S14KSSQPLASKQEKDGT55516-44----64----7293--
S36PRKQPPVSPGTALVG10141071-65529710099-1086210899101927717105449518
T39QPPVSPGTALVGSQK512636-------1810552319----10-
S44PGTALVGSQKEPSEV101429122-9976736899-1086210899101935314105448718
S49VGSQKEPSEVPTPKR1097697-6453604819-41208377918323484338016
T53KEPSEVPTPKRPRGR101302122-24249710099-85511089910191831968318218
T76AAKTRKTTTTPGRKP125--------------205----
T78KTRKTTTTPGRKPRG72589-----37---5513126314269614
Showing 1 to 10 of 13 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S8MSESSSKSSQPLASK1.5e-11--3e-10--0.0261.1e-171.5e-8-1.2e-70.28
S9SESSSKSSQPLASKQ1.7e-52--3.1e-43.2e-11-2.3e-94.2e-349.3e-200.164e-18-
S14KSSQPLASKQEKDGT-----------
S36PRKQPPVSPGTALVG3.7e-7--5.6e-142.7e-19--3.6e-35.3e-71.6e-59.6e-4-0.353.6e-5
T39QPPVSPGTALVGSQK0.051------0.051---
S44PGTALVGSQKEPSEV5.5e-35--6.5e-84.4e-15-7.3e-147e-291.5e-150.11.4e-5-0.9
S49VGSQKEPSEVPTPKR3.5e-24--2.5e-78.2e-6-1.4e-39.7e-181.4e-18-0.0437.4e-7
T53KEPSEVPTPKRPRGR3.7e-70-0.0137.4e-29-2.9e-151e-327.8e-111.8e-42.1e-50.032
T76AAKTRKTTTTPGRKP-----------
T78KTRKTTTTPGRKPRG2.3e-4-------2.3e-4--
Showing 1 to 10 of 13 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS8S9S14S36T39S44S49T53T76T78S99S102S103proteinRNASCNVmethylationCCRCCS8S9S14S36T39S44S49T53T76T78S99S102S103proteinRNASCNVmethylationCOADS8S9S14S36T39S44S49T53T76T78S99S102S103proteinRNASCNVmethylationGBMS8S9S14S36T39S44S49T53T76T78S99S102S103proteinRNASCNVmethylationHNSCCS8S9S14S36T39S44S49T53T76T78S99S102S103proteinRNASCNVmethylationLSCCS8S9S14S36T39S44S49T53T76T78S99S102S103proteinRNASCNVmethylationLUADS8S9S14S36T39S44S49T53T76T78S99S102S103proteinRNASCNVmethylationOVS8S9S14S36T39S44S49T53T76T78S99S102S103proteinRNASCNVmethylationPDACS8S9S14S36T39S44S49T53T76T78S99S102S103proteinRNASCNVmethylationUCECS8S9S14S36T39S44S49T53T76T78S99S102S103proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

Loading, please wait
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.