LSP1: lymphocyte specific protein 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
3bh8 chain C
4no0 chain C
4no2 chain C
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S6 __MAEASS DPGAEER 1 9 - - - - - - - - - - - - 4 5 - - - - - - S24 LGPTAQWS VEDEEEA 10 1473 113 - 103 80 93 95 98 - 101 59 104 99 110 99 76 16 105 44 60 18 S66 PKQEMLLS LKPSEAP 4 91 - - - - - - - - 13 7 24 24 9 8 - - 5 1 - - S70 MLLSLKPS EAPELDE 4 74 31 - 8 - - - - - - - 10 9 8 8 - - - - - - S85 DEGFGDWS QRPEQRQ 1 26 - - - - - - - - - - 14 12 - - - - - - - - S103 GAQGALDS GEPPQCR 8 496 87 - 54 34 5 12 - - 29 17 50 45 65 58 14 2 16 8 - - S111 GEPPQCRS PEGEQED 10 1529 113 - 100 77 97 100 99 - 108 62 108 99 105 97 83 19 105 44 95 18 Y125 DRPGLHAY EKEDSDE 3 24 8 - - - - - - - - - 4 4 4 4 - - - - - - S130 HAYEKEDS DEVHLEE 10 1483 114 - 99 76 82 85 99 - 102 59 108 99 110 101 83 19 100 41 90 16 S139 EVHLEELS LSKEGPG 10 1034 106 - 86 72 18 18 27 - 52 30 79 73 79 71 75 18 103 43 68 16
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S6 __MAEASS DPGAEER - - - - - - - - - - - S24 LGPTAQWS VEDEEEA -5.9e-3 - 2.1e-13 -1.4e-4 - 0.9 -4.4e-9 -7.2e-6 1 -0.11 0.61 S66 PKQEMLLS LKPSEAP 0.19 - - - - - 0.19 - - - - S70 MLLSLKPS EAPELDE - - - - - - - - - - - S85 DEGFGDWS QRPEQRQ - - - - - - - - - - - S103 GAQGALDS GEPPQCR -0.67 - 1.3e-3 - - 0.13 -4.2e-6 -0.33 - - - S111 GEPPQCRS PEGEQED 7.2e-6 - 8.8e-20 0.059 - 0.098 -4.5e-3 -0.13 0.57 0.015 0.17 Y125 DRPGLHAY EKEDSDE - - - - - - - - - - - S130 HAYEKEDS DEVHLEE 1.8e-22 - 2.2e-19 4.1e-3 - 0.024 -0.64 0.17 1.5e-5 2.8e-11 0.12 S139 EVHLEELS LSKEGPG 8e-21 - 1.3e-14 - - 1.6e-8 -0.04 5.9e-3 0.14 2.4e-13 0.055
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S6
S24
S66
S70
S85
S103
S111
Y125
S130
S139
S141
T175
S177
T184
S188
S189
S193
S204
S208
S214
S218
T240
T244
S252
S257
S262
T269
S276
S282
S292
S295
S306
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S6 S24 S66 S70 S85 S103 S111 Y125 S130 S139 S141 T175 S177 T184 S188 S189 S193 S204 S208 S214 S218 T240 T244 S252 S257 S262 T269 S276 S282 S292 S295 S306 protein RNA SCNV methylation CCRCC S6 S24 S66 S70 S85 S103 S111 Y125 S130 S139 S141 T175 S177 T184 S188 S189 S193 S204 S208 S214 S218 T240 T244 S252 S257 S262 T269 S276 S282 S292 S295 S306 protein RNA SCNV methylation COAD S6 S24 S66 S70 S85 S103 S111 Y125 S130 S139 S141 T175 S177 T184 S188 S189 S193 S204 S208 S214 S218 T240 T244 S252 S257 S262 T269 S276 S282 S292 S295 S306 protein RNA SCNV methylation GBM S6 S24 S66 S70 S85 S103 S111 Y125 S130 S139 S141 T175 S177 T184 S188 S189 S193 S204 S208 S214 S218 T240 T244 S252 S257 S262 T269 S276 S282 S292 S295 S306 protein RNA SCNV methylation HNSCC S6 S24 S66 S70 S85 S103 S111 Y125 S130 S139 S141 T175 S177 T184 S188 S189 S193 S204 S208 S214 S218 T240 T244 S252 S257 S262 T269 S276 S282 S292 S295 S306 protein RNA SCNV methylation LSCC S6 S24 S66 S70 S85 S103 S111 Y125 S130 S139 S141 T175 S177 T184 S188 S189 S193 S204 S208 S214 S218 T240 T244 S252 S257 S262 T269 S276 S282 S292 S295 S306 protein RNA SCNV methylation LUAD S6 S24 S66 S70 S85 S103 S111 Y125 S130 S139 S141 T175 S177 T184 S188 S189 S193 S204 S208 S214 S218 T240 T244 S252 S257 S262 T269 S276 S282 S292 S295 S306 protein RNA SCNV methylation OV S6 S24 S66 S70 S85 S103 S111 Y125 S130 S139 S141 T175 S177 T184 S188 S189 S193 S204 S208 S214 S218 T240 T244 S252 S257 S262 T269 S276 S282 S292 S295 S306 protein RNA SCNV methylation PDAC S6 S24 S66 S70 S85 S103 S111 Y125 S130 S139 S141 T175 S177 T184 S188 S189 S193 S204 S208 S214 S218 T240 T244 S252 S257 S262 T269 S276 S282 S292 S295 S306 protein RNA SCNV methylation UCEC S6 S24 S66 S70 S85 S103 S111 Y125 S130 S139 S141 T175 S177 T184 S188 S189 S193 S204 S208 S214 S218 T240 T244 S252 S257 S262 T269 S276 S282 S292 S295 S306 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S6
S24
S66
S70
S85
S103
S111
Y125
S130
S139
S141
T175
S177
T184
S188
S189
S193
S204
S208
S214
S218
T240
T244
S252
S257
S262
T269
S276
S282
S292
S295
S306
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S6
S24
S66
S70
S85
S103
S111
Y125
S130
S139
S141
T175
S177
T184
S188
S189
S193
S204
S208
S214
S218
T240
T244
S252
S257
S262
T269
S276
S282
S292
S295
S306
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.