Protein: ENSP00000308532
Gene: DBN1

LinkedOmicsKB © 2022-2023 Zhang Lab

DBN1:
drebrin 1

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S134GAIGQRLSNGLARLS888454-5840--64-75418376110101--6625829
S141SNGLARLSSPVLHRL822813-44--44-12634322320--4131-
S142NGLARLSSPVLHRLR81243113-10380--99-1086210899110101--104439518
S255KRRLKEQSIFGDHRD19------9-------------
S272EETHMKKSESEVEEA5230------99-3521--44--514714
S274THMKKSESEVEEAAA8102586-10380--81-664298909386--101424314
S307VASASAGSCDVPSPF155------55-------------
S312AGSCDVPSPFNHRPG315916-----99-2717----------
S320PFNHRPGSHLDSHRR41577-----99-117------249--
S324RPGSHLDSHRRMAPT267------60---------52--
Showing 1 to 10 of 25 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S134GAIGQRLSNGLARLS1.4e-20-1.9e-9--2.2e-50.33.0e-5-8.9e-8-
S141SNGLARLSSPVLHRL-0.16------0.32-0.32---
S142NGLARLSSPVLHRLR3.2e-19--0.31--0.0321.5e-134.4e-14-6.9e-13-0.19
S255KRRLKEQSIFGDHRD-----------
S272EETHMKKSESEVEEA0.065-----0.19----9.3e-5
S274THMKKSESEVEEAAA4.1e-11--2.5e-6---0.813.6e-214.4e-18-2.1e-3-0.95
S307VASASAGSCDVPSPF-----------
S312AGSCDVPSPFNHRPG0.14----0.14-----
S320PFNHRPGSHLDSHRR-----------
S324RPGSHLDSHRRMAPT-----------
Showing 1 to 10 of 25 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS134S141S142S255S272S274S307S312S320S324T331T335S337S339S341S342T343S345T346T377S381Y597S599S601S609proteinRNASCNVmethylationCCRCCS134S141S142S255S272S274S307S312S320S324T331T335S337S339S341S342T343S345T346T377S381Y597S599S601S609proteinRNASCNVmethylationCOADS134S141S142S255S272S274S307S312S320S324T331T335S337S339S341S342T343S345T346T377S381Y597S599S601S609proteinRNASCNVmethylationGBMS134S141S142S255S272S274S307S312S320S324T331T335S337S339S341S342T343S345T346T377S381Y597S599S601S609proteinRNASCNVmethylationHNSCCS134S141S142S255S272S274S307S312S320S324T331T335S337S339S341S342T343S345T346T377S381Y597S599S601S609proteinRNASCNVmethylationLSCCS134S141S142S255S272S274S307S312S320S324T331T335S337S339S341S342T343S345T346T377S381Y597S599S601S609proteinRNASCNVmethylationLUADS134S141S142S255S272S274S307S312S320S324T331T335S337S339S341S342T343S345T346T377S381Y597S599S601S609proteinRNASCNVmethylationOVS134S141S142S255S272S274S307S312S320S324T331T335S337S339S341S342T343S345T346T377S381Y597S599S601S609proteinRNASCNVmethylationPDACS134S141S142S255S272S274S307S312S320S324T331T335S337S339S341S342T343S345T346T377S381Y597S599S601S609proteinRNASCNVmethylationUCECS134S141S142S255S272S274S307S312S320S324T331T335S337S339S341S342T343S345T346T377S381Y597S599S601S609proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.