Protein: ENSP00000309474
Gene: PSMD1

LinkedOmicsKB © 2022-2023 Zhang Lab

PSMD1:
proteasome 26S subunit, non-ATPase 1

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T273QNLRTVGTPIASVPG10126746-17169710099-102591089983778319105449518
S277TVGTPIASVPGSTNT11414-------------------
S281PIASVPGSTNTGTVP18--44----------------
S290NTGTVPGSEKDSDSM61248---4535---54----424314
S294VPGSEKDSDSMETEE9213--4410889-1265544173138174
S296GSEKDSDSMETEEKT1098273-77569981-10258999194846-56224718
S304METEEKTSSAFVGKT18--44----------------
S305ETEEKTSSAFVGKTP19----------------63--
T311SSAFVGKTPEASPEP101208105-8764373599-10259847667606314101429518
S315VGKTPEASPEPKDQT10108070-1919818099-1025994864036691668299518
Showing 1 to 10 of 12 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T273QNLRTVGTPIASVPG0.27--1.6e-17--7.8e-40.0270.27-0.053-1.1e-104.7e-3
S277TVGTPIASVPGSTNT-----------
S281PIASVPGSTNTGTVP-----------
S290NTGTVPGSEKDSDSM-0.27----------0.27
S294VPGSEKDSDSMETEE-----------
S296GSEKDSDSMETEEKT4e-22--0.93--1.9e-193.9e-226e-14--4.4e-40.28
S304METEEKTSSAFVGKT-----------
S305ETEEKTSSAFVGKTP-----------
T311SSAFVGKTPEASPEP1.4e-4--1.4e-51.6e-8--0.0794.4e-106.8e-70.5-5.5e-103.3e-8
S315VGKTPEASPEPKDQT1e-13--9.8e-11-1.9e-101.6e-17-0.76-0.24-1.5e-43.1e-4
Showing 1 to 10 of 12 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAT273S277S281S290S294S296S304S305T311S315S834S918proteinRNASCNVmethylationCCRCCT273S277S281S290S294S296S304S305T311S315S834S918proteinRNASCNVmethylationCOADT273S277S281S290S294S296S304S305T311S315S834S918proteinRNASCNVmethylationGBMT273S277S281S290S294S296S304S305T311S315S834S918proteinRNASCNVmethylationHNSCCT273S277S281S290S294S296S304S305T311S315S834S918proteinRNASCNVmethylationLSCCT273S277S281S290S294S296S304S305T311S315S834S918proteinRNASCNVmethylationLUADT273S277S281S290S294S296S304S305T311S315S834S918proteinRNASCNVmethylationOVT273S277S281S290S294S296S304S305T311S315S834S918proteinRNASCNVmethylationPDACT273S277S281S290S294S296S304S305T311S315S834S918proteinRNASCNVmethylationUCECT273S277S281S290S294S296S304S305T311S315S834S918proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.