DPYSL2: dihydropyrimidinase like 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2gse chain A
2gse chain B
2gse chain C
2gse chain D
2vm8 chain A
2vm8 chain B
2vm8 chain C
2vm8 chain D
5lxx chain A
5lxx chain B
5mkv chain A
5mkv chain B
5mkv chain C
5mkv chain D
5mle chain A
5mle chain C
5x1a chain A
5x1c chain A
5x1c chain B
5x1d chain A
5yz5 chain A
5yza chain A
5yzb chain A
6jv9 chain A
6jv9 chain B
6jv9 chain C
6jv9 chain D
6jvb chain A
6jvb chain B
6jvb chain C
6jvb chain D
7x68 chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T57 IVPGGVKT IEAHSRM 1 63 - - - - - - 63 - - - - - - - - - - - - - S62 VKTIEAHS RMVIPGG 1 72 - - - - - - 72 - - - - - - - - - - - - - S85 MPDQGMTS ADDFFQG 1 9 - - - - - - 9 - - - - - - - - - - - - - T241 EAVNRAIT IANQTNC 1 9 - - - - - - 9 - - - - - - - - - - - - - T253 TNCPLYIT KVMSKSS 1 9 - - - - - - 9 - - - - - - - - - - - - - T272 AQARKKGT VVYGEPI 1 18 - - - - - - 18 - - - - - - - - - - - - - T280 VVYGEPIT ASLGTDG 1 9 - - - - - - 9 - - - - - - - - - - - - - S282 YGEPITAS LGTDGSH 1 27 - - - - - - 27 - - - - - - - - - - - - - T285 PITASLGT DGSHYWS 1 8 - - - - - - - - - - - - 4 4 - - - - - - S288 ASLGTDGS HYWSKNW 1 10 - - - - - - - - - - 5 5 - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T57 IVPGGVKT IEAHSRM - - - - - - - - - - - S62 VKTIEAHS RMVIPGG - - - - - - - - - - - S85 MPDQGMTS ADDFFQG - - - - - - - - - - - T241 EAVNRAIT IANQTNC - - - - - - - - - - - T253 TNCPLYIT KVMSKSS - - - - - - - - - - - T272 AQARKKGT VVYGEPI - - - - - - - - - - - T280 VVYGEPIT ASLGTDG - - - - - - - - - - - S282 YGEPITAS LGTDGSH - - - - - - - - - - - T285 PITASLGT DGSHYWS - - - - - - - - - - - S288 ASLGTDGS HYWSKNW - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T57
S62
S85
T241
T253
T272
T280
S282
T285
S288
S292
S308
T313
S428
Y431
T462
S465
Y499
S507
T509
T512
T514
S517
S518
T521
S522
S537
S540
S542
S570
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T57 S62 S85 T241 T253 T272 T280 S282 T285 S288 S292 S308 T313 S428 Y431 T462 S465 Y499 S507 T509 T512 T514 S517 S518 T521 S522 S537 S540 S542 S570 protein RNA SCNV methylation CCRCC T57 S62 S85 T241 T253 T272 T280 S282 T285 S288 S292 S308 T313 S428 Y431 T462 S465 Y499 S507 T509 T512 T514 S517 S518 T521 S522 S537 S540 S542 S570 protein RNA SCNV methylation COAD T57 S62 S85 T241 T253 T272 T280 S282 T285 S288 S292 S308 T313 S428 Y431 T462 S465 Y499 S507 T509 T512 T514 S517 S518 T521 S522 S537 S540 S542 S570 protein RNA SCNV methylation GBM T57 S62 S85 T241 T253 T272 T280 S282 T285 S288 S292 S308 T313 S428 Y431 T462 S465 Y499 S507 T509 T512 T514 S517 S518 T521 S522 S537 S540 S542 S570 protein RNA SCNV methylation HNSCC T57 S62 S85 T241 T253 T272 T280 S282 T285 S288 S292 S308 T313 S428 Y431 T462 S465 Y499 S507 T509 T512 T514 S517 S518 T521 S522 S537 S540 S542 S570 protein RNA SCNV methylation LSCC T57 S62 S85 T241 T253 T272 T280 S282 T285 S288 S292 S308 T313 S428 Y431 T462 S465 Y499 S507 T509 T512 T514 S517 S518 T521 S522 S537 S540 S542 S570 protein RNA SCNV methylation LUAD T57 S62 S85 T241 T253 T272 T280 S282 T285 S288 S292 S308 T313 S428 Y431 T462 S465 Y499 S507 T509 T512 T514 S517 S518 T521 S522 S537 S540 S542 S570 protein RNA SCNV methylation OV T57 S62 S85 T241 T253 T272 T280 S282 T285 S288 S292 S308 T313 S428 Y431 T462 S465 Y499 S507 T509 T512 T514 S517 S518 T521 S522 S537 S540 S542 S570 protein RNA SCNV methylation PDAC T57 S62 S85 T241 T253 T272 T280 S282 T285 S288 S292 S308 T313 S428 Y431 T462 S465 Y499 S507 T509 T512 T514 S517 S518 T521 S522 S537 S540 S542 S570 protein RNA SCNV methylation UCEC T57 S62 S85 T241 T253 T272 T280 S282 T285 S288 S292 S308 T313 S428 Y431 T462 S465 Y499 S507 T509 T512 T514 S517 S518 T521 S522 S537 S540 S542 S570 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T57
S62
S85
T241
T253
T272
T280
S282
T285
S288
S292
S308
T313
S428
Y431
T462
S465
Y499
S507
T509
T512
T514
S517
S518
T521
S522
S537
S540
S542
S570
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
T57
S62
S85
T241
T253
T272
T280
S282
T285
S288
S292
S308
T313
S428
Y431
T462
S465
Y499
S507
T509
T512
T514
S517
S518
T521
S522
S537
S540
S542
S570
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.