HCFC1: host cell factor C1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
4go6 chain A
4go6 chain B
4go6 chain C
4go6 chain D
4n39 chain B
4n3a chain B
4n3b chain B
4n3c chain B
5lwv chain A
6ma1 chain B
6ma2 chain B
6ma3 chain B
6ma4 chain B
6ma5 chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T377 VQLVRANT NSLEVSW 3 25 - - - - - - - - 5 2 5 4 5 4 - - - - - - S379 LVRANTNS LEVSWGA 1 9 - - - - - - - - 6 3 - - - - - - - - - - S383 NTNSLEVS WGAVATA 1 9 - - - - - - - - - - - - 5 4 - - - - - - S411 ATAATATS PTPNPVP 8 395 - - - - 49 41 35 - 44 26 4 4 4 5 33 8 54 22 59 7 T413 AATATSPT PNPVPSV 10 602 13 - 26 24 54 54 90 - 52 31 5 5 31 28 14 2 46 21 88 18 S419 PTPNPVPS VPANPPK 4 104 44 - 16 16 - - - - - - 10 9 4 5 - - - - - - T502 TTGTPLVT MRPASQA 1 9 9 - - - - - - - - - - - - - - - - - - - S507 LVTMRPAS QAGKAPV 2 36 - - - - - - - - - - 4 4 - - - - - - 24 4 T535 PTQSAQGT VIGSSPQ 1 5 - - - - - - - - - - - - - - - - 4 1 - - S598 ATVKVASS PVMVSNP 10 1288 87 - 40 39 68 58 99 - 84 51 103 94 110 101 83 19 98 41 95 18
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T377 VQLVRANT NSLEVSW - - - - - - - - - - - S379 LVRANTNS LEVSWGA - - - - - - - - - - - S383 NTNSLEVS WGAVATA - - - - - - - - - - - S411 ATAATATS PTPNPVP -0.05 - - 0.012 - -0.67 - - - -4.5e-8 - T413 AATATSPT PNPVPSV -0.2 - -0.036 1.5e-3 - 0.81 - -0.35 - -1.4e-5 0.42 S419 PTPNPVPS VPANPPK - - - - - - - - - - - T502 TTGTPLVT MRPASQA - - - - - - - - - - - S507 LVTMRPAS QAGKAPV - - - - - - - - - - - T535 PTQSAQGT VIGSSPQ - - - - - - - - - - - S598 ATVKVASS PVMVSNP -0.014 - 0.46 -4.2e-5 - 0.025 -0.19 -6.7e-12 -0.014 1.9e-6 0.97
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T377
S379
S383
S411
T413
S419
T502
S507
T535
S598
T627
S628
T629
S666
S669
S789
S794
S1205
S1224
S1246
S1398
T1400
T1491
S1497
S1507
S1838
T1844
S1941
T1942
S2019
S2020
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T377 S379 S383 S411 T413 S419 T502 S507 T535 S598 T627 S628 T629 S666 S669 S789 S794 S1205 S1224 S1246 S1398 T1400 T1491 S1497 S1507 S1838 T1844 S1941 T1942 S2019 S2020 protein RNA SCNV methylation CCRCC T377 S379 S383 S411 T413 S419 T502 S507 T535 S598 T627 S628 T629 S666 S669 S789 S794 S1205 S1224 S1246 S1398 T1400 T1491 S1497 S1507 S1838 T1844 S1941 T1942 S2019 S2020 protein RNA SCNV methylation COAD T377 S379 S383 S411 T413 S419 T502 S507 T535 S598 T627 S628 T629 S666 S669 S789 S794 S1205 S1224 S1246 S1398 T1400 T1491 S1497 S1507 S1838 T1844 S1941 T1942 S2019 S2020 protein RNA SCNV methylation GBM T377 S379 S383 S411 T413 S419 T502 S507 T535 S598 T627 S628 T629 S666 S669 S789 S794 S1205 S1224 S1246 S1398 T1400 T1491 S1497 S1507 S1838 T1844 S1941 T1942 S2019 S2020 protein RNA SCNV methylation HNSCC T377 S379 S383 S411 T413 S419 T502 S507 T535 S598 T627 S628 T629 S666 S669 S789 S794 S1205 S1224 S1246 S1398 T1400 T1491 S1497 S1507 S1838 T1844 S1941 T1942 S2019 S2020 protein RNA SCNV methylation LSCC T377 S379 S383 S411 T413 S419 T502 S507 T535 S598 T627 S628 T629 S666 S669 S789 S794 S1205 S1224 S1246 S1398 T1400 T1491 S1497 S1507 S1838 T1844 S1941 T1942 S2019 S2020 protein RNA SCNV methylation LUAD T377 S379 S383 S411 T413 S419 T502 S507 T535 S598 T627 S628 T629 S666 S669 S789 S794 S1205 S1224 S1246 S1398 T1400 T1491 S1497 S1507 S1838 T1844 S1941 T1942 S2019 S2020 protein RNA SCNV methylation OV T377 S379 S383 S411 T413 S419 T502 S507 T535 S598 T627 S628 T629 S666 S669 S789 S794 S1205 S1224 S1246 S1398 T1400 T1491 S1497 S1507 S1838 T1844 S1941 T1942 S2019 S2020 protein RNA SCNV methylation PDAC T377 S379 S383 S411 T413 S419 T502 S507 T535 S598 T627 S628 T629 S666 S669 S789 S794 S1205 S1224 S1246 S1398 T1400 T1491 S1497 S1507 S1838 T1844 S1941 T1942 S2019 S2020 protein RNA SCNV methylation UCEC T377 S379 S383 S411 T413 S419 T502 S507 T535 S598 T627 S628 T629 S666 S669 S789 S794 S1205 S1224 S1246 S1398 T1400 T1491 S1497 S1507 S1838 T1844 S1941 T1942 S2019 S2020 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T377
S379
S383
S411
T413
S419
T502
S507
T535
S598
T627
S628
T629
S666
S669
S789
S794
S1205
S1224
S1246
S1398
T1400
T1491
S1497
S1507
S1838
T1844
S1941
T1942
S2019
S2020
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
T377
S379
S383
S411
T413
S419
T502
S507
T535
S598
T627
S628
T629
S666
S669
S789
S794
S1205
S1224
S1246
S1398
T1400
T1491
S1497
S1507
S1838
T1844
S1941
T1942
S2019
S2020
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.