RACGAP1: Rac GTPase activating protein 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2ovj chain A
3w6r chain A
3wpq chain A
3wpq chain B
3wps chain A
3wps chain B
4b6d chain A
4b6d chain B
4b6d chain C
4b6d chain D
4b6d chain E
4b6d chain F
5c2j chain A
5c2k chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S114 LMCDTSGS IQLSEEQ 2 18 8 - - - - - - - - - 5 5 - - - - - - - - S123 QLSEEQKS ALAFLNR 2 17 - - - - - - - - - - - - - - 7 1 - - - 9 S135 LNRGQPSS SNAGNKR 1 9 - - - - - - - - - - 5 4 - - - - - - - - S136 NRGQPSSS NAGNKRL 1 9 - - - - - - - - - - - - - - - - - - - 9 S144 NAGNKRLS TIDESGS 3 48 - - - - - - 9 - 18 11 5 5 - - - - - - - - T145 AGNKRLST IDESGSI 1 8 - - - - - - - - 5 3 - - - - - - - - - - S154 DESGSILS DISFDKT 2 18 - - - - - - 9 - - - - - - - - - - - - 9 S157 GSILSDIS FDKTDES 3 141 - - - - - - 18 - 73 44 - - - - - - - - 6 - S164 SFDKTDES LDWDSSL 3 94 - - - - - - - - 5 4 20 20 - - - - - - 29 16 S169 DESLDWDS SLVKTFK 1 17 - - - - - - - - - - - - - - - - - - 13 4
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S114 LMCDTSGS IQLSEEQ - - - - - - - - - - - S123 QLSEEQKS ALAFLNR - - - - - - - - - - - S135 LNRGQPSS SNAGNKR - - - - - - - - - - - S136 NRGQPSSS NAGNKRL - - - - - - - - - - - S144 NAGNKRLS TIDESGS - - - - - - - - - - - T145 AGNKRLST IDESGSI - - - - - - - - - - - S154 DESGSILS DISFDKT - - - - - - - - - - - S157 GSILSDIS FDKTDES 2.6e-5 - - - - 2.6e-5 - - - - - S164 SFDKTDES LDWDSSL 8.7e-7 - - - - - 2.1e-7 - - - 0.077 S169 DESLDWDS SLVKTFK - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S114
S123
S135
S136
S144
T145
S154
S157
S164
S169
S170
S203
S206
S214
T249
S257
S274
T277
T342
S486
T579
T580
T588
S590
S615
S628
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S114 S123 S135 S144 T145 S154 S157 S164 S169 S170 S203 S206 S214 T249 S257 S274 T277 T342 S486 T579 T580 T588 S590 S615 S628 protein RNA SCNV methylation CCRCC S114 S123 S135 S144 T145 S154 S157 S164 S169 S170 S203 S206 S214 T249 S257 S274 T277 T342 S486 T579 T580 T588 S590 S615 S628 protein RNA SCNV methylation COAD S114 S123 S135 S144 T145 S154 S157 S164 S169 S170 S203 S206 S214 T249 S257 S274 T277 T342 S486 T579 T580 T588 S590 S615 S628 protein RNA SCNV methylation GBM S114 S123 S135 S144 T145 S154 S157 S164 S169 S170 S203 S206 S214 T249 S257 S274 T277 T342 S486 T579 T580 T588 S590 S615 S628 protein RNA SCNV methylation HNSCC S114 S123 S135 S144 T145 S154 S157 S164 S169 S170 S203 S206 S214 T249 S257 S274 T277 T342 S486 T579 T580 T588 S590 S615 S628 protein RNA SCNV methylation LSCC S114 S123 S135 S144 T145 S154 S157 S164 S169 S170 S203 S206 S214 T249 S257 S274 T277 T342 S486 T579 T580 T588 S590 S615 S628 protein RNA SCNV methylation LUAD S114 S123 S135 S144 T145 S154 S157 S164 S169 S170 S203 S206 S214 T249 S257 S274 T277 T342 S486 T579 T580 T588 S590 S615 S628 protein RNA SCNV methylation OV S114 S123 S135 S144 T145 S154 S157 S164 S169 S170 S203 S206 S214 T249 S257 S274 T277 T342 S486 T579 T580 T588 S590 S615 S628 protein RNA SCNV methylation PDAC S114 S123 S135 S144 T145 S154 S157 S164 S169 S170 S203 S206 S214 T249 S257 S274 T277 T342 S486 T579 T580 T588 S590 S615 S628 protein RNA SCNV methylation UCEC S114 S123 S135 S144 T145 S154 S157 S164 S169 S170 S203 S206 S214 T249 S257 S274 T277 T342 S486 T579 T580 T588 S590 S615 S628 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S114
S123
S135
S136
S144
T145
S154
S157
S164
S169
S170
S203
S206
S214
T249
S257
S274
T277
T342
S486
T579
T580
T588
S590
S615
S628
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S114
S123
S135
S136
S144
T145
S154
S157
S164
S169
S170
S203
S206
S214
T249
S257
S274
T277
T342
S486
T579
T580
T588
S590
S615
S628
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.