Protein: ENSP00000310129
Gene: PSMD2

LinkedOmicsKB © 2022-2023 Zhang Lab

PSMD2:
proteasome 26S subunit, non-ATPase 2

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S16APVQPQQSPAAAPGG101545122-103809710099-10862108991101017618105449518
T24PAAAPGGTDEKPSGK19------------------72
S46KDKEQELSEEDKQLQ868054-7956--35-684083754944--6022132
S69RLGEKDTSLYRPALE19------9-------------
S85LRRQIRSSTTSMTSV324--------64--54--41--
S134SVLAMTMSGERECLK117------17-------------
S147LKYRLVGSQEELASW1066356-8-7290-10862107922723339521913
S361ENNRFGGSGSQVDSA862355---788390-1272322--831934128718
S363NRFGGSGSQVDSARM1080490-4543293353-493110395444149112611465
S367GSGSQVDSARMNLAS237------9-1810----------
Showing 1 to 10 of 12 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S16APVQPQQSPAAAPGG4.1e-61-4.1e-176.4e-31-1e-199.8e-340.157.4e-5-0.920.85
T24PAAAPGGTDEKPSGK-----------
S46KDKEQELSEEDKQLQ0.016-0.045--2.4e-71.6e-3-0.65--8.1e-6-
S69RLGEKDTSLYRPALE-----------
S85LRRQIRSSTTSMTSV-----------
S134SVLAMTMSGERECLK-----------
S147LKYRLVGSQEELASW2.4e-10----0.0256.7e-160.51---
S361ENNRFGGSGSQVDSA-0.01--0.96---8.2e-6--8.5e-42.3e-5-0.025
S363NRFGGSGSQVDSARM-7.1e-4--2.8e-51.2e-3-0.67-2.5e-13-0.002-0.0083.6e-6-
S367GSGSQVDSARMNLAS-----------
Showing 1 to 10 of 12 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS16T24S46S69S85S134S147S361S363S367S435S436proteinRNASCNVmethylationCCRCCS16T24S46S69S85S134S147S361S363S367S435S436proteinRNASCNVmethylationCOADS16T24S46S69S85S134S147S361S363S367S435S436proteinRNASCNVmethylationGBMS16T24S46S69S85S134S147S361S363S367S435S436proteinRNASCNVmethylationHNSCCS16T24S46S69S85S134S147S361S363S367S435S436proteinRNASCNVmethylationLSCCS16T24S46S69S85S134S147S361S363S367S435S436proteinRNASCNVmethylationLUADS16T24S46S69S85S134S147S361S363S367S435S436proteinRNASCNVmethylationOVS16T24S46S69S85S134S147S361S363S367S435S436proteinRNASCNVmethylationPDACS16T24S46S69S85S134S147S361S363S367S435S436proteinRNASCNVmethylationUCECS16T24S46S69S85S134S147S361S363S367S435S436proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.