GRB7: growth factor receptor bound protein 7
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1mw4 chain A
1wgr chain A
2l4k chain A
2qms chain A
2qms chain B
2qms chain C
2qms chain D
3pqz chain A
3pqz chain B
3pqz chain C
3pqz chain D
4wwq chain A
4wwq chain B
4x6s chain A
4x6s chain B
5d0j chain A
5d0j chain B
5d0j chain C
5d0j chain D
5eel chain A
5eel chain B
5eel chain C
5eel chain D
5eel chain E
5eel chain F
5eeq chain A
5eeq chain B
5tyi chain A
5tyi chain B
5tyi chain C
5tyi chain D
5u06 chain A
5u06 chain B
5u06 chain C
5u06 chain D
5u1q chain A
5u1q chain B
5u1q chain C
5u1q chain D
7mp3 chain A
7mp3 chain B
7mp3 chain C
7mp3 chain D
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
Loading, please wait
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S6 __MELDLS PPHLSSS 1 8 - - - - - - - - - - - - - - - - - - 5 3 S11 DLSPPHLS SSPEDLC 1 8 - - - - - - - - - - - - - - - - - - 5 3 S12 LSPPHLSS SPEDLCP 1 8 - - - - - - - - - - - - - - - - - - 5 3 S13 SPPHLSSS PEDLCPA 1 7 - - - - - - - - - - - - - - - - - - 5 2 T23 DLCPAPGT PPGTPRP 1 15 - - - - - - - - - - - - - - - - - - 10 5 S42 LPEEVKRS QPLLIPT 6 133 51 - 4 4 - - - - - - 5 5 5 4 16 2 - - 24 13 T62 REEERRAT SLPSIPN 2 46 - - - - 9 9 - - - - - - - - - - - - 21 7 S63 EEERRATS LPSIPNP 9 1196 104 - 75 62 87 90 - - 84 48 92 86 88 78 51 8 97 40 88 18 S66 RRATSLPS IPNPFPE 9 288 47 - 28 28 5 4 - - 27 18 19 16 35 33 11 2 3 2 10 - S76 NPFPELCS PPSQSPI 9 595 59 - 40 29 5 4 - - 108 61 75 68 48 45 13 4 4 2 23 7
Tumor and normal comparison
Loading, please wait
Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S6 __MELDLS PPHLSSS - - - - - - - - - - - S11 DLSPPHLS SSPEDLC - - - - - - - - - - - S12 LSPPHLSS SPEDLCP - - - - - - - - - - - S13 SPPHLSSS PEDLCPA - - - - - - - - - - - T23 DLCPAPGT PPGTPRP - - - - - - - - - - - S42 LPEEVKRS QPLLIPT 0.067 - - - - - - - - - 0.067 T62 REEERRAT SLPSIPN - - - - - - - - - - - S63 EEERRATS LPSIPNP -0.78 - -1.2e-3 0.73 - -0.44 0.73 -0.34 - 8.8e-3 0.36 S66 RRATSLPS IPNPFPE -2.7e-3 - -0.081 - - -0.57 - -0.004 - - - S76 NPFPELCS PPSQSPI -4.6e-23 - 0.76 - - -9e-18 -4.1e-11 -9.3e-7 - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
Loading, please wait
all sites
S6
S11
S12
S13
T23
S42
T62
S63
S66
S76
S79
S81
S99
Y107
S194
S256
S361
S366
S368
T371
S393
S411
S417
S460
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S6 S11 S12 S13 T23 S42 T62 S63 S66 S76 S79 S81 S99 Y107 S194 S256 S361 S366 S368 T371 S393 S411 S417 S460 protein RNA SCNV methylation CCRCC S6 S11 S12 S13 T23 S42 T62 S63 S66 S76 S79 S81 S99 Y107 S194 S256 S361 S366 S368 T371 S393 S411 S417 S460 protein RNA SCNV methylation COAD S6 S11 S12 S13 T23 S42 T62 S63 S66 S76 S79 S81 S99 Y107 S194 S256 S361 S366 S368 T371 S393 S411 S417 S460 protein RNA SCNV methylation GBM S6 S11 S12 S13 T23 S42 T62 S63 S66 S76 S79 S81 S99 Y107 S194 S256 S361 S366 S368 T371 S393 S411 S417 S460 protein RNA SCNV methylation HNSCC S6 S11 S12 S13 T23 S42 T62 S63 S66 S76 S79 S81 S99 Y107 S194 S256 S361 S366 S368 T371 S393 S411 S417 S460 protein RNA SCNV methylation LSCC S6 S11 S12 S13 T23 S42 T62 S63 S66 S76 S79 S81 S99 Y107 S194 S256 S361 S366 S368 T371 S393 S411 S417 S460 protein RNA SCNV methylation LUAD S6 S11 S12 S13 T23 S42 T62 S63 S66 S76 S79 S81 S99 Y107 S194 S256 S361 S366 S368 T371 S393 S411 S417 S460 protein RNA SCNV methylation OV S6 S11 S12 S13 T23 S42 T62 S63 S66 S76 S79 S81 S99 Y107 S194 S256 S361 S366 S368 T371 S393 S411 S417 S460 protein RNA SCNV methylation PDAC S6 S11 S12 S13 T23 S42 T62 S63 S66 S76 S79 S81 S99 Y107 S194 S256 S361 S366 S368 T371 S393 S411 S417 S460 protein RNA SCNV methylation UCEC S6 S11 S12 S13 T23 S42 T62 S63 S66 S76 S79 S81 S99 Y107 S194 S256 S361 S366 S368 T371 S393 S411 S417 S460 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S6
S11
S12
S13
T23
S42
T62
S63
S66
S76
S79
S81
S99
Y107
S194
S256
S361
S366
S368
T371
S393
S411
S417
S460
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S6
S11
S12
S13
T23
S42
T62
S63
S66
S76
S79
S81
S99
Y107
S194
S256
S361
S366
S368
T371
S393
S411
S417
S460
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.