Protein: ENSP00000311713
Gene: OXSR1

LinkedOmicsKB © 2022-2023 Zhang Lab

OXSR1:
oxidative stress responsive kinase 1

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S246TLQNDPPSLETGVQD235----------541313------
S269KSFRKMISLCLQKDP336--88--10---55--------
T310KTLQRAPTISERAKK842230---827917---302912133763916302
S324KVRRVPGSSGRLHKT1080264-7659666036-161083776360471228141813
S325VRRVPGSSGRLHKTE1093142-7958535490-925243421412561210544767
S339EDGGWEWSDDEFDEE101517113-103809710099-1086210394102928319105449518
S347DDEFDEESEEGKAAI46316-------5454------245
S359AAISQLRSPRVKESI101490122-9068928799-10862108991101017618105448318
S422AKTAQALSSGSGSQE4449-----18---55------52
S423KTAQALSSGSGSQET731723-2323--9-6350474439----3614
Showing 1 to 10 of 14 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S246TLQNDPPSLETGVQD-----------
S269KSFRKMISLCLQKDP-----------
T310KTLQRAPTISERAKK-3.2e-9---4.5e-9---0.002---0.19-
S324KVRRVPGSSGRLHKT-0.078--2.3e-72.9e-3--0.25-0.0160.088-9.6e-3-
S325VRRVPGSSGRLHKTE-8.4e-6--0.21-0.49--1.6e-80.21-0.21-6.5e-9-
S339EDGGWEWSDDEFDEE-7.6e-37--2.6e-16-1.2e-3-0.82-6.6e-16-7.9e-12-0.061-5.6e-4-9.8e-6
S347DDEFDEESEEGKAAI-----------
S359AAISQLRSPRVKESI-8.1e-6-1.6e-10-8.2e-5--6.4e-130.045-9.9e-100.81-6.3e-100.031
S422AKTAQALSSGSGSQE-----------
S423KTAQALSSGSGSQET-2.2e-4-0.49----1.6e-3-1.5e-11--0.068
Showing 1 to 10 of 14 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS246S269T310S324S325S339S347S359S422S423S425S427S510S525proteinRNASCNVmethylationCCRCCS246S269T310S324S325S339S347S359S422S423S425S427S510S525proteinRNASCNVmethylationCOADS246S269T310S324S325S339S347S359S422S423S425S427S510S525proteinRNASCNVmethylationGBMS246S269T310S324S325S339S347S359S422S423S425S427S510S525proteinRNASCNVmethylationHNSCCS246S269T310S324S325S339S347S359S422S423S425S427S510S525proteinRNASCNVmethylationLSCCS246S269T310S324S325S339S347S359S422S423S425S427S510S525proteinRNASCNVmethylationLUADS246S269T310S324S325S339S347S359S422S423S425S427S510S525proteinRNASCNVmethylationOVS246S269T310S324S325S339S347S359S422S423S425S427S510S525proteinRNASCNVmethylationPDACS246S269T310S324S325S339S347S359S422S423S425S427S510S525proteinRNASCNVmethylationUCECS246S269T310S324S325S339S347S359S422S423S425S427S510S525proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.